BS7885

antibody from Bioworld Technology, Inc
Targeting: NEIL1 FLJ22402, FPG1, hFPG1, NEI1
Provider product page for BS7885
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS7885 - Provider product page
Provider
Bioworld Technology, Inc
Product name
NEIL1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human NEIL1.
Description
NEIL1, NEIL2 and NEIL3, also known as Endonuclease VIII-like 1,2 and 3 or DNA-(apurinic or apyrimidinic site) lyase NEIL 1, 2 and 3, are nuclear proteins involved in the repair of DNA damaged by oxidation. The NEIL proteins belong to the FPG familiy of proteins. They act as DNA glycosylases that can recognize and remove damaged bases, leaving an abasic site. NEIL3, however, lacks the proline residue at the N-terminus which acts as the active site residue found in NEIL1 and NEIL2. NEIL1 is a ubiquitiously expressed protein that is up-regulated during S-phase. NEIL2 is expressed primarily in testis, heart, skeletal muscle, placenta, brain, kidney and liver while NEIL3 is detected primarily in thymus and testis.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
NEIL1 protein structure - BS7885 shown in red.