11-8069-25

antibody from ABEOMICS Inc.
Targeting: ASAP1 CENTB4, DDEF1, KIAA1249, PAP, ZG14P
Provider product page for 11-8069-25

Antibody data

Product number
11-8069-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-ASAP1 Antibody
Antibody type
Polyclonal
Description
ASAP (Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1) or Development and differentiation-enhancing factor 1 or DDEF1 is an ADP-ribosylation factor (ARF) GTPase-activating protein with two known isoforms: ASAP1a and ASAP1b (125 and 126 kDa, respectively). ASAP contains a pleckstrin homology (PH) domain, a zinc finger motif, 3 ankyrin repeats, a proline-rich region containing several SH3 ligand motifs, and an SH3 domain. GTPase-activating property of ASAP1 is induced by phosphatidylinositol 4,5-biphosphate (PIP2) of the PH domain. ASAP1 plays an important role in cytoskeleton remodeling and regulation of membrane trafficking. ASAP1 acts as a proto-oncogene in breast cancer and other malignant tumors. ASAP is highly expressed in brain tissue.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant ASAP1
protein (amino acids 912-1115) was
used as the immunogen for this anti
body.
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
ASAP1 protein structure - 11-8069-25 shown in red.