Antibody data
- Antibody Data
- Antigen structure
- References [58]
- Comments [0]
- Validations [0]
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- Product number
- 66827-1-Ig - Provider product page

- Provider
- Proteintech Group
- Product name
- IBA1 antibody
- Antibody type
- Monoclonal
- Description
- IBA1 antibody (Cat. #66827-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1C6A10
- Vial size
- 20ul, 150ul
Submitted references EGCG-loaded nanoparticles attenuate post-SAH white matter injury by targeting HO-1/S100A10 to suppress oxidative stress-induced reactive astrocytes.
Gut microbial metabolite indole-3-acetic acid inhibits microglia-mediated synaptic loss in Alzheimer's disease by targeting CCR4.
Intermittent fasting protects MPTP-induced Parkinson's disease mouse model through regulating gut microbiota dysbiosis.
Manipulation therapy alleviates neuropathic pain via the SOCS1 m(6)A epigenetic loop.
An AIM2 inflammasome biomimetic mineralization inhibitor for vascular dementia therapy.
The therapeutic mechanisms of Compound Kushen Injection in relieving cancer-induced bone pain by targeting Nav1.7 and microglial activation.
Icariside II Ameliorates Depression Induced by High-Fat Diet via the Microbiota-Gut-Brain Axis in Mice.
Curcumin Alleviates Microglia-Mediated Neuroinflammation and Neuronal Ferroptosis Following Experimental Subarachnoid Hemorrhage by Modulating the Nrf2/HO-1 Signaling Pathway.
Proteomic Profiling and Therapeutic Targeting of Oxidative Stress in Autoimmune Encephalitis.
Intranasal oxytocin alleviates postsurgical pain and comorbid anxiety in mice: Participation of BK(Ca) channels in the hippocampus.
GPR43 regulates mitochondrial apoptosis through the cyclophilin D pathway in Alzheimer's disease.
Aldosterone promotes calcification of vascular smooth muscle cells in mice through the AIF-1/Wnt/β-catenin signaling pathway.
Calcineurin/NFAT1/Smad2 signaling regulates microglial autophagy that contributes to neuroinflammation and cognitive deficit in mice with sepsis-associated encephalopathy.
Rhein alleviates MPTP-induced Parkinson's disease by suppressing neuroinflammation via MAPK/IκB pathway.
Withaferin A protects against epilepsy by promoting LCN2-mediated astrocyte polarization to stopping neuronal ferroptosis.
Withania somnifera (Ashwagandha) Improves Spatial Memory, Anxiety and Depressive-like Behavior in the 5xFAD Mouse Model of Alzheimer's Disease.
Bleomycin triggers chronic mechanical nociception by activating TRPV1 and glial reaction-mediated neuroinflammation via TSLP/TSLPR/pSTAT5 signals.
Cynarin inhibits microglia-induced pyroptosis and neuroinflammation via Nrf2/ROS/NLRP3 axis after spinal cord injury.
Single-cell RNA-sequencing reveals a unique landscape of the tumor microenvironment in obesity-associated breast cancer.
Whole-body vibration elicits 40 Hz cortical gamma oscillations and ameliorates age-related cognitive impairment through hippocampal astrocyte synapses in male rats.
Targeting of ubiquitination and degradation of KLF15 by E3 ubiquitin ligase KBTBD7 regulates LPS-induced septic brain injury in microglia.
Involvement of microglia-expressed MS4A6A in the onset of glioblastoma.
CDDO regulates central and peripheral sensitization to attenuate post-herpetic neuralgia by targeting TRPV1/PKC-δ/p-Akt signals.
N6022 attenuates cerebral ischemia/reperfusion injury-induced microglia ferroptosis by promoting Nrf2 nuclear translocation and inhibiting the GSNOR/GSTP1 axis.
Roles of mechanosensitive ion channel PIEZO1 in the pathogenesis of brain injury after experimental intracerebral hemorrhage.
Distinct roles of TREM2 in central nervous system cancers and peripheral cancers.
Mitochondrial transplantation confers protection against the effects of ischemic stroke by repressing microglial pyroptosis and promoting neurogenesis.
mRNA and circRNA mislocalization to synapses are key features of Alzheimer's disease.
Local Delivery of Dual Stem Cell-Derived Exosomes Using an Electrospun Nanofibrous Platform for the Treatment of Traumatic Brain Injury.
Single-Cell Transcriptomic Sequencing Reveals Tissue Architecture and Deciphers Pathological Reprogramming During Retinal Ischemia in Macaca fascicularis.
Pathological features and molecular signatures of early olfactory dysfunction in 3xTg-AD model mice.
Safranal acts as a neurorestorative agent in rats with cerebral ischemic stroke via upregulating SIRT1.
TRPM7 contributes to pyroptosis and its involvement in status epilepticus.
Neuron-targeted liposomal coenzyme Q10 attenuates neuronal ferroptosis after subarachnoid hemorrhage by activating the ferroptosis suppressor protein 1/coenzyme Q10 system.
Peroxiredoxin 2 Is a Potential Objective Indicator for Severity and the Clinical Status of Subarachnoid Hemorrhage Patients.
ChemR23 activation attenuates cognitive impairment in chronic cerebral hypoperfusion by inhibiting NLRP3 inflammasome-induced neuronal pyroptosis.
ER stress induced immunopathology involving complement in CADASIL: implications for therapeutics.
Mechanistic Insights into the Role of OPN in Mediating Brain Damage via Triggering Lysosomal Damage in Microglia/Macrophage.
Activation of HCA2 regulates microglial responses to alleviate neurodegeneration in LPS-induced in vivo and in vitro models.
BRG1 alleviates microglial activation by promoting the KEAP1-NRF2/HO-1 signaling pathway and minimizing oxidative damage in cerebral ischemia-reperfusion.
Hydrogen inhalation therapy regulates lactic acid metabolism following subarachnoid hemorrhage through the HIF-1α pathway.
Effects of magnetically targeted iron oxide@polydopamine-labeled human umbilical cord mesenchymal stem cells in cerebral infarction in mice.
CXCR4-BTK axis mediate pyroptosis and lipid peroxidation in early brain injury after subarachnoid hemorrhage via NLRP3 inflammasome and NF-κB pathway.
Hmox1 is Identified as a Ferroptosis Hub Gene and Associated with the M1 Type Microglia/Macrophage Polarization in Spinal Cord Injury: Bioinformatics and Experimental Validation.
Fatal iatrogenic cerebral β-amyloid-related arteritis in a woman treated with lecanemab for Alzheimer's disease.
Calycosin attenuates the inflammatory damage of microglia induced by oxygen and glucose deprivation through the HMGB1/TLR4/NF-κB signaling pathway.
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation.
Differential perivascular microglial activation in the deep white matter in vascular dementia developed post-stroke.
An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation.
Repair of Spinal Cord Injury by Inhibition of PLK4 Expression Through Local Delivery of siRNA-Loaded Nanoparticles.
Malignant Melanoma-Derived Exosomes Induce Endothelial Damage and Glial Activation on a Human BBB Chip Model.
Senkyunolide I Protects against Sepsis-Associated Encephalopathy by Attenuating Sleep Deprivation in a Murine Model of Cecal Ligation and Puncture.
Upregulation of TRPC5 in hippocampal excitatory synapses improves memory impairment associated with neuroinflammation in microglia knockout IL-10 mice.
CCP1, a Tubulin Deglutamylase, Increases Survival of Rodent Spinal Cord Neurons following Glutamate-Induced Excitotoxicity.
Proto-oncogene tyrosine-protein kinase SRC (Src) inhibition in microglia relieves neuroinflammation in neuropathic pain mouse models.
Plasminogen Activator Urokinase Receptor Implies Immunosuppressive Features and Acts as an Unfavorable Prognostic Biomarker in Glioma.
Intravenously Infusing the Secretome of Adipose-Derived Mesenchymal Stem Cells Ameliorates Neuroinflammation and Neurological Functioning After Traumatic Brain Injury.
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International immunopharmacology 2026 Apr 15;175:116447
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Manipulation therapy alleviates neuropathic pain via the SOCS1 m(6)A epigenetic loop.
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An AIM2 inflammasome biomimetic mineralization inhibitor for vascular dementia therapy.
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Curcumin Alleviates Microglia-Mediated Neuroinflammation and Neuronal Ferroptosis Following Experimental Subarachnoid Hemorrhage by Modulating the Nrf2/HO-1 Signaling Pathway.
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Intranasal oxytocin alleviates postsurgical pain and comorbid anxiety in mice: Participation of BK(Ca) channels in the hippocampus.
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Aldosterone promotes calcification of vascular smooth muscle cells in mice through the AIF-1/Wnt/β-catenin signaling pathway.
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Calcineurin/NFAT1/Smad2 signaling regulates microglial autophagy that contributes to neuroinflammation and cognitive deficit in mice with sepsis-associated encephalopathy.
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International immunopharmacology 2023 Jun;119:110201
Hydrogen inhalation therapy regulates lactic acid metabolism following subarachnoid hemorrhage through the HIF-1α pathway.
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Biochemical and biophysical research communications 2023 Jun 30;663:192-201
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Aging 2023 Feb 28;15(4):1130-1142
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Molecular neurobiology 2023 Dec;60(12):7151-7165
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Nature communications 2023 Dec 12;14(1):8220
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Acta biochimica et biophysica Sinica 2023 Aug 1;55(9):1415-1424
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
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International immunopharmacology 2022 Oct;111:109083
International immunopharmacology 2022 Oct;111:109083
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Brain pathology (Zurich, Switzerland) 2022 Nov;32(6):e13101
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Cell & bioscience 2022 Nov 8;12(1):182
Cell & bioscience 2022 Nov 8;12(1):182
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Journal of molecular neuroscience : MN 2022 Mar;72(3):544-554
Malignant Melanoma-Derived Exosomes Induce Endothelial Damage and Glial Activation on a Human BBB Chip Model.
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Biosensors 2022 Jan 31;12(2)
Biosensors 2022 Jan 31;12(2)
Senkyunolide I Protects against Sepsis-Associated Encephalopathy by Attenuating Sleep Deprivation in a Murine Model of Cecal Ligation and Puncture.
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Oxidative medicine and cellular longevity 2021;2021:6647258
Upregulation of TRPC5 in hippocampal excitatory synapses improves memory impairment associated with neuroinflammation in microglia knockout IL-10 mice.
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Journal of neuroinflammation 2021 Nov 26;18(1):275
Journal of neuroinflammation 2021 Nov 26;18(1):275
CCP1, a Tubulin Deglutamylase, Increases Survival of Rodent Spinal Cord Neurons following Glutamate-Induced Excitotoxicity.
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eNeuro 2021 Mar-Apr;8(2)
eNeuro 2021 Mar-Apr;8(2)
Proto-oncogene tyrosine-protein kinase SRC (Src) inhibition in microglia relieves neuroinflammation in neuropathic pain mouse models.
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Bioengineered 2021 Dec;12(2):11390-11398
Plasminogen Activator Urokinase Receptor Implies Immunosuppressive Features and Acts as an Unfavorable Prognostic Biomarker in Glioma.
Zeng F, Li G, Liu X, Zhang K, Huang H, Jiang T, Zhang Y
The oncologist 2021 Aug;26(8):e1460-e1469
The oncologist 2021 Aug;26(8):e1460-e1469
Intravenously Infusing the Secretome of Adipose-Derived Mesenchymal Stem Cells Ameliorates Neuroinflammation and Neurological Functioning After Traumatic Brain Injury.
Xu C, Diao YF, Wang J, Liang J, Xu HH, Zhao ML, Zheng B, Luan Z, Wang JJ, Yang XP, Wei MG, Duan JH, Wang KQ, Chen C, Chen F, Ming D, Zhang S, Sun HT, Li XH
Stem cells and development 2020 Feb 15;29(4):222-234
Stem cells and development 2020 Feb 15;29(4):222-234
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