Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN359408 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12) (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- C-Term
- Vial size
- 0.4 mL
- Storage
- Store the antibody at 2 - 8°C up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references SP3 acts as a positive regulator on the core promoter of human ZPK gene.
MAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/dual leucine zipper-bearing kinase/leucine zipper protein kinase.
ZPK inhibits PKA induced transcriptional activation by CREB and blocks retinoic acid induced neuronal differentiation.
Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin.
It is better to travel hopefully ellipsis
Itoh A, Wang Z, Ito Y, Reddy UR, Itoh T
Biochemical and biophysical research communications 2004 Jan 16;313(3):612-8
Biochemical and biophysical research communications 2004 Jan 16;313(3):612-8
MAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/dual leucine zipper-bearing kinase/leucine zipper protein kinase.
Fukuyama K, Yoshida M, Yamashita A, Deyama T, Baba M, Suzuki A, Mohri H, Ikezawa Z, Nakajima H, Hirai S, Ohno S
The Journal of biological chemistry 2000 Jul 14;275(28):21247-54
The Journal of biological chemistry 2000 Jul 14;275(28):21247-54
ZPK inhibits PKA induced transcriptional activation by CREB and blocks retinoic acid induced neuronal differentiation.
Reddy UR, Basu A, Bannerman P, Ikegaki N, Reddy CD, Pleasure D
Oncogene 1999 Aug 5;18(31):4474-84
Oncogene 1999 Aug 5;18(31):4474-84
Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin.
Mata M, Merritt SE, Fan G, Yu GG, Holzman LB
The Journal of biological chemistry 1996 Jul 12;271(28):16888-96
The Journal of biological chemistry 1996 Jul 12;271(28):16888-96
It is better to travel hopefully ellipsis
Curran DP
Chemistry & biology 1996 Aug 1;3(8):641-2
Chemistry & biology 1996 Aug 1;3(8):641-2
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC