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- Antibody Data
- Antigen structure
- References [197]
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- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 10904-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10904-1-AP, RRID:AB_2224377
- Product name
- IBA1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated IBA1 antibody (Cat. #10904-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Coeloglossum viride var. bracteatum extract attenuates Aβ-induced toxicity by inhibiting RIP1-driven inflammation and necroptosis.
Gut Microbiota Disorders Promote Inflammation and Aggravate Spinal Cord Injury Through the TLR4/MyD88 Signaling Pathway.
NU9056, a KAT 5 Inhibitor, Treatment Alleviates Brain Dysfunction by Inhibiting NLRP3 Inflammasome Activation, Affecting Gut Microbiota, and Derived Metabolites in LPS-Treated Mice.
Rufinamide (RUF) suppresses inflammation and maintains the integrity of the blood-brain barrier during kainic acid-induced brain damage.
Novel Scalable and Simplified System to Generate Microglia-Containing Cerebral Organoids From Human Induced Pluripotent Stem Cells.
Isoliquiritigenin Confers Neuroprotection and Alleviates Amyloid-β42-Induced Neuroinflammation in Microglia by Regulating the Nrf2/NF-κB Signaling.
Class IIa HDAC Downregulation Contributes to Surgery-Induced Cognitive Impairment Through HMGB1-Mediated Inflammatory Response in the Hippocampi of Aged Mice.
Traumatic Brain Injury Accelerates the Onset of Cognitive Dysfunction and Aggravates Alzheimer's-Like Pathology in the Hippocampus by Altering the Phenotype of Microglia in the APP/PS1 Mouse Model.
Catalytic patch with redox Cr/CeO2 nanozyme of noninvasive intervention for brain trauma.
Effects of prenatal photobiomodulation treatment on neonatal hypoxic ischemia in rat offspring.
Edaravone attenuates cadmium-induced toxicity by inhibiting oxidative stress and inflammation in ICR mice.
Nilotinib inhibits microglia-mediated neuroinflammation to protect against dopaminergic neuronal death in Parkinson's disease models.
Sleep disturbance induces depressive behaviors and neuroinflammation by altering the circadian oscillations of clock genes in rats.
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Bioinformatics analysis identifies CSF1R as an essential gene mediating Neuropathic pain - Experimental research.
Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway.
Neuroprotective effects of liraglutide against inflammation through the AMPK/NF-κB pathway in a mouse model of Parkinson's disease.
TC10, a Rho family GTPase, is required for efficient axon regeneration in a neuron-autonomous manner.
A diet high in sugar and fat influences neurotransmitter metabolism and then affects brain function by altering the gut microbiota.
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Protective effects of melatonin on the white matter damage of neonatal rats by regulating NLRP3 inflammasome activity.
Edaravone attenuates H2O2 or glutamate-induced toxicity in hippocampal neurons and improves AlCl3/D-galactose induced cognitive impairment in mice.
Blocking Hepatoma-Derived Growth Factor Attenuates Vasospasm and Neuron Cell Apoptosis in Rats Subjected to Subarachnoid Hemorrhage.
Increased Expression of Thymic Stromal Lymphopoietin in Chronic Constriction Injury of Rat Nerve.
Minocycline alleviates depression-like symptoms by rescuing decrease in neurogenesis in dorsal hippocampus via blocking microglia activation/phagocytosis.
Role of lipocalin-2 in extracellular peroxiredoxin 2-induced brain swelling, inflammation and neuronal death.
Adrenomedullin 2 attenuates LPS-induced inflammation in microglia cells by receptor-mediated cAMP-PKA pathway.
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Annexin A1 Attenuates Neutrophil Migration and IL-6 Expression through Fpr2 in a Mouse Model of Streptococcus suis-Induced Meningitis.
Gisenoside Rg1 attenuates cadmium-induced neurotoxicity in vitro and in vivo by attenuating oxidative stress and inflammation.
Schizandrin A ameliorates cognitive functions via modulating microglial polarisation in Alzheimer's disease mice.
Integration of Raman spectra with transcriptome data in glioblastoma multiforme defines tumour subtypes and predicts patient outcome.
Axl Alleviates Neuroinflammation and Delays Japanese Encephalitis Progression in Mice.
8-Formylophiopogonanone B antagonizes doxorubicin-induced cardiotoxicity by suppressing heme oxygenase-1-dependent myocardial inflammation and fibrosis.
Reactive microglia enhance the transmission of exosomal α-synuclein via toll-like receptor 2.
Phytogalactolipid dLGG Inhibits Mouse Melanoma Brain Metastasis through Regulating Oxylipin Activity and Re-Programming Macrophage Polarity in the Tumor Microenvironment.
Phosphatase and Tensin Homolog Deleted on Chromosome Ten Knockdown Attenuates Cognitive Deficits by Inhibiting Neuroinflammation in a Mouse Model of Perioperative Neurocognitive Disorder.
Injectable Gelatin Hydrogel Suppresses Inflammation and Enhances Functional Recovery in a Mouse Model of Intracerebral Hemorrhage.
Microglia TREM2: A Potential Role in the Mechanism of Action of Electroacupuncture in an Alzheimer's Disease Animal Model.
Nrf2 Ablation Promotes Alzheimer's Disease-Like Pathology in APP/PS1 Transgenic Mice: The Role of Neuroinflammation and Oxidative Stress.
Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia.
Resveratrol Preincubation Enhances the Therapeutic Efficacy of hUC-MSCs by Improving Cell Migration and Modulating Neuroinflammation Mediated by MAPK Signaling in a Mouse Model of Alzheimer's Disease.
Kalirin-7 contributes to type 2 diabetic neuropathic pain via the postsynaptic density-95/N-methyl-D-aspartate receptor 2B-dependent N-methyl-D-aspartate receptor 2B phosphorylation in the spinal cord in rats.
Caveolin-1 in spinal cord modulates type-2 diabetic neuropathic pain through the Rac1/NOX2/NR2B signaling pathway.
FTY720 Prevents Spatial Memory Impairment in a Rat Model of Chronic Cerebral Hypoperfusion via a SIRT3-Independent Pathway.
LongShengZhi Capsule Attenuates Alzheimer-Like Pathology in APP/PS1 Double Transgenic Mice by Reducing Neuronal Oxidative Stress and Inflammation.
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
Glucagon-like peptide-1 receptor agonist Exendin-4 improves neurological outcomes by attenuating TBI- induced inflammatory responses and MAPK activation in rats.
MSC-derived exosomes promote recovery from traumatic brain injury via microglia/macrophages in rat.
MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis.
Metamizole relieves pain by influencing cytokine levels in dorsal root ganglia in a rat model of neuropathic pain.
Neuroprotective mechanism of L-cysteine after subarachnoid hemorrhage.
IL-1β/IL-1R1 signaling induced by intranasal lipopolysaccharide infusion regulates alpha-Synuclein pathology in the olfactory bulb, substantia nigra and striatum.
Morphological analyzes of microglia heterogeneity and dynamics during photoreceptor degeneration in vitro: Presumptive dark microglia in porcine retina.
Attenuation of Acute Intracerebral Hemorrhage-Induced Microglial Activation and Neuronal Death Mediated by the Blockade of Metabotropic Glutamate Receptor 5 In Vivo.
Changes in macrophage inflammatory protein-1 (MIP-1) family members expression induced by traumatic brain injury in mice.
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype.
Carbon dot targeting to nitrogen signaling molecules for inhibiting neuronal death.
Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity.
The effect of swimming exercise and diet on the hypothalamic inflammation of ApoE-/- mice based on SIRT1-NF-κB-GnRH expression.
Natural Xanthone α-Mangostin Inhibits LPS-Induced Microglial Inflammatory Responses and Memory Impairment by Blocking the TAK1/NF-κB Signaling Pathway.
Over-Expression of Allograft Inflammatory Factor-1 (AIF-1) in Patients with Rheumatoid Arthritis.
Chemokine CCL2 contributes to BBB disruption via the p38 MAPK signaling pathway following acute intracerebral hemorrhage.
BHBA treatment improves cognitive function by targeting pleiotropic mechanisms in transgenic mouse model of Alzheimer's disease.
Synaptic alterations and immune response are sexually dimorphic in a non-pertussis toxin model of experimental autoimmune encephalomyelitis.
Scorpion alleviates bone cancer pain through inhibition of bone destruction and glia activation.
Protective role of cinnabar and realgar in Hua-Feng-Dan against LPS plus rotenone-induced neurotoxicity and disturbance of gut microbiota in rats.
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Photobiomodulation therapy for repeated closed head injury in rats.
Acetate attenuates perioperative neurocognitive disorders in aged mice.
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Menthol protects dopaminergic neurons against inflammation-mediated damage in lipopolysaccharide (LPS)-Evoked model of Parkinson's disease.
Glutathione Depletion and Parkinsonian Neurotoxin MPP+-Induced TRPM2 Channel Activation Play Central Roles in Oxidative Cytotoxicity and Inflammation in Microglia.
Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition.
CCR4 antagonist (C021) influences the level of nociceptive factors and enhances the analgesic potency of morphine in a rat model of neuropathic pain.
Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages.
Cu(II) disrupts autophagy-mediated lysosomal degradation of oligomeric Aβ in microglia via mTOR-TFEB pathway.
Mefenamic acid can attenuate depressive symptoms by suppressing microglia activation induced upon chronic stress.
Sirtuin 2 Inhibition Attenuates Sevoflurane-Induced Learning and Memory Deficits in Developing Rats via Modulating Microglial Activation.
The blockade of CC chemokine receptor type 1 influences the level of nociceptive factors and enhances opioid analgesic potency in a rat model of neuropathic pain.
Intracerebral Hemorrhage-Induced Brain Injury in Rats: the Role of Extracellular Peroxiredoxin 2.
Interferon-λ Attenuates Rabies Virus Infection by Inducing Interferon-Stimulated Genes and Alleviating Neurological Inflammation.
H2S attenuates injury after ischemic stroke by diminishing the assembly of CaMKII with ASK1-MKK3-p38 signaling module.
Exosomes Derived From Bone Marrow Mesenchymal Stem Cells Inhibit Complement Activation In Rats With Spinal Cord Injury.
Expression of cysteinyl leukotriene receptor in brain tissues of rats with Streptococcus pneumoniae meningitis.
Naringenin Produces Neuroprotection Against LPS-Induced Dopamine Neurotoxicity via the Inhibition of Microglial NLRP3 Inflammasome Activation.
Pharmacological Blockade of Spinal CXCL3/CXCR2 Signaling by NVP CXCR2 20, a Selective CXCR2 Antagonist, Reduces Neuropathic Pain Following Peripheral Nerve Injury.
Ghrelin Attenuates Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis Involving NLRP3 Inflammasome Signaling Pathway and Pyroptosis.
Melatonin alleviates cognition impairment by antagonizing brain insulin resistance in aged rats fed a high-fat diet.
Intracerebroventricular administration of lupus serum induces microglia activation and leukocyte adhesion in the cerebromicrovasculature of mice.
Antinociceptive effect of isoorientin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Farrerol protects dopaminergic neurons in a rat model of lipopolysaccharide-induced Parkinson's disease by suppressing the activation of the AKT and NF-κB signaling pathways.
Nanozyme-Based Bandage with Single-Atom Catalysis for Brain Trauma.
TREM2 deficiency aggravates α-synuclein-induced neurodegeneration and neuroinflammation in Parkinson's disease models.
Splicing repression is a major function of TDP-43 in motor neurons.
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression.
Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1.
Complement Inhibition Attenuates Early Erythrolysis in the Hematoma and Brain Injury in Aged Rats.
Naringenin targets on astroglial Nrf2 to support dopaminergic neurons.
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Redox Trimetallic Nanozyme with Neutral Environment Preference for Brain Injury.
Microglia as modulators of exosomal alpha-synuclein transmission.
Melatonin receptor activation provides cerebral protection after traumatic brain injury by mitigating oxidative stress and inflammation via the Nrf2 signaling pathway.
Lupus serum IgG induces microglia activation through Fc fragment dependent way and modulated by B-cell activating factor.
MG53 attenuates lipopolysaccharide-induced neurotoxicity and neuroinflammation via inhibiting TLR4/NF-κB pathway in vitro and in vivo.
Maternal separation disturbs postnatal development of the medial prefrontal cortex and affects the number of neurons and glial cells in adolescent rats.
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.
Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats.
Involvement of Macrophage Inflammatory Protein-1 Family Members in the Development of Diabetic Neuropathy and Their Contribution to Effectiveness of Morphine.
Polydatin Prevents Lipopolysaccharide (LPS)-Induced Parkinson's Disease via Regulation of the AKT/GSK3β-Nrf2/NF-κB Signaling Axis.
Allograft Inflammatory Factor-1 Mediates Macrophage-Induced Impairment of Insulin Signaling in Adipocytes.
Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures.
Differential Regulation of Adhesion and Phagocytosis of Resting and Activated Microglia by Dopamine.
Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice.
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Meloxicam Improves Cognitive Impairment of Diabetic Rats through COX2-PGE2-EPs-cAMP/pPKA Pathway.
Pharmacological blockade of CXCR3 by (±)-NBI-74330 reduces neuropathic pain and enhances opioid effectiveness - Evidence from in vivo and in vitro studies.
Zaprinast diminished pain and enhanced opioid analgesia in a rat neuropathic pain model.
Beneficial Effects of Exercise Pretreatment in a Sporadic Alzheimer's Rat Model.
Combination Treatment with Methylene Blue and Hypothermia in Global Cerebral Ischemia.
A model to study complement involvement in experimental retinal degeneration.
CD4+ αβ T cell infiltration into the leptomeninges of lumbar dorsal roots contributes to the transition from acute to chronic mechanical allodynia after adult rat tibial nerve injuries.
Peiminine Protects Dopaminergic Neurons from Inflammation-Induced Cell Death by Inhibiting the ERK1/2 and NF-κB Signalling Pathways.
Early Postnatal Exposure to Airborne Fine Particulate Matter Induces Autism-like Phenotypes in Male Rats.
Notch Signaling Regulates Microglial Activation and Inflammatory Reactions in a Rat Model of Temporal Lobe Epilepsy.
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Glia maturation factor beta is required for reactive gliosis after traumatic brain injury in zebrafish.
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Role of allograft inflammatory factor-1 in bleomycin-induced lung fibrosis.
Lipopolysaccharide from Rhodobacter sphaeroides (TLR4 antagonist) attenuates hypersensitivity and modulates nociceptive factors.
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
Involvement of microglial cells in the antinociceptive effects of metamizol in a mouse model of neuropathic pain.
Upregulation of allograft inflammatory factor‑1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype.
Proteomic profiling of human decidual immune proteins during Toxoplasma gondii infection.
NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson's disease.
Blockade of P2X4 Receptors Inhibits Neuropathic Pain-Related Behavior by Preventing MMP-9 Activation and, Consequently, Pronociceptive Interleukin Release in a Rat Model.
Colony-stimulating factor-1-induced AIF1 expression in tumor-associated macrophages enhances the progression of hepatocellular carcinoma.
Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.
Ketamine Alleviates Depressive-Like Behaviors via Down-Regulating Inflammatory Cytokines Induced by Chronic Restraint Stress in Mice.
Intranasal Delivery of a Caspase-1 Inhibitor in the Treatment of Global Cerebral Ischemia.
The RS504393 Influences the Level of Nociceptive Factors and Enhances Opioid Analgesic Potency in Neuropathic Rats.
Licochalcone A Prevents the Loss of Dopaminergic Neurons by Inhibiting Microglial Activation in Lipopolysaccharide (LPS)-Induced Parkinson's Disease Models.
Spinal CCL1/CCR8 signaling interplay as a potential therapeutic target - Evidence from a mouse diabetic neuropathy model.
Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production.
Silk fibroin-Pellethane® cardiovascular patches: Effect of silk fibroin concentration on vascular remodeling in rat model.
Suppression of MyD88-dependent signaling alleviates neuropathic pain induced by peripheral nerve injury in the rat.
Fingolimod (FTY720) attenuates social deficits, learning and memory impairments, neuronal loss and neuroinflammation in the rat model of autism.
Antibody incubation at 37°C improves fluorescent immunolabeling in free-floating thick tissue sections.
Sarsasapogenin-AA13 ameliorates Aβ-induced cognitive deficits via improving neuroglial capacity on Aβ clearance and antiinflammation.
Adenosine production by brain cells.
CCR6 (CC Chemokine Receptor 6) Is Essential for the Migration of Detrimental Natural Interleukin-17-Producing γδ T Cells in Stroke.
Low-level laser therapy for beta amyloid toxicity in rat hippocampus.
Early start of progressive motor deficits in Line 61 α-synuclein transgenic mice.
Bexarotene protects against traumatic brain injury in mice partially through apolipoprotein E.
Vanillin Protects Dopaminergic Neurons against Inflammation-Mediated Cell Death by Inhibiting ERK1/2, P38 and the NF-κB Signaling Pathway.
Galangin Reduces the Loss of Dopaminergic Neurons in an LPS-Evoked Model of Parkinson's Disease in Rats.
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
Gypenoside Attenuates β Amyloid-Induced Inflammation in N9 Microglial Cells via SOCS1 Signaling.
Blockade of Toll-Like Receptors (TLR2, TLR4) Attenuates Pain and Potentiates Buprenorphine Analgesia in a Rat Neuropathic Pain Model.
Regulation and role of ERK phosphorylation in glial cells following a nigrostriatal pathway injury.
Trans-cinnamaldehyde improves memory impairment by blocking microglial activation through the destabilization of iNOS mRNA in mice challenged with lipopolysaccharide.
Participation of pro- and anti-nociceptive interleukins in botulinum toxin A-induced analgesia in a rat model of neuropathic pain.
Methylene Blue promotes cortical neurogenesis and ameliorates behavioral deficit after photothrombotic stroke in rats.
Impact of acquired and innate immunity on spinal cord ischemia and reperfusion injury.
Blockade of IL-18 signaling diminished neuropathic pain and enhanced the efficacy of morphine and buprenorphine.
Pharmacological kynurenine 3-monooxygenase enzyme inhibition significantly reduces neuropathic pain in a rat model.
Expression of allograft inflammatory factor-1 in peripheral blood monocytes and synovial membranes in patients with rheumatoid arthritis.
Beneficial properties of maraviroc on neuropathic pain development and opioid effectiveness in rats.
Treatment with a carbon monoxide-releasing molecule (CORM-2) inhibits neuropathic pain and enhances opioid effectiveness in rats.
Intrathecal Injection of Human Umbilical Cord-Derived Mesenchymal Stem Cells Ameliorates Neuropathic Pain in Rats.
Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy.
NOD2 is involved in the inflammatory response after cerebral ischemia-reperfusion injury and triggers NADPH oxidase 2-derived reactive oxygen species.
Intervention with exercise restores motor deficits but not nigrostriatal loss in a progressive MPTP mouse model of Parkinson's disease.
Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson's disease models are mediated by GPR109A-dependent mechanisms.
The influence of microglia activation on the efficacy of amitriptyline, doxepin, milnacipran, venlafaxine and fluoxetine in a rat model of neuropathic pain.
Targeting the CD80/CD86 costimulatory pathway with CTLA4-Ig directs microglia toward a repair phenotype and promotes axonal outgrowth.
Chronic Noise Exposure Acts Cumulatively to Exacerbate Alzheimer's Disease-Like Amyloid-β Pathology and Neuroinflammation in the Rat Hippocampus.
Minocycline enhances the effectiveness of nociceptin/orphanin FQ during neuropathic pain.
Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy.
Photoreceptor degeneration, structural remodeling and glial activation: a morphological study on a genetic mouse model for pericyte deficiency.
Genetics of gene expression characterizes response to selective breeding for alcohol preference.
Cold-inducible RNA-binding protein mediates neuroinflammation in cerebral ischemia.
Peripheral immunomodulation with ginsenoside Rg1 ameliorates neuroinflammation-induced behavioral deficits in rats.
Involvement of pro- and antinociceptive factors in minocycline analgesia in rat neuropathic pain model.
Maternal bisphenol a diet induces anxiety-like behavior in female juvenile with neuroimmune activation.
Minocycline influences the anti-inflammatory interleukins and enhances the effectiveness of morphine under mice diabetic neuropathy.
ABT-702, an adenosine kinase inhibitor, attenuates inflammation in diabetic retinopathy.
Intraperitoneal administration of AAV9-shRNA inhibits target gene expression in the dorsal root ganglia of neonatal mice.
Time course and progression of wild type α-synuclein accumulation in a transgenic mouse model.
Effects of selective and non-selective inhibitors of nitric oxide synthase on morphine- and endomorphin-1-induced analgesia in acute and neuropathic pain in rats.
Involvement of extraneural tissues and upregulation of inducible nitric oxide synthase after experimental infection with rabies virus in BALB/c mice and LEW/SsN rats.
The dynamic expression of allograft inflammatory factor-1 in hepatic tissues and splenic cells of BALB/c mice with Schistosoma japonicum infection.
Daintain/AIF-1 promotes breast cancer cell migration by up-regulated TNF-α via activate p38 MAPK signaling pathway.
17β-Estradiol increased the expression of daintain/AIF-1 in RAW264.7 macrophages.
Li XX, Lang XY, Ren TT, Wang J, Lan R, Qin XY
Journal of ethnopharmacology 2022 Jan 10;282:114606
Journal of ethnopharmacology 2022 Jan 10;282:114606
Gut Microbiota Disorders Promote Inflammation and Aggravate Spinal Cord Injury Through the TLR4/MyD88 Signaling Pathway.
Rong Z, Huang Y, Cai H, Chen M, Wang H, Liu G, Zhang Z, Wu J
Frontiers in nutrition 2021;8:702659
Frontiers in nutrition 2021;8:702659
NU9056, a KAT 5 Inhibitor, Treatment Alleviates Brain Dysfunction by Inhibiting NLRP3 Inflammasome Activation, Affecting Gut Microbiota, and Derived Metabolites in LPS-Treated Mice.
Chen L, Qing W, Yi Z, Lin G, Peng Q, Zhou F
Frontiers in nutrition 2021;8:701760
Frontiers in nutrition 2021;8:701760
Rufinamide (RUF) suppresses inflammation and maintains the integrity of the blood-brain barrier during kainic acid-induced brain damage.
Yu H, He B, Han X, Yan T
Open life sciences 2021;16(1):845-855
Open life sciences 2021;16(1):845-855
Novel Scalable and Simplified System to Generate Microglia-Containing Cerebral Organoids From Human Induced Pluripotent Stem Cells.
Bodnar B, Zhang Y, Liu J, Lin Y, Wang P, Wei Z, Saribas S, Zhu Y, Li F, Wang X, Yang W, Li Q, Ho WZ, Hu W
Frontiers in cellular neuroscience 2021;15:682272
Frontiers in cellular neuroscience 2021;15:682272
Isoliquiritigenin Confers Neuroprotection and Alleviates Amyloid-β42-Induced Neuroinflammation in Microglia by Regulating the Nrf2/NF-κB Signaling.
Fu Y, Jia J
Frontiers in neuroscience 2021;15:638772
Frontiers in neuroscience 2021;15:638772
Class IIa HDAC Downregulation Contributes to Surgery-Induced Cognitive Impairment Through HMGB1-Mediated Inflammatory Response in the Hippocampi of Aged Mice.
Huang CM, Cai JJ, Jin SW, Lin QC, Fang QJ, Nan K, Han Y, Ge WW, Liu Y, Tao YX, Cao H, Li J
Journal of inflammation research 2021;14:2301-2315
Journal of inflammation research 2021;14:2301-2315
Traumatic Brain Injury Accelerates the Onset of Cognitive Dysfunction and Aggravates Alzheimer's-Like Pathology in the Hippocampus by Altering the Phenotype of Microglia in the APP/PS1 Mouse Model.
Wu D, Kumal JPP, Lu X, Li Y, Mao D, Tang X, Nie M, Liu X, Sun L, Liu B, Zhang Y
Frontiers in neurology 2021;12:666430
Frontiers in neurology 2021;12:666430
Catalytic patch with redox Cr/CeO2 nanozyme of noninvasive intervention for brain trauma.
Zhang S, Liu Y, Sun S, Wang J, Li Q, Yan R, Gao Y, Liu H, Liu S, Hao W, Dai H, Liu C, Sun Y, Long W, Mu X, Zhang XD
Theranostics 2021;11(6):2806-2821
Theranostics 2021;11(6):2806-2821
Effects of prenatal photobiomodulation treatment on neonatal hypoxic ischemia in rat offspring.
Yang L, Dong Y, Wu C, Youngblood H, Li Y, Zong X, Li L, Xu T, Zhang Q
Theranostics 2021;11(3):1269-1294
Theranostics 2021;11(3):1269-1294
Edaravone attenuates cadmium-induced toxicity by inhibiting oxidative stress and inflammation in ICR mice.
Fan SR, Ren TT, Yun MY, Lan R, Qin XY
Neurotoxicology 2021 Sep;86:1-9
Neurotoxicology 2021 Sep;86:1-9
Nilotinib inhibits microglia-mediated neuroinflammation to protect against dopaminergic neuronal death in Parkinson's disease models.
Wu J, Xu X, Zheng L, Mo J, Jin X, Bao Y
International immunopharmacology 2021 Oct;99:108025
International immunopharmacology 2021 Oct;99:108025
Sleep disturbance induces depressive behaviors and neuroinflammation by altering the circadian oscillations of clock genes in rats.
Xing C, Zhou Y, Xu H, Ding M, Zhang Y, Zhang M, Hu M, Huang X, Song L
Neuroscience research 2021 Oct;171:124-132
Neuroscience research 2021 Oct;171:124-132
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Lu Y, Hao R, Hu Y, Wei Y, Xie Y, Shen Y, Rui Q, Yu G
Chemico-biological interactions 2021 Oct 1;348:109653
Chemico-biological interactions 2021 Oct 1;348:109653
Bioinformatics analysis identifies CSF1R as an essential gene mediating Neuropathic pain - Experimental research.
Xu C, Zheng H, Liu T, Zhang Y, Feng Y
International journal of surgery (London, England) 2021 Nov;95:106140
International journal of surgery (London, England) 2021 Nov;95:106140
Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway.
Hao W, Hao C, Wu C, Xu Y, Wu S, Lu X, Yang J, Jin C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112591
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112591
Neuroprotective effects of liraglutide against inflammation through the AMPK/NF-κB pathway in a mouse model of Parkinson's disease.
Cao B, Zhang Y, Chen J, Wu P, Dong Y, Wang Y
Metabolic brain disease 2021 Nov 24;
Metabolic brain disease 2021 Nov 24;
TC10, a Rho family GTPase, is required for efficient axon regeneration in a neuron-autonomous manner.
Koinuma S, Negishi R, Nomura R, Sato K, Kojima T, Segi-Nishida E, Goitsuka R, Iwakura Y, Wada N, Koriyama Y, Kiryu-Seo S, Kiyama H, Nakamura T
Journal of neurochemistry 2021 May;157(4):1196-1206
Journal of neurochemistry 2021 May;157(4):1196-1206
A diet high in sugar and fat influences neurotransmitter metabolism and then affects brain function by altering the gut microbiota.
Guo Y, Zhu X, Zeng M, Qi L, Tang X, Wang D, Zhang M, Xie Y, Li H, Yang X, Chen D
Translational psychiatry 2021 May 27;11(1):328
Translational psychiatry 2021 May 27;11(1):328
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Wu X, Sheng H, Wang L, Xia P, Wang Y, Yu L, Lv W, Hu J
Aging 2021 Mar 26;13(7):10034-10057
Aging 2021 Mar 26;13(7):10034-10057
Protective effects of melatonin on the white matter damage of neonatal rats by regulating NLRP3 inflammasome activity.
Qin M, Liu Y, Sun M, Li X, Xu J, Zhang L, Jiang H
Neuroreport 2021 Jun 9;32(9):739-747
Neuroreport 2021 Jun 9;32(9):739-747
Edaravone attenuates H2O2 or glutamate-induced toxicity in hippocampal neurons and improves AlCl3/D-galactose induced cognitive impairment in mice.
Wu HT, Yu Y, Li XX, Lang XY, Gu RZ, Fan SR, Fang X, Bai JP, Lan R, Qin XY
Neurotoxicology 2021 Jul;85:68-78
Neurotoxicology 2021 Jul;85:68-78
Blocking Hepatoma-Derived Growth Factor Attenuates Vasospasm and Neuron Cell Apoptosis in Rats Subjected to Subarachnoid Hemorrhage.
Chung CL, Wu CH, Huang YH, Wu SC, Chai CY, Tsai HP, Kwan AL
Translational stroke research 2021 Jul 5;
Translational stroke research 2021 Jul 5;
Increased Expression of Thymic Stromal Lymphopoietin in Chronic Constriction Injury of Rat Nerve.
Wu CH, Lu CC, Huang CL, Wu MK, Lu YY
International journal of molecular sciences 2021 Jul 1;22(13)
International journal of molecular sciences 2021 Jul 1;22(13)
Minocycline alleviates depression-like symptoms by rescuing decrease in neurogenesis in dorsal hippocampus via blocking microglia activation/phagocytosis.
Bassett B, Subramaniyam S, Fan Y, Varney S, Pan H, Carneiro AMD, Chung CY
Brain, behavior, and immunity 2021 Jan;91:519-530
Brain, behavior, and immunity 2021 Jan;91:519-530
Role of lipocalin-2 in extracellular peroxiredoxin 2-induced brain swelling, inflammation and neuronal death.
Zhang J, Novakovic N, Hua Y, Keep RF, Xi G
Experimental neurology 2021 Jan;335:113521
Experimental neurology 2021 Jan;335:113521
Adrenomedullin 2 attenuates LPS-induced inflammation in microglia cells by receptor-mediated cAMP-PKA pathway.
Sun J, Qian P, Kang Y, Dai HB, Wang FZ, Wang HY, Zhou H, Gao Q, Zhou YB
Neuropeptides 2021 Feb;85:102109
Neuropeptides 2021 Feb;85:102109
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Wang C, Xu T, Lachance BB, Zhong X, Shen G, Xu T, Tang C, Jia X
Journal of neuroinflammation 2021 Feb 18;18(1):50
Journal of neuroinflammation 2021 Feb 18;18(1):50
Annexin A1 Attenuates Neutrophil Migration and IL-6 Expression through Fpr2 in a Mouse Model of Streptococcus suis-Induced Meningitis.
Ni C, Gao S, Zheng Y, Liu P, Zhai Y, Huang W, Jiang H, Lv Q, Kong D, Jiang Y
Infection and immunity 2021 Feb 16;89(3)
Infection and immunity 2021 Feb 16;89(3)
Gisenoside Rg1 attenuates cadmium-induced neurotoxicity in vitro and in vivo by attenuating oxidative stress and inflammation.
Ren TT, Yang JY, Wang J, Fan SR, Lan R, Qin XY
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2021 Dec;70(10-12):1151-1164
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2021 Dec;70(10-12):1151-1164
Schizandrin A ameliorates cognitive functions via modulating microglial polarisation in Alzheimer's disease mice.
Wang Q, Liu L, Guan H, Zhou Y, Li Q
Pharmaceutical biology 2021 Dec;59(1):860-867
Pharmaceutical biology 2021 Dec;59(1):860-867
Integration of Raman spectra with transcriptome data in glioblastoma multiforme defines tumour subtypes and predicts patient outcome.
Le Reste PJ, Pilalis E, Aubry M, McMahon M, Cano L, Etcheverry A, Chatziioannou A, Chevet E, Fautrel A
Journal of cellular and molecular medicine 2021 Dec;25(23):10846-10856
Journal of cellular and molecular medicine 2021 Dec;25(23):10846-10856
Axl Alleviates Neuroinflammation and Delays Japanese Encephalitis Progression in Mice.
Wang ZY, Zhen ZD, Fan DY, Wang PG, An J
Virologica Sinica 2021 Aug;36(4):667-677
Virologica Sinica 2021 Aug;36(4):667-677
8-Formylophiopogonanone B antagonizes doxorubicin-induced cardiotoxicity by suppressing heme oxygenase-1-dependent myocardial inflammation and fibrosis.
Qin D, Yue R, Deng P, Wang X, Zheng Z, Lv M, Zhang Y, Pu J, Xu J, Liang Y, Pi H, Yu Z, Hu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111779
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111779
Reactive microglia enhance the transmission of exosomal α-synuclein via toll-like receptor 2.
Xia Y, Zhang G, Kou L, Yin S, Han C, Hu J, Wan F, Sun Y, Wu J, Li Y, Huang J, Xiong N, Zhang Z, Wang T
Brain : a journal of neurology 2021 Aug 17;144(7):2024-2037
Brain : a journal of neurology 2021 Aug 17;144(7):2024-2037
Phytogalactolipid dLGG Inhibits Mouse Melanoma Brain Metastasis through Regulating Oxylipin Activity and Re-Programming Macrophage Polarity in the Tumor Microenvironment.
Yang CC, Chang MT, Chang CK, Shyur LF
Cancers 2021 Aug 16;13(16)
Cancers 2021 Aug 16;13(16)
Phosphatase and Tensin Homolog Deleted on Chromosome Ten Knockdown Attenuates Cognitive Deficits by Inhibiting Neuroinflammation in a Mouse Model of Perioperative Neurocognitive Disorder.
Shen Y, Chen L, Zhang Y, Du J, Hu J, Bao H, Xing Y, Si Y
Neuroscience 2021 Aug 1;468:199-210
Neuroscience 2021 Aug 1;468:199-210
Injectable Gelatin Hydrogel Suppresses Inflammation and Enhances Functional Recovery in a Mouse Model of Intracerebral Hemorrhage.
Xu J, Duan Z, Qi X, Ou Y, Guo X, Zi L, Wei Y, Liu H, Ma L, Li H, You C, Tian M
Frontiers in bioengineering and biotechnology 2020;8:785
Frontiers in bioengineering and biotechnology 2020;8:785
Microglia TREM2: A Potential Role in the Mechanism of Action of Electroacupuncture in an Alzheimer's Disease Animal Model.
Li Y, Jiang J, Tang Q, Tian H, Wang S, Wang Z, Liu H, Yang J, Ren J
Neural plasticity 2020;2020:8867547
Neural plasticity 2020;2020:8867547
Nrf2 Ablation Promotes Alzheimer's Disease-Like Pathology in APP/PS1 Transgenic Mice: The Role of Neuroinflammation and Oxidative Stress.
Ren P, Chen J, Li B, Zhang M, Yang B, Guo X, Chen Z, Cheng H, Wang P, Wang S, Wang N, Zhang G, Wu X, Ma D, Guan D, Zhao R
Oxidative medicine and cellular longevity 2020;2020:3050971
Oxidative medicine and cellular longevity 2020;2020:3050971
Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia.
He XM, Zhou YZ, Sheng S, Li JJ, Wang GQ, Zhang F
Oxidative medicine and cellular longevity 2020;2020:2963540
Oxidative medicine and cellular longevity 2020;2020:2963540
Resveratrol Preincubation Enhances the Therapeutic Efficacy of hUC-MSCs by Improving Cell Migration and Modulating Neuroinflammation Mediated by MAPK Signaling in a Mouse Model of Alzheimer's Disease.
Wang X, Wu J, Ma S, Xie Y, Liu H, Yao M, Zhang Y, Yang GL, Yang B, Guo R, Guan F
Frontiers in cellular neuroscience 2020;14:62
Frontiers in cellular neuroscience 2020;14:62
Kalirin-7 contributes to type 2 diabetic neuropathic pain via the postsynaptic density-95/N-methyl-D-aspartate receptor 2B-dependent N-methyl-D-aspartate receptor 2B phosphorylation in the spinal cord in rats.
Lu JH, Zhang MB, Wang JW, Ye XY, Chen JL, Jia GL, Xie CS, Shen YJ, Tao YX, Li J, Cao H
American journal of translational research 2020;12(8):4819-4829
American journal of translational research 2020;12(8):4819-4829
Caveolin-1 in spinal cord modulates type-2 diabetic neuropathic pain through the Rac1/NOX2/NR2B signaling pathway.
Chen JL, Lu JH, Xie CS, Shen YJ, Wang JW, Ye XY, Zhang MB, Jia GL, Tao YX, Li J, Cao H
American journal of translational research 2020;12(5):1714-1727
American journal of translational research 2020;12(5):1714-1727
FTY720 Prevents Spatial Memory Impairment in a Rat Model of Chronic Cerebral Hypoperfusion via a SIRT3-Independent Pathway.
Zhang M, Hu Y, Zhang J, Zhang J
Frontiers in aging neuroscience 2020;12:593364
Frontiers in aging neuroscience 2020;12:593364
LongShengZhi Capsule Attenuates Alzheimer-Like Pathology in APP/PS1 Double Transgenic Mice by Reducing Neuronal Oxidative Stress and Inflammation.
Yin Z, Wang X, Zheng S, Cao P, Chen Y, Yu M, Liao C, Zhang Z, Han J, Duan Y, Yang X, Zhang S
Frontiers in aging neuroscience 2020;12:582455
Frontiers in aging neuroscience 2020;12:582455
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
Yu Y, Wu DM, Li J, Deng SH, Liu T, Zhang T, He M, Zhao YY, Xu Y
Frontiers in immunology 2020;11:593368
Frontiers in immunology 2020;11:593368
Glucagon-like peptide-1 receptor agonist Exendin-4 improves neurological outcomes by attenuating TBI- induced inflammatory responses and MAPK activation in rats.
Zhang J, Yi T, Cheng S, Zhang S
International immunopharmacology 2020 Sep;86:106715
International immunopharmacology 2020 Sep;86:106715
MSC-derived exosomes promote recovery from traumatic brain injury via microglia/macrophages in rat.
Chen Y, Li J, Ma B, Li N, Wang S, Sun Z, Xue C, Han Q, Wei J, Zhao RC
Aging 2020 Sep 23;12(18):18274-18296
Aging 2020 Sep 23;12(18):18274-18296
MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis.
Ma S, Wang Y, Zhou X, Li Z, Zhang Z, Wang Y, Huang T, Zhang Y, Shi J, Guan F
ACS chemical neuroscience 2020 Sep 2;11(17):2590-2601
ACS chemical neuroscience 2020 Sep 2;11(17):2590-2601
Metamizole relieves pain by influencing cytokine levels in dorsal root ganglia in a rat model of neuropathic pain.
Zajaczkowska R, Kwiatkowski K, Pawlik K, Piotrowska A, Rojewska E, Makuch W, Wordliczek J, Mika J
Pharmacological reports : PR 2020 Oct;72(5):1310-1322
Pharmacological reports : PR 2020 Oct;72(5):1310-1322
Neuroprotective mechanism of L-cysteine after subarachnoid hemorrhage.
Xiong Y, Xin DQ, Hu Q, Wang LX, Qiu J, Yuan HT, Chu XL, Liu DX, Li G, Wang Z
Neural regeneration research 2020 Oct;15(10):1920-1930
Neural regeneration research 2020 Oct;15(10):1920-1930
IL-1β/IL-1R1 signaling induced by intranasal lipopolysaccharide infusion regulates alpha-Synuclein pathology in the olfactory bulb, substantia nigra and striatum.
Niu H, Wang Q, Zhao W, Liu J, Wang D, Muhammad B, Liu X, Quan N, Zhang H, Zhang F, Wang Y, Li H, Yang R
Brain pathology (Zurich, Switzerland) 2020 Nov;30(6):1102-1118
Brain pathology (Zurich, Switzerland) 2020 Nov;30(6):1102-1118
Morphological analyzes of microglia heterogeneity and dynamics during photoreceptor degeneration in vitro: Presumptive dark microglia in porcine retina.
Johansson K, Svensson LA, Mohlin C
Experimental eye research 2020 Nov;200:108217
Experimental eye research 2020 Nov;200:108217
Attenuation of Acute Intracerebral Hemorrhage-Induced Microglial Activation and Neuronal Death Mediated by the Blockade of Metabotropic Glutamate Receptor 5 In Vivo.
Rahman MS, Yang J, Luan Y, Qiu Z, Zhang J, Lu H, Chen X, Liu Y
Neurochemical research 2020 May;45(5):1230-1243
Neurochemical research 2020 May;45(5):1230-1243
Changes in macrophage inflammatory protein-1 (MIP-1) family members expression induced by traumatic brain injury in mice.
Ciechanowska A, Popiolek-Barczyk K, Pawlik K, Ciapała K, Oggioni M, Mercurio D, De Simoni MG, Mika J
Immunobiology 2020 May;225(3):151911
Immunobiology 2020 May;225(3):151911
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype.
Hou B, Zhang Y, Liang P, He Y, Peng B, Liu W, Han S, Yin J, He X
Cell death & disease 2020 May 15;11(5):377
Cell death & disease 2020 May 15;11(5):377
Carbon dot targeting to nitrogen signaling molecules for inhibiting neuronal death.
Ouyang L, Mu X, Wang J, Li Q, Gao Y, Liu H, Sun S, Ren Q, Yan R, Wang J, Liu Q, Sun Y, Liu C, He H, Long W, Zhang XD
Journal of materials chemistry. B 2020 Mar 18;8(11):2321-2330
Journal of materials chemistry. B 2020 Mar 18;8(11):2321-2330
Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity.
Zong X, Dong Y, Li Y, Yang L, Li Y, Yang B, Tucker L, Zhao N, Brann DW, Yan X, Hu S, Zhang Q
Translational stroke research 2020 Jun;11(3):450-467
Translational stroke research 2020 Jun;11(3):450-467
The effect of swimming exercise and diet on the hypothalamic inflammation of ApoE-/- mice based on SIRT1-NF-κB-GnRH expression.
Wang X, Yang J, Lu T, Zhan Z, Wei W, Lyu X, Jiang Y, Xue X
Aging 2020 Jun 9;12(11):11085-11099
Aging 2020 Jun 9;12(11):11085-11099
Natural Xanthone α-Mangostin Inhibits LPS-Induced Microglial Inflammatory Responses and Memory Impairment by Blocking the TAK1/NF-κB Signaling Pathway.
Guan H, Li J, Tan X, Luo S, Liu Y, Meng Y, Wu B, Zhou Y, Yang Y, Chen H, Hou L, Qiu Y, Li J
Molecular nutrition & food research 2020 Jul;64(14):e2000096
Molecular nutrition & food research 2020 Jul;64(14):e2000096
Over-Expression of Allograft Inflammatory Factor-1 (AIF-1) in Patients with Rheumatoid Arthritis.
Piotrowska K, Słuczanowska-Głabowska S, Kurzawski M, Dziedziejko V, Kopytko P, Paczkowska E, Rogińska D, Safranow K, Machaliński B, Pawlik A
Biomolecules 2020 Jul 16;10(7)
Biomolecules 2020 Jul 16;10(7)
Chemokine CCL2 contributes to BBB disruption via the p38 MAPK signaling pathway following acute intracerebral hemorrhage.
Guo F, Xu D, Lin Y, Wang G, Wang F, Gao Q, Wei Q, Lei S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1872-1884
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1872-1884
BHBA treatment improves cognitive function by targeting pleiotropic mechanisms in transgenic mouse model of Alzheimer's disease.
Wu Y, Gong Y, Luan Y, Li Y, Liu J, Yue Z, Yuan B, Sun J, Xie C, Li L, Zhen J, Jin X, Zheng Y, Wang X, Xie L, Wang W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1412-1429
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1412-1429
Synaptic alterations and immune response are sexually dimorphic in a non-pertussis toxin model of experimental autoimmune encephalomyelitis.
Murphy KL, Fischer R, Swanson KA, Bhatt IJ, Oakley L, Smeyne R, Bracchi-Ricard V, Bethea JR
Experimental neurology 2020 Jan;323:113061
Experimental neurology 2020 Jan;323:113061
Scorpion alleviates bone cancer pain through inhibition of bone destruction and glia activation.
Yu J, Luo Y, Jin H, Lv J, Zhou T, Yabasin IB, Wen Q
Molecular pain 2020 Jan-Dec;16:1744806920909993
Molecular pain 2020 Jan-Dec;16:1744806920909993
Protective role of cinnabar and realgar in Hua-Feng-Dan against LPS plus rotenone-induced neurotoxicity and disturbance of gut microbiota in rats.
Chen C, Zhang BB, Hu AL, Li H, Liu J, Zhang F
Journal of ethnopharmacology 2020 Jan 30;247:112299
Journal of ethnopharmacology 2020 Jan 30;247:112299
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Xu B, Lang LM, Lian S, Guo JR, Wang JF, Liu J, Yang HM, Li SZ
Brain research 2020 Jan 1;1726:146495
Brain research 2020 Jan 1;1726:146495
Photobiomodulation therapy for repeated closed head injury in rats.
Yang B, Xu J, Li Y, Dong Y, Li Y, Tucker L, Yang L, Zong X, Wu C, Xu T, Hu S, Zhang Q, Yan X
Journal of biophotonics 2020 Feb;13(2):e201960117
Journal of biophotonics 2020 Feb;13(2):e201960117
Acetate attenuates perioperative neurocognitive disorders in aged mice.
Wen C, Xie T, Pan K, Deng Y, Zhao Z, Li N, Bian J, Deng X, Zha Y
Aging 2020 Feb 26;12(4):3862-3879
Aging 2020 Feb 26;12(4):3862-3879
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Lang L, Xu B, Yuan J, Li S, Lian S, Chen Y, Guo J, Yang H
International immunopharmacology 2020 Dec;89(Pt B):106908
International immunopharmacology 2020 Dec;89(Pt B):106908
Menthol protects dopaminergic neurons against inflammation-mediated damage in lipopolysaccharide (LPS)-Evoked model of Parkinson's disease.
Du J, Liu D, Zhang X, Zhou A, Su Y, He D, Fu S, Gao F
International immunopharmacology 2020 Aug;85:106679
International immunopharmacology 2020 Aug;85:106679
Glutathione Depletion and Parkinsonian Neurotoxin MPP+-Induced TRPM2 Channel Activation Play Central Roles in Oxidative Cytotoxicity and Inflammation in Microglia.
Yıldızhan K, Nazıroğlu M
Molecular neurobiology 2020 Aug;57(8):3508-3525
Molecular neurobiology 2020 Aug;57(8):3508-3525
Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition.
Fan X, Elkin K, Shi Y, Zhang Z, Cheng Y, Gu J, Liang J, Wang C, Ji X
Neurological research 2020 Aug;42(8):693-702
Neurological research 2020 Aug;42(8):693-702
CCR4 antagonist (C021) influences the level of nociceptive factors and enhances the analgesic potency of morphine in a rat model of neuropathic pain.
Bogacka J, Popiolek-Barczyk K, Pawlik K, Ciechanowska A, Makuch W, Rojewska E, Dobrogowski J, Przeklasa-Muszynska A, Mika J
European journal of pharmacology 2020 Aug 5;880:173166
European journal of pharmacology 2020 Aug 5;880:173166
Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages.
Wang ZY, Zhen ZD, Fan DY, Qin CF, Han DS, Zhou HN, Wang PG, An J
Journal of virology 2020 Aug 17;94(17)
Journal of virology 2020 Aug 17;94(17)
Cu(II) disrupts autophagy-mediated lysosomal degradation of oligomeric Aβ in microglia via mTOR-TFEB pathway.
Tan X, Guan H, Yang Y, Luo S, Hou L, Chen H, Li J
Toxicology and applied pharmacology 2020 Aug 15;401:115090
Toxicology and applied pharmacology 2020 Aug 15;401:115090
Mefenamic acid can attenuate depressive symptoms by suppressing microglia activation induced upon chronic stress.
Feng X, Fan Y, Chung CY
Brain research 2020 Aug 1;1740:146846
Brain research 2020 Aug 1;1740:146846
Sirtuin 2 Inhibition Attenuates Sevoflurane-Induced Learning and Memory Deficits in Developing Rats via Modulating Microglial Activation.
Wu Z, Zhang Y, Zhang Y, Zhao P
Cellular and molecular neurobiology 2020 Apr;40(3):437-446
Cellular and molecular neurobiology 2020 Apr;40(3):437-446
The blockade of CC chemokine receptor type 1 influences the level of nociceptive factors and enhances opioid analgesic potency in a rat model of neuropathic pain.
Pawlik K, Piotrowska A, Kwiatkowski K, Ciapała K, Popiolek-Barczyk K, Makuch W, Mika J
Immunology 2020 Apr;159(4):413-428
Immunology 2020 Apr;159(4):413-428
Intracerebral Hemorrhage-Induced Brain Injury in Rats: the Role of Extracellular Peroxiredoxin 2.
Bian L, Zhang J, Wang M, Keep RF, Xi G, Hua Y
Translational stroke research 2020 Apr;11(2):288-295
Translational stroke research 2020 Apr;11(2):288-295
Interferon-λ Attenuates Rabies Virus Infection by Inducing Interferon-Stimulated Genes and Alleviating Neurological Inflammation.
Li Y, Zhao L, Luo Z, Zhang Y, Lv L, Zhao J, Sui B, Huang F, Cui M, Fu ZF, Zhou M
Viruses 2020 Apr 6;12(4)
Viruses 2020 Apr 6;12(4)
H2S attenuates injury after ischemic stroke by diminishing the assembly of CaMKII with ASK1-MKK3-p38 signaling module.
Song YJ, Shi Y, Cui MM, Li M, Wen XR, Zhou XY, Lou HQ, Wang YL, Qi DS, Tang M, Zhang XB
Behavioural brain research 2020 Apr 20;384:112520
Behavioural brain research 2020 Apr 20;384:112520
Exosomes Derived From Bone Marrow Mesenchymal Stem Cells Inhibit Complement Activation In Rats With Spinal Cord Injury.
Zhao C, Zhou X, Qiu J, Xin D, Li T, Chu X, Yuan H, Wang H, Wang Z, Wang D
Drug design, development and therapy 2019;13:3693-3704
Drug design, development and therapy 2019;13:3693-3704
Expression of cysteinyl leukotriene receptor in brain tissues of rats with Streptococcus pneumoniae meningitis.
Yu S, Yan J, Chen X, Zhu X, Li X, Liao L
International journal of clinical and experimental pathology 2019;12(12):4242-4252
International journal of clinical and experimental pathology 2019;12(12):4242-4252
Naringenin Produces Neuroprotection Against LPS-Induced Dopamine Neurotoxicity via the Inhibition of Microglial NLRP3 Inflammasome Activation.
Chen C, Wei YZ, He XM, Li DD, Wang GQ, Li JJ, Zhang F
Frontiers in immunology 2019;10:936
Frontiers in immunology 2019;10:936
Pharmacological Blockade of Spinal CXCL3/CXCR2 Signaling by NVP CXCR2 20, a Selective CXCR2 Antagonist, Reduces Neuropathic Pain Following Peripheral Nerve Injury.
Piotrowska A, Rojewska E, Pawlik K, Kreiner G, Ciechanowska A, Makuch W, Nalepa I, Mika J
Frontiers in immunology 2019;10:2198
Frontiers in immunology 2019;10:2198
Ghrelin Attenuates Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis Involving NLRP3 Inflammasome Signaling Pathway and Pyroptosis.
Liu F, Li Z, He X, Yu H, Feng J
Frontiers in pharmacology 2019;10:1320
Frontiers in pharmacology 2019;10:1320
Melatonin alleviates cognition impairment by antagonizing brain insulin resistance in aged rats fed a high-fat diet.
Xu J, Gao H, Zhang L, Rong S, Yang W, Ma C, Chen M, Huang Q, Deng Q, Huang F
Journal of pineal research 2019 Sep;67(2):e12584
Journal of pineal research 2019 Sep;67(2):e12584
Intracerebroventricular administration of lupus serum induces microglia activation and leukocyte adhesion in the cerebromicrovasculature of mice.
Wang X, Li Y, Wang Y, Feng Q, Yang P, Qin L
Journal of neuroimmunology 2019 Sep 15;334:576994
Journal of neuroimmunology 2019 Sep 15;334:576994
Antinociceptive effect of isoorientin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Zhang G, Liu N, Zhu C, Ma L, Yang J, Du J, Zhang W, Sun T, Niu J, Yu J
International immunopharmacology 2019 Oct;75:105753
International immunopharmacology 2019 Oct;75:105753
Farrerol protects dopaminergic neurons in a rat model of lipopolysaccharide-induced Parkinson's disease by suppressing the activation of the AKT and NF-κB signaling pathways.
Li Y, Zeng Y, Meng T, Gao X, Huang B, He D, Ran X, Du J, Zhang Y, Fu S, Hu G
International immunopharmacology 2019 Oct;75:105739
International immunopharmacology 2019 Oct;75:105739
Nanozyme-Based Bandage with Single-Atom Catalysis for Brain Trauma.
Yan R, Sun S, Yang J, Long W, Wang J, Mu X, Li Q, Hao W, Zhang S, Liu H, Gao Y, Ouyang L, Chen J, Liu S, Zhang XD, Ming D
ACS nano 2019 Oct 22;13(10):11552-11560
ACS nano 2019 Oct 22;13(10):11552-11560
TREM2 deficiency aggravates α-synuclein-induced neurodegeneration and neuroinflammation in Parkinson's disease models.
Guo Y, Wei X, Yan H, Qin Y, Yan S, Liu J, Zhao Y, Jiang F, Lou H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):12164-12174
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):12164-12174
Splicing repression is a major function of TDP-43 in motor neurons.
Donde A, Sun M, Ling JP, Braunstein KE, Pang B, Wen X, Cheng X, Chen L, Wong PC
Acta neuropathologica 2019 Nov;138(5):813-826
Acta neuropathologica 2019 Nov;138(5):813-826
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Shah SZA, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, Mangi MH, Wu W, Lai M, Zhang X, Duan Y, Wang L, Zhou X, Yang L
International journal of molecular sciences 2019 Mar 6;20(5)
International journal of molecular sciences 2019 Mar 6;20(5)
The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression.
Ma B, Cheng H, Mu C, Geng G, Zhao T, Luo Q, Ma K, Chang R, Liu Q, Gao R, Nie J, Xie J, Han J, Chen L, Ma G, Zhu Y, Chen Q
Nature communications 2019 Mar 4;10(1):1034
Nature communications 2019 Mar 4;10(1):1034
Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1.
Yousef H, Czupalla CJ, Lee D, Chen MB, Burke AN, Zera KA, Zandstra J, Berber E, Lehallier B, Mathur V, Nair RV, Bonanno LN, Yang AC, Peterson T, Hadeiba H, Merkel T, Körbelin J, Schwaninger M, Buckwalter MS, Quake SR, Butcher EC, Wyss-Coray T
Nature medicine 2019 Jun;25(6):988-1000
Nature medicine 2019 Jun;25(6):988-1000
Complement Inhibition Attenuates Early Erythrolysis in the Hematoma and Brain Injury in Aged Rats.
Wang M, Hua Y, Keep RF, Wan S, Novakovic N, Xi G
Stroke 2019 Jul;50(7):1859-1868
Stroke 2019 Jul;50(7):1859-1868
Naringenin targets on astroglial Nrf2 to support dopaminergic neurons.
Wang GQ, Zhang B, He XM, Li DD, Shi JS, Zhang F
Pharmacological research 2019 Jan;139:452-459
Pharmacological research 2019 Jan;139:452-459
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Zhu BL, Long Y, Luo W, Yan Z, Lai YJ, Zhao LG, Zhou WH, Wang YJ, Shen LL, Liu L, Deng XJ, Wang XF, Sun F, Chen GJ
Brain : a journal of neurology 2019 Jan 1;142(1):176-192
Brain : a journal of neurology 2019 Jan 1;142(1):176-192
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Xu B, Zang SC, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM, Lian S
Brain, behavior, and immunity 2019 Feb;76:223-235
Brain, behavior, and immunity 2019 Feb;76:223-235
Redox Trimetallic Nanozyme with Neutral Environment Preference for Brain Injury.
Mu X, Wang J, Li Y, Xu F, Long W, Ouyang L, Liu H, Jing Y, Wang J, Dai H, Liu Q, Sun Y, Liu C, Zhang XD
ACS nano 2019 Feb 26;13(2):1870-1884
ACS nano 2019 Feb 26;13(2):1870-1884
Microglia as modulators of exosomal alpha-synuclein transmission.
Xia Y, Zhang G, Han C, Ma K, Guo X, Wan F, Kou L, Yin S, Liu L, Huang J, Xiong N, Wang T
Cell death & disease 2019 Feb 20;10(3):174
Cell death & disease 2019 Feb 20;10(3):174
Melatonin receptor activation provides cerebral protection after traumatic brain injury by mitigating oxidative stress and inflammation via the Nrf2 signaling pathway.
Wang J, Jiang C, Zhang K, Lan X, Chen X, Zang W, Wang Z, Guan F, Zhu C, Yang X, Lu H, Wang J
Free radical biology & medicine 2019 Feb 1;131:345-355
Free radical biology & medicine 2019 Feb 1;131:345-355
Lupus serum IgG induces microglia activation through Fc fragment dependent way and modulated by B-cell activating factor.
Yang C, Hou X, Feng Q, Li Y, Wang X, Qin L, Yang P
Journal of translational medicine 2019 Dec 21;17(1):426
Journal of translational medicine 2019 Dec 21;17(1):426
MG53 attenuates lipopolysaccharide-induced neurotoxicity and neuroinflammation via inhibiting TLR4/NF-κB pathway in vitro and in vivo.
Guan F, Zhou X, Li P, Wang Y, Liu M, Li F, Cui Y, Huang T, Yao M, Zhang Y, Ma J, Ma S
Progress in neuro-psychopharmacology & biological psychiatry 2019 Dec 20;95:109684
Progress in neuro-psychopharmacology & biological psychiatry 2019 Dec 20;95:109684
Maternal separation disturbs postnatal development of the medial prefrontal cortex and affects the number of neurons and glial cells in adolescent rats.
Majcher-Maślanka I, Solarz A, Chocyk A
Neuroscience 2019 Dec 15;423:131-147
Neuroscience 2019 Dec 15;423:131-147
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Xu B, Lang LM, Li SZ, Guo JR, Wang JF, Yang HM, Lian S
Biomolecules 2019 Aug 30;9(9)
Biomolecules 2019 Aug 30;9(9)
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.
Zhang B, Wang G, He J, Yang Q, Li D, Li J, Zhang F
Journal of neuroinflammation 2019 Apr 22;16(1):92
Journal of neuroinflammation 2019 Apr 22;16(1):92
Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats.
Fan J, Chen M, Wang X, Tian Z, Wang J, Fan D, Zeng J, Zhang K, Dai X
Toxicological sciences : an official journal of the Society of Toxicology 2019 Apr 1;168(2):381-393
Toxicological sciences : an official journal of the Society of Toxicology 2019 Apr 1;168(2):381-393
Involvement of Macrophage Inflammatory Protein-1 Family Members in the Development of Diabetic Neuropathy and Their Contribution to Effectiveness of Morphine.
Rojewska E, Zychowska M, Piotrowska A, Kreiner G, Nalepa I, Mika J
Frontiers in immunology 2018;9:494
Frontiers in immunology 2018;9:494
Polydatin Prevents Lipopolysaccharide (LPS)-Induced Parkinson's Disease via Regulation of the AKT/GSK3β-Nrf2/NF-κB Signaling Axis.
Huang B, Liu J, Meng T, Li Y, He D, Ran X, Chen G, Guo W, Kan X, Fu S, Wang W, Liu D
Frontiers in immunology 2018;9:2527
Frontiers in immunology 2018;9:2527
Allograft Inflammatory Factor-1 Mediates Macrophage-Induced Impairment of Insulin Signaling in Adipocytes.
Ren J, Lin Y, Tang J, Yue H, Zhao Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(1):403-413
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(1):403-413
Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures.
Zhang B, Wei YZ, Wang GQ, Li DD, Shi JS, Zhang F
Frontiers in cellular neuroscience 2018;12:531
Frontiers in cellular neuroscience 2018;12:531
Differential Regulation of Adhesion and Phagocytosis of Resting and Activated Microglia by Dopamine.
Fan Y, Chen Z, Pathak JL, Carneiro AMD, Chung CY
Frontiers in cellular neuroscience 2018;12:309
Frontiers in cellular neuroscience 2018;12:309
Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice.
Zuo Y, Wang J, Liao F, Yan X, Li J, Huang L, Liu F
Frontiers in molecular neuroscience 2018;11:401
Frontiers in molecular neuroscience 2018;11:401
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Xu B, Lian S, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM
Brain research bulletin 2018 Sep;142:163-175
Brain research bulletin 2018 Sep;142:163-175
Meloxicam Improves Cognitive Impairment of Diabetic Rats through COX2-PGE2-EPs-cAMP/pPKA Pathway.
Li H, Luo Y, Xu Y, Yang L, Hu C, Chen Q, Yang Y, Ma J, Zhang J, Xia H, Li Y, Yang J
Molecular pharmaceutics 2018 Sep 4;15(9):4121-4131
Molecular pharmaceutics 2018 Sep 4;15(9):4121-4131
Pharmacological blockade of CXCR3 by (±)-NBI-74330 reduces neuropathic pain and enhances opioid effectiveness - Evidence from in vivo and in vitro studies.
Piotrowska A, Rojewska E, Pawlik K, Kreiner G, Ciechanowska A, Makuch W, Zychowska M, Mika J
Biochimica et biophysica acta. Molecular basis of disease 2018 Oct;1864(10):3418-3437
Biochimica et biophysica acta. Molecular basis of disease 2018 Oct;1864(10):3418-3437
Zaprinast diminished pain and enhanced opioid analgesia in a rat neuropathic pain model.
Rojewska E, Piotrowska A, Jurga A, Makuch W, Mika J
European journal of pharmacology 2018 Nov 15;839:21-32
European journal of pharmacology 2018 Nov 15;839:21-32
Beneficial Effects of Exercise Pretreatment in a Sporadic Alzheimer's Rat Model.
Wu C, Yang L, Tucker D, Dong Y, Zhu L, Duan R, Liu TC, Zhang Q
Medicine and science in sports and exercise 2018 May;50(5):945-956
Medicine and science in sports and exercise 2018 May;50(5):945-956
Combination Treatment with Methylene Blue and Hypothermia in Global Cerebral Ischemia.
Li L, Yang R, Li P, Lu H, Hao J, Li L, Tucker D, Zhang Q
Molecular neurobiology 2018 Mar;55(3):2042-2055
Molecular neurobiology 2018 Mar;55(3):2042-2055
A model to study complement involvement in experimental retinal degeneration.
Mohlin C, Sandholm K, Kvanta A, Ekdahl KN, Johansson K
Upsala journal of medical sciences 2018 Mar;123(1):28-42
Upsala journal of medical sciences 2018 Mar;123(1):28-42
CD4+ αβ T cell infiltration into the leptomeninges of lumbar dorsal roots contributes to the transition from acute to chronic mechanical allodynia after adult rat tibial nerve injuries.
Du B, Ding YQ, Xiao X, Ren HY, Su BY, Qi JG
Journal of neuroinflammation 2018 Mar 15;15(1):81
Journal of neuroinflammation 2018 Mar 15;15(1):81
Peiminine Protects Dopaminergic Neurons from Inflammation-Induced Cell Death by Inhibiting the ERK1/2 and NF-κB Signalling Pathways.
Chen G, Liu J, Jiang L, Ran X, He D, Li Y, Huang B, Wang W, Liu D, Fu S
International journal of molecular sciences 2018 Mar 12;19(3)
International journal of molecular sciences 2018 Mar 12;19(3)
Early Postnatal Exposure to Airborne Fine Particulate Matter Induces Autism-like Phenotypes in Male Rats.
Li K, Li L, Cui B, Gai Z, Li Q, Wang S, Yan J, Lin B, Tian L, Liu H, Liu X, Xi Z
Toxicological sciences : an official journal of the Society of Toxicology 2018 Mar 1;162(1):189-199
Toxicological sciences : an official journal of the Society of Toxicology 2018 Mar 1;162(1):189-199
Notch Signaling Regulates Microglial Activation and Inflammatory Reactions in a Rat Model of Temporal Lobe Epilepsy.
Wu L, Li Y, Yu M, Yang F, Tu M, Xu H
Neurochemical research 2018 Jun;43(6):1269-1282
Neurochemical research 2018 Jun;43(6):1269-1282
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Zhang J, Tucker LD, DongYan, Lu Y, Yang L, Wu C, Li Y, Zhang Q
Neurochemistry international 2018 Jun;116:1-12
Neurochemistry international 2018 Jun;116:1-12
Glia maturation factor beta is required for reactive gliosis after traumatic brain injury in zebrafish.
Yin G, Du M, Li R, Li K, Huang X, Duan D, Ai X, Yao F, Zhang L, Hu Z, Wu B
Experimental neurology 2018 Jul;305:129-138
Experimental neurology 2018 Jul;305:129-138
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, Zhang J, Liu TC, Zhang Q
Experimental neurology 2018 Jan;299(Pt A):86-96
Experimental neurology 2018 Jan;299(Pt A):86-96
Role of allograft inflammatory factor-1 in bleomycin-induced lung fibrosis.
Nagahara H, Seno T, Yamamoto A, Obayashi H, Inoue T, Kida T, Nakabayashi A, Kukida Y, Fujioka K, Fujii W, Murakami K, Kohno M, Kawahito Y
Biochemical and biophysical research communications 2018 Jan 8;495(2):1901-1907
Biochemical and biophysical research communications 2018 Jan 8;495(2):1901-1907
Lipopolysaccharide from Rhodobacter sphaeroides (TLR4 antagonist) attenuates hypersensitivity and modulates nociceptive factors.
Jurga AM, Rojewska E, Makuch W, Mika J
Pharmaceutical biology 2018 Dec;56(1):275-286
Pharmaceutical biology 2018 Dec;56(1):275-286
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
Wang B, Zhang G, Yang M, Liu N, Li YX, Ma H, Ma L, Sun T, Tan H, Yu J
Neurochemical research 2018 Dec;43(12):2404-2422
Neurochemical research 2018 Dec;43(12):2404-2422
Involvement of microglial cells in the antinociceptive effects of metamizol in a mouse model of neuropathic pain.
Zajaczkowska R, Popiolek-Barczyk K, Pilat D, Rojewska E, Makuch W, Wordliczek J, Mika J
Pharmacology, biochemistry, and behavior 2018 Dec;175:77-88
Pharmacology, biochemistry, and behavior 2018 Dec;175:77-88
Upregulation of allograft inflammatory factor‑1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype.
Li Y, Wang X, Zhang L, Yuan X, Hao J, Ni J, Hao L
International journal of molecular medicine 2018 Aug;42(2):861-872
International journal of molecular medicine 2018 Aug;42(2):861-872
Proteomic profiling of human decidual immune proteins during Toxoplasma gondii infection.
Zhang D, Sun X, Ren L, Yang C, Liu X, Zhang H, Jiang Y, Hu X
Journal of proteomics 2018 Aug 30;186:28-37
Journal of proteomics 2018 Aug 30;186:28-37
NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson's disease.
Cheng L, Chen L, Wei X, Wang Y, Ren Z, Zeng S, Zhang X, Wen H, Gao C, Liu H
Journal of neuroinflammation 2018 Aug 29;15(1):243
Journal of neuroinflammation 2018 Aug 29;15(1):243
Blockade of P2X4 Receptors Inhibits Neuropathic Pain-Related Behavior by Preventing MMP-9 Activation and, Consequently, Pronociceptive Interleukin Release in a Rat Model.
Jurga AM, Piotrowska A, Makuch W, Przewlocka B, Mika J
Frontiers in pharmacology 2017;8:48
Frontiers in pharmacology 2017;8:48
Colony-stimulating factor-1-induced AIF1 expression in tumor-associated macrophages enhances the progression of hepatocellular carcinoma.
Cai H, Zhu XD, Ao JY, Ye BG, Zhang YY, Chai ZT, Wang CH, Shi WK, Cao MQ, Li XL, Sun HC
Oncoimmunology 2017;6(9):e1333213
Oncoimmunology 2017;6(9):e1333213
Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.
Lu Y, Dong Y, Tucker D, Wang R, Ahmed ME, Brann D, Zhang Q
Journal of Alzheimer's disease : JAD 2017;56(4):1469-1484
Journal of Alzheimer's disease : JAD 2017;56(4):1469-1484
Ketamine Alleviates Depressive-Like Behaviors via Down-Regulating Inflammatory Cytokines Induced by Chronic Restraint Stress in Mice.
Tan S, Wang Y, Chen K, Long Z, Zou J
Biological & pharmaceutical bulletin 2017;40(8):1260-1267
Biological & pharmaceutical bulletin 2017;40(8):1260-1267
Intranasal Delivery of a Caspase-1 Inhibitor in the Treatment of Global Cerebral Ischemia.
Zhao N, Zhuo X, Lu Y, Dong Y, Ahmed ME, Tucker D, Scott EL, Zhang Q
Molecular neurobiology 2017 Sep;54(7):4936-4952
Molecular neurobiology 2017 Sep;54(7):4936-4952
The RS504393 Influences the Level of Nociceptive Factors and Enhances Opioid Analgesic Potency in Neuropathic Rats.
Kwiatkowski K, Piotrowska A, Rojewska E, Makuch W, Mika J
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2017 Sep;12(3):402-419
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2017 Sep;12(3):402-419
Licochalcone A Prevents the Loss of Dopaminergic Neurons by Inhibiting Microglial Activation in Lipopolysaccharide (LPS)-Induced Parkinson's Disease Models.
Huang B, Liu J, Ju C, Yang D, Chen G, Xu S, Zeng Y, Yan X, Wang W, Liu D, Fu S
International journal of molecular sciences 2017 Sep 22;18(10)
International journal of molecular sciences 2017 Sep 22;18(10)
Spinal CCL1/CCR8 signaling interplay as a potential therapeutic target - Evidence from a mouse diabetic neuropathy model.
Zychowska M, Rojewska E, Piotrowska A, Kreiner G, Nalepa I, Mika J
International immunopharmacology 2017 Nov;52:261-271
International immunopharmacology 2017 Nov;52:261-271
Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production.
Zhang W, Xiao D, Shan L, Zhao J, Mao Q, Xia H
Biotechnology and bioengineering 2017 Nov;114(11):2539-2549
Biotechnology and bioengineering 2017 Nov;114(11):2539-2549
Silk fibroin-Pellethane® cardiovascular patches: Effect of silk fibroin concentration on vascular remodeling in rat model.
Chantawong P, Tanaka T, Uemura A, Shimada K, Higuchi A, Tajiri H, Sakura K, Murakami T, Nakazawa Y, Tanaka R
Journal of materials science. Materials in medicine 2017 Nov 14;28(12):191
Journal of materials science. Materials in medicine 2017 Nov 14;28(12):191
Suppression of MyD88-dependent signaling alleviates neuropathic pain induced by peripheral nerve injury in the rat.
Liu F, Wang Z, Qiu Y, Wei M, Li C, Xie Y, Shen L, Huang Y, Ma C
Journal of neuroinflammation 2017 Mar 31;14(1):70
Journal of neuroinflammation 2017 Mar 31;14(1):70
Fingolimod (FTY720) attenuates social deficits, learning and memory impairments, neuronal loss and neuroinflammation in the rat model of autism.
Wu H, Wang X, Gao J, Liang S, Hao Y, Sun C, Xia W, Cao Y, Wu L
Life sciences 2017 Mar 15;173:43-54
Life sciences 2017 Mar 15;173:43-54
Antibody incubation at 37°C improves fluorescent immunolabeling in free-floating thick tissue sections.
Xiao X, Feng YP, Du B, Sun HR, Ding YQ, Qi JG
BioTechniques 2017 Mar 1;62(3):115-122
BioTechniques 2017 Mar 1;62(3):115-122
Sarsasapogenin-AA13 ameliorates Aβ-induced cognitive deficits via improving neuroglial capacity on Aβ clearance and antiinflammation.
Huang C, Dong D, Jiao Q, Pan H, Ma L, Wang R
CNS neuroscience & therapeutics 2017 Jun;23(6):498-509
CNS neuroscience & therapeutics 2017 Jun;23(6):498-509
Adenosine production by brain cells.
Jackson EK, Kotermanski SE, Menshikova EV, Dubey RK, Jackson TC, Kochanek PM
Journal of neurochemistry 2017 Jun;141(5):676-693
Journal of neurochemistry 2017 Jun;141(5):676-693
CCR6 (CC Chemokine Receptor 6) Is Essential for the Migration of Detrimental Natural Interleukin-17-Producing γδ T Cells in Stroke.
Arunachalam P, Ludewig P, Melich P, Arumugam TV, Gerloff C, Prinz I, Magnus T, Gelderblom M
Stroke 2017 Jul;48(7):1957-1965
Stroke 2017 Jul;48(7):1957-1965
Low-level laser therapy for beta amyloid toxicity in rat hippocampus.
Lu Y, Wang R, Dong Y, Tucker D, Zhao N, Ahmed ME, Zhu L, Liu TC, Cohen RM, Zhang Q
Neurobiology of aging 2017 Jan;49:165-182
Neurobiology of aging 2017 Jan;49:165-182
Early start of progressive motor deficits in Line 61 α-synuclein transgenic mice.
Rabl R, Breitschaedel C, Flunkert S, Duller S, Amschl D, Neddens J, Niederkofler V, Rockenstein E, Masliah E, Roemer H, Hutter-Paier B
BMC neuroscience 2017 Jan 31;18(1):22
BMC neuroscience 2017 Jan 31;18(1):22
Bexarotene protects against traumatic brain injury in mice partially through apolipoprotein E.
Zhong J, Cheng C, Liu H, Huang Z, Wu Y, Teng Z, He J, Zhang H, Wu J, Cao F, Jiang L, Sun X
Neuroscience 2017 Feb 20;343:434-448
Neuroscience 2017 Feb 20;343:434-448
Vanillin Protects Dopaminergic Neurons against Inflammation-Mediated Cell Death by Inhibiting ERK1/2, P38 and the NF-κB Signaling Pathway.
Yan X, Liu DF, Zhang XY, Liu D, Xu SY, Chen GX, Huang BX, Ren WZ, Wang W, Fu SP, Liu JX
International journal of molecular sciences 2017 Feb 12;18(2)
International journal of molecular sciences 2017 Feb 12;18(2)
Galangin Reduces the Loss of Dopaminergic Neurons in an LPS-Evoked Model of Parkinson's Disease in Rats.
Chen G, Liu J, Jiang L, Ran X, He D, Li Y, Huang B, Wang W, Fu S
International journal of molecular sciences 2017 Dec 21;19(1)
International journal of molecular sciences 2017 Dec 21;19(1)
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
Shah SZA, Zhao D, Taglialatela G, Khan SH, Hussain T, Dong H, Lai M, Zhou X, Yang L
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
Gypenoside Attenuates β Amyloid-Induced Inflammation in N9 Microglial Cells via SOCS1 Signaling.
Cai H, Liang Q, Ge G
Neural plasticity 2016;2016:6362707
Neural plasticity 2016;2016:6362707
Blockade of Toll-Like Receptors (TLR2, TLR4) Attenuates Pain and Potentiates Buprenorphine Analgesia in a Rat Neuropathic Pain Model.
Jurga AM, Rojewska E, Piotrowska A, Makuch W, Pilat D, Przewlocka B, Mika J
Neural plasticity 2016;2016:5238730
Neural plasticity 2016;2016:5238730
Regulation and role of ERK phosphorylation in glial cells following a nigrostriatal pathway injury.
Li D, Tong L, Kawano H, Liu N, Yan HJ, Zhao L, Li HP
Brain research 2016 Oct 1;1648(Pt A):90-100
Brain research 2016 Oct 1;1648(Pt A):90-100
Trans-cinnamaldehyde improves memory impairment by blocking microglial activation through the destabilization of iNOS mRNA in mice challenged with lipopolysaccharide.
Zhang L, Zhang Z, Fu Y, Yang P, Qin Z, Chen Y, Xu Y
Neuropharmacology 2016 Nov;110(Pt A):503-518
Neuropharmacology 2016 Nov;110(Pt A):503-518
Participation of pro- and anti-nociceptive interleukins in botulinum toxin A-induced analgesia in a rat model of neuropathic pain.
Zychowska M, Rojewska E, Makuch W, Luvisetto S, Pavone F, Marinelli S, Przewlocka B, Mika J
European journal of pharmacology 2016 Nov 15;791:377-388
European journal of pharmacology 2016 Nov 15;791:377-388
Methylene Blue promotes cortical neurogenesis and ameliorates behavioral deficit after photothrombotic stroke in rats.
Ahmed ME, Tucker D, Dong Y, Lu Y, Zhao N, Wang R, Zhang Q
Neuroscience 2016 Nov 12;336:39-48
Neuroscience 2016 Nov 12;336:39-48
Impact of acquired and innate immunity on spinal cord ischemia and reperfusion injury.
Yamanaka K, Sasaki N, Fujita Y, Kawamoto A, Hirata K, Okita Y
General thoracic and cardiovascular surgery 2016 May;64(5):251-9
General thoracic and cardiovascular surgery 2016 May;64(5):251-9
Blockade of IL-18 signaling diminished neuropathic pain and enhanced the efficacy of morphine and buprenorphine.
Pilat D, Piotrowska A, Rojewska E, Jurga A, Ślusarczyk J, Makuch W, Basta-Kaim A, Przewlocka B, Mika J
Molecular and cellular neurosciences 2016 Mar;71:114-24
Molecular and cellular neurosciences 2016 Mar;71:114-24
Pharmacological kynurenine 3-monooxygenase enzyme inhibition significantly reduces neuropathic pain in a rat model.
Rojewska E, Piotrowska A, Makuch W, Przewlocka B, Mika J
Neuropharmacology 2016 Mar;102:80-91
Neuropharmacology 2016 Mar;102:80-91
Expression of allograft inflammatory factor-1 in peripheral blood monocytes and synovial membranes in patients with rheumatoid arthritis.
Pawlik A, Kotrych D, Paczkowska E, Roginska D, Dziedziejko V, Safranow K, Machalinski B
Human immunology 2016 Jan;77(1):131-136
Human immunology 2016 Jan;77(1):131-136
Beneficial properties of maraviroc on neuropathic pain development and opioid effectiveness in rats.
Kwiatkowski K, Piotrowska A, Rojewska E, Makuch W, Jurga A, Slusarczyk J, Trojan E, Basta-Kaim A, Mika J
Progress in neuro-psychopharmacology & biological psychiatry 2016 Jan 4;64:68-78
Progress in neuro-psychopharmacology & biological psychiatry 2016 Jan 4;64:68-78
Treatment with a carbon monoxide-releasing molecule (CORM-2) inhibits neuropathic pain and enhances opioid effectiveness in rats.
Jurga AM, Piotrowska A, Starnowska J, Rojewska E, Makuch W, Mika J
Pharmacological reports : PR 2016 Feb;68(1):206-13
Pharmacological reports : PR 2016 Feb;68(1):206-13
Intrathecal Injection of Human Umbilical Cord-Derived Mesenchymal Stem Cells Ameliorates Neuropathic Pain in Rats.
Chen C, Chen F, Yao C, Shu S, Feng J, Hu X, Hai Q, Yao S, Chen X
Neurochemical research 2016 Dec;41(12):3250-3260
Neurochemical research 2016 Dec;41(12):3250-3260
Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy.
Popiolek-Barczyk K, Kolosowska N, Piotrowska A, Makuch W, Rojewska E, Jurga AM, Pilat D, Mika J
Neural plasticity 2015;2015:676473
Neural plasticity 2015;2015:676473
NOD2 is involved in the inflammatory response after cerebral ischemia-reperfusion injury and triggers NADPH oxidase 2-derived reactive oxygen species.
Liu H, Wei X, Kong L, Liu X, Cheng L, Yan S, Zhang X, Chen L
International journal of biological sciences 2015;11(5):525-35
International journal of biological sciences 2015;11(5):525-35
Intervention with exercise restores motor deficits but not nigrostriatal loss in a progressive MPTP mouse model of Parkinson's disease.
Sconce MD, Churchill MJ, Greene RE, Meshul CK
Neuroscience 2015 Jul 23;299:156-74
Neuroscience 2015 Jul 23;299:156-74
Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson's disease models are mediated by GPR109A-dependent mechanisms.
Fu SP, Wang JF, Xue WJ, Liu HM, Liu BR, Zeng YL, Li SN, Huang BX, Lv QK, Wang W, Liu JX
Journal of neuroinflammation 2015 Jan 17;12:9
Journal of neuroinflammation 2015 Jan 17;12:9
The influence of microglia activation on the efficacy of amitriptyline, doxepin, milnacipran, venlafaxine and fluoxetine in a rat model of neuropathic pain.
Zychowska M, Rojewska E, Makuch W, Przewlocka B, Mika J
European journal of pharmacology 2015 Feb 15;749:115-23
European journal of pharmacology 2015 Feb 15;749:115-23
Targeting the CD80/CD86 costimulatory pathway with CTLA4-Ig directs microglia toward a repair phenotype and promotes axonal outgrowth.
Louveau A, Nerrière-Daguin V, Vanhove B, Naveilhan P, Neunlist M, Nicot A, Boudin H
Glia 2015 Dec;63(12):2298-312
Glia 2015 Dec;63(12):2298-312
Chronic Noise Exposure Acts Cumulatively to Exacerbate Alzheimer's Disease-Like Amyloid-β Pathology and Neuroinflammation in the Rat Hippocampus.
Cui B, Li K, Gai Z, She X, Zhang N, Xu C, Chen X, An G, Ma Q, Wang R
Scientific reports 2015 Aug 7;5:12943
Scientific reports 2015 Aug 7;5:12943
Minocycline enhances the effectiveness of nociceptin/orphanin FQ during neuropathic pain.
Popiolek-Barczyk K, Rojewska E, Jurga AM, Makuch W, Zador F, Borsodi A, Piotrowska A, Przewlocka B, Mika J
BioMed research international 2014;2014:762930
BioMed research international 2014;2014:762930
Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy.
Ota K, Obayashi M, Ozaki K, Ichinose S, Kakita A, Tada M, Takahashi H, Ando N, Eishi Y, Mizusawa H, Ishikawa K
Acta neuropathologica communications 2014 Sep 11;2:136
Acta neuropathologica communications 2014 Sep 11;2:136
Photoreceptor degeneration, structural remodeling and glial activation: a morphological study on a genetic mouse model for pericyte deficiency.
Genové G, Mollick T, Johansson K
Neuroscience 2014 Oct 24;279:269-84
Neuroscience 2014 Oct 24;279:269-84
Genetics of gene expression characterizes response to selective breeding for alcohol preference.
Hoffman PL, Saba LM, Flink S, Grahame NJ, Kechris K, Tabakoff B
Genes, brain, and behavior 2014 Nov;13(8):743-57
Genes, brain, and behavior 2014 Nov;13(8):743-57
Cold-inducible RNA-binding protein mediates neuroinflammation in cerebral ischemia.
Zhou M, Yang WL, Ji Y, Qiang X, Wang P
Biochimica et biophysica acta 2014 Jul;1840(7):2253-61
Biochimica et biophysica acta 2014 Jul;1840(7):2253-61
Peripheral immunomodulation with ginsenoside Rg1 ameliorates neuroinflammation-induced behavioral deficits in rats.
Zheng X, Liang Y, Kang A, Ma SJ, Xing L, Zhou YY, Dai C, Xie H, Xie L, Wang GJ, Hao HP
Neuroscience 2014 Jan 3;256:210-22
Neuroscience 2014 Jan 3;256:210-22
Involvement of pro- and antinociceptive factors in minocycline analgesia in rat neuropathic pain model.
Rojewska E, Popiolek-Barczyk K, Jurga AM, Makuch W, Przewlocka B, Mika J
Journal of neuroimmunology 2014 Dec 15;277(1-2):57-66
Journal of neuroimmunology 2014 Dec 15;277(1-2):57-66
Maternal bisphenol a diet induces anxiety-like behavior in female juvenile with neuroimmune activation.
Luo G, Wang S, Li Z, Wei R, Zhang L, Liu H, Wang C, Niu R, Wang J
Toxicological sciences : an official journal of the Society of Toxicology 2014 Aug 1;140(2):364-73
Toxicological sciences : an official journal of the Society of Toxicology 2014 Aug 1;140(2):364-73
Minocycline influences the anti-inflammatory interleukins and enhances the effectiveness of morphine under mice diabetic neuropathy.
Zychowska M, Rojewska E, Kreiner G, Nalepa I, Przewlocka B, Mika J
Journal of neuroimmunology 2013 Sep 15;262(1-2):35-45
Journal of neuroimmunology 2013 Sep 15;262(1-2):35-45
ABT-702, an adenosine kinase inhibitor, attenuates inflammation in diabetic retinopathy.
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse spleen tissue were subjected to SDS PAGE followed by western blot with 10904-1-AP(IBA1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using AIF1 antibody 10904-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-IBA1 (IP:10904-1-AP, 3ug; Detection:10904-1-AP 1:500) with U-937 cells lysate 3000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 10904-1-AP(IBA1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
