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- Antigen structure
- References [7]
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- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- H00004218-M02 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00004218-M02, RRID:AB_2175315
- Product name
- Mouse Monoclonal RAB8A Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. RAB8A - RAB8A, member RAS oncogene family
- Reactivity
- Human, Mouse, Zebrafish
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Synaptic-like Vesicles Facilitate Pioneer Axon Invasion.
Basal exon skipping and nonsense-associated altered splicing allows bypassing complete CEP290 loss-of-function in individuals with unusually mild retinal disease.
Integrin α8 and Pcdh15 act as a complex to regulate cilia biogenesis in sensory cells.
Loss-of-function of the ciliopathy protein Cc2d2a disorganizes the vesicle fusion machinery at the periciliary membrane and indirectly affects Rab8-trafficking in zebrafish photoreceptors.
Critical role of Rab11a-mediated recycling endosomes in the assembly of type I parainfluenza viruses.
Synaptotagmin-like protein 4 and Rab8 interact and increase dense granule release in platelets.
Ahi1, whose human ortholog is mutated in Joubert syndrome, is required for Rab8a localization, ciliogenesis and vesicle trafficking.
Nichols EL, Smith CJ
Current biology : CB 2019 Aug 19;29(16):2652-2664.e4
Current biology : CB 2019 Aug 19;29(16):2652-2664.e4
Basal exon skipping and nonsense-associated altered splicing allows bypassing complete CEP290 loss-of-function in individuals with unusually mild retinal disease.
Barny I, Perrault I, Michel C, Soussan M, Goudin N, Rio M, Thomas S, Attié-Bitach T, Hamel C, Dollfus H, Kaplan J, Rozet JM, Gerard X
Human molecular genetics 2018 Aug 1;27(15):2689-2702
Human molecular genetics 2018 Aug 1;27(15):2689-2702
Integrin α8 and Pcdh15 act as a complex to regulate cilia biogenesis in sensory cells.
Goodman L, Zallocchi M
Journal of cell science 2017 Nov 1;130(21):3698-3712
Journal of cell science 2017 Nov 1;130(21):3698-3712
Loss-of-function of the ciliopathy protein Cc2d2a disorganizes the vesicle fusion machinery at the periciliary membrane and indirectly affects Rab8-trafficking in zebrafish photoreceptors.
Ojeda Naharros I, Gesemann M, Mateos JM, Barmettler G, Forbes A, Ziegler U, Neuhauss SCF, Bachmann-Gagescu R
PLoS genetics 2017 Dec;13(12):e1007150
PLoS genetics 2017 Dec;13(12):e1007150
Critical role of Rab11a-mediated recycling endosomes in the assembly of type I parainfluenza viruses.
Stone R, Hayashi T, Bajimaya S, Hodges E, Takimoto T
Virology 2016 Jan;487:11-8
Virology 2016 Jan;487:11-8
Synaptotagmin-like protein 4 and Rab8 interact and increase dense granule release in platelets.
Hampson A, O'Connor A, Smolenski A
Journal of thrombosis and haemostasis : JTH 2013 Jan;11(1):161-8
Journal of thrombosis and haemostasis : JTH 2013 Jan;11(1):161-8
Ahi1, whose human ortholog is mutated in Joubert syndrome, is required for Rab8a localization, ciliogenesis and vesicle trafficking.
Hsiao YC, Tong ZJ, Westfall JE, Ault JG, Page-McCaw PS, Ferland RJ
Human molecular genetics 2009 Oct 15;18(20):3926-41
Human molecular genetics 2009 Oct 15;18(20):3926-41
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: RAB8A Antibody (3G1) [H00004218-M02] - RAB8A monoclonal antibody (M02), clone 3G1 Analysis of RAB8A expression in Hela S3 NE.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunocytochemistry/Immunofluorescence: RAB8A Antibody (3G1) [H00004218-M02] - Neuromast hair cells of zebrafish embryos stained with RAB8A antibody. Donkey anti-mouse Alexa Fluor 594 secondary antibody was used. Image from verified customer.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: RAB8A Antibody (3G1) [H00004218-M02] - Immunoperoxidase of monoclonal antibody to RAB8A on formalin-fixed paraffin-embedded human lymphoma. [antibody concentration 3 ug/ml]
