Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN2841348 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12) (AA 828-859), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 828-859, C-Term
- Antibody clone number
- RB0976
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references MicroRNA-130a Targets MAP3K12 to Modulate Diabetic Endothelial Progenitor Cell Function.
The DLK gene is a transcriptional target of PPARĪ³.
SP3 acts as a positive regulator on the core promoter of human ZPK gene.
MAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/dual leucine zipper-bearing kinase/leucine zipper protein kinase.
ZPK inhibits PKA induced transcriptional activation by CREB and blocks retinoic acid induced neuronal differentiation.
Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin.
Activation of the JNK pathway by distantly related protein kinases, MEKK and MUK.
Ye M, Li D, Yang J, Xie J, Yu F, Ma Y, Zhu X, Zhao J, Lv Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;36(2):712-26
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;36(2):712-26
The DLK gene is a transcriptional target of PPARĪ³.
Couture JP, Blouin R
The Biochemical journal 2011 Aug 15;438(1):93-101
The Biochemical journal 2011 Aug 15;438(1):93-101
SP3 acts as a positive regulator on the core promoter of human ZPK gene.
Itoh A, Wang Z, Ito Y, Reddy UR, Itoh T
Biochemical and biophysical research communications 2004 Jan 16;313(3):612-8
Biochemical and biophysical research communications 2004 Jan 16;313(3):612-8
MAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/dual leucine zipper-bearing kinase/leucine zipper protein kinase.
Fukuyama K, Yoshida M, Yamashita A, Deyama T, Baba M, Suzuki A, Mohri H, Ikezawa Z, Nakajima H, Hirai S, Ohno S
The Journal of biological chemistry 2000 Jul 14;275(28):21247-54
The Journal of biological chemistry 2000 Jul 14;275(28):21247-54
ZPK inhibits PKA induced transcriptional activation by CREB and blocks retinoic acid induced neuronal differentiation.
Reddy UR, Basu A, Bannerman P, Ikegaki N, Reddy CD, Pleasure D
Oncogene 1999 Aug 5;18(31):4474-84
Oncogene 1999 Aug 5;18(31):4474-84
Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin.
Mata M, Merritt SE, Fan G, Yu GG, Holzman LB
The Journal of biological chemistry 1996 Jul 12;271(28):16888-96
The Journal of biological chemistry 1996 Jul 12;271(28):16888-96
Activation of the JNK pathway by distantly related protein kinases, MEKK and MUK.
Hirai S, Izawa M, Osada S, Spyrou G, Ohno S
Oncogene 1996 Feb 1;12(3):641-50
Oncogene 1996 Feb 1;12(3):641-50
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
