Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [24]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 55296-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55296-1-AP, RRID:AB_10858398
- Product name
- RAB8A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RAB8A antibody (Cat. #55296-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references SARS-CoV-2 NSP2 as a Potential Delivery Vehicle for Proteins.
The Immune Checkpoint Protein PD-L1 Regulates Ciliogenesis and Hedgehog Signaling.
Klotho-beta attenuates Rab8a-mediated exosome regulation and promotes prostate cancer progression.
Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers.
Mannan-Binding Lectin via Interaction With Cell Surface Calreticulin Promotes Senescence of Activated Hepatic Stellate Cells to Limit Liver Fibrosis Progression.
Pu-erh tea increases the metabolite Cinnabarinic acid to improve circadian rhythm disorder-induced obesity.
Rab8A promotes breast cancer progression by increasing surface expression of Tropomyosin-related kinase B.
The Exocyst Is Required for CD36 Fatty Acid Translocase Trafficking and Free Fatty Acid Uptake in Skeletal Muscle Cells.
Syntaxin 2 promotes colorectal cancer growth by increasing the secretion of exosomes.
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.
Rab35 and glucocorticoids regulate APP and BACE1 trafficking to modulate Aβ production.
S-acylation regulates the trafficking and stability of the unconventional Q-SNARE STX19.
Legionella remodels the plasma membrane-derived vacuole by utilizing exocyst components as tethers.
Acid ceramidase inhibition ameliorates α-synuclein accumulation upon loss of GBA1 function.
The small GTPase RSG1 controls a final step in primary cilia initiation.
Exophagy of annexin A2 via RAB11, RAB8A and RAB27A in IFN-γ-stimulated lung epithelial cells.
The Parkinson's disease-linked protein TMEM230 is required for Rab8a-mediated secretory vesicle trafficking and retromer trafficking.
Rasip1-Mediated Rho GTPase Signaling Regulates Blood Vessel Tubulogenesis via Nonmuscle Myosin II.
The serologically defined colon cancer antigen-3 (SDCCAG3) is involved in the regulation of ciliogenesis.
Chibby promotes ciliary vesicle formation and basal body docking during airway cell differentiation.
Ciliopathy-associated gene Cc2d2a promotes assembly of subdistal appendages on the mother centriole during cilia biogenesis.
RAB8A a new biomarker for endometrial cancer?
ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting.
A molecular network for de novo generation of the apical surface and lumen.
Zheng N, Liu S, Chen J, Xu Y, Cao W, Lin J, Lu G, Zhang G
Molecular pharmaceutics 2024 Mar 4;21(3):1149-1159
Molecular pharmaceutics 2024 Mar 4;21(3):1149-1159
The Immune Checkpoint Protein PD-L1 Regulates Ciliogenesis and Hedgehog Signaling.
Agborbesong E, Li X
Cells 2024 Jun 8;13(12)
Cells 2024 Jun 8;13(12)
Klotho-beta attenuates Rab8a-mediated exosome regulation and promotes prostate cancer progression.
Wu T, Zhang Y, Han Q, Lu X, Cheng Y, Chen J, Sha J, Xia W
Oncogene 2023 Sep;42(38):2801-2815
Oncogene 2023 Sep;42(38):2801-2815
Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers.
Biswas S, Mandal G, Anadon CM, Chaurio RA, Lopez-Bailon LU, Nagy MZ, Mine JA, Hänggi K, Sprenger KB, Innamarato P, Harro CM, Powers JJ, Johnson J, Fang B, Eysha M, Nan X, Li R, Perez BA, Curiel TJ, Yu X, Rodriguez PC, Conejo-Garcia JR
Immunity 2023 Nov 14;56(11):2570-2583.e6
Immunity 2023 Nov 14;56(11):2570-2583.e6
Mannan-Binding Lectin via Interaction With Cell Surface Calreticulin Promotes Senescence of Activated Hepatic Stellate Cells to Limit Liver Fibrosis Progression.
Luo J, Li L, Chang B, Zhu Z, Deng F, Hu M, Yu Y, Lu X, Chen Z, Zuo D, Zhou J
Cellular and molecular gastroenterology and hepatology 2022;14(1):75-99
Cellular and molecular gastroenterology and hepatology 2022;14(1):75-99
Pu-erh tea increases the metabolite Cinnabarinic acid to improve circadian rhythm disorder-induced obesity.
Hu S, Hu C, Luo L, Zhang H, Zhao S, Liu Z, Zeng L
Food chemistry 2022 Nov 15;394:133500
Food chemistry 2022 Nov 15;394:133500
Rab8A promotes breast cancer progression by increasing surface expression of Tropomyosin-related kinase B.
Liu Y, Zhang Z, Gao X, Ma Q, Yu Z, Huang S
Cancer letters 2022 Jun 1;535:215629
Cancer letters 2022 Jun 1;535:215629
The Exocyst Is Required for CD36 Fatty Acid Translocase Trafficking and Free Fatty Acid Uptake in Skeletal Muscle Cells.
Nakamura NK, Tokunaga DS, Ha HY, Polgar N
Cells 2022 Aug 6;11(15)
Cells 2022 Aug 6;11(15)
Syntaxin 2 promotes colorectal cancer growth by increasing the secretion of exosomes.
Wang Y, Li Y, Zhou H, Qian X, Hu Y
Journal of Cancer 2021;12(7):2050-2058
Journal of Cancer 2021;12(7):2050-2058
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.
Liu M, Zhang W, Li M, Feng J, Kuang W, Chen X, Yang F, Sun Q, Xu Z, Hua J, Yang C, Liu W, Shu Q, Yang Y, Zhou T, Xie S
Cell research 2021 Nov;31(11):1199-1211
Cell research 2021 Nov;31(11):1199-1211
Rab35 and glucocorticoids regulate APP and BACE1 trafficking to modulate Aβ production.
Zhuravleva V, Vaz-Silva J, Zhu M, Gomes P, Silva JM, Sousa N, Sotiropoulos I, Waites CL
Cell death & disease 2021 Dec 8;12(12):1137
Cell death & disease 2021 Dec 8;12(12):1137
S-acylation regulates the trafficking and stability of the unconventional Q-SNARE STX19.
Ampah KK, Greaves J, Shun-Shion AS, Asnawi AW, Lidster JA, Chamberlain LH, Collins MO, Peden AA
Journal of cell science 2018 Oct 22;131(20)
Journal of cell science 2018 Oct 22;131(20)
Legionella remodels the plasma membrane-derived vacuole by utilizing exocyst components as tethers.
Arasaki K, Kimura H, Tagaya M, Roy CR
The Journal of cell biology 2018 Nov 5;217(11):3863-3872
The Journal of cell biology 2018 Nov 5;217(11):3863-3872
Acid ceramidase inhibition ameliorates α-synuclein accumulation upon loss of GBA1 function.
Kim MJ, Jeon S, Burbulla LF, Krainc D
Human molecular genetics 2018 Jun 1;27(11):1972-1988
Human molecular genetics 2018 Jun 1;27(11):1972-1988
The small GTPase RSG1 controls a final step in primary cilia initiation.
Agbu SO, Liang Y, Liu A, Anderson KV
The Journal of cell biology 2018 Jan 2;217(1):413-427
The Journal of cell biology 2018 Jan 2;217(1):413-427
Exophagy of annexin A2 via RAB11, RAB8A and RAB27A in IFN-γ-stimulated lung epithelial cells.
Chen YD, Fang YT, Cheng YL, Lin CF, Hsu LJ, Wang SY, Anderson R, Chang CP, Lin YS
Scientific reports 2017 Jul 18;7(1):5676
Scientific reports 2017 Jul 18;7(1):5676
The Parkinson's disease-linked protein TMEM230 is required for Rab8a-mediated secretory vesicle trafficking and retromer trafficking.
Kim MJ, Deng HX, Wong YC, Siddique T, Krainc D
Human molecular genetics 2017 Feb 15;26(4):729-741
Human molecular genetics 2017 Feb 15;26(4):729-741
Rasip1-Mediated Rho GTPase Signaling Regulates Blood Vessel Tubulogenesis via Nonmuscle Myosin II.
Barry DM, Koo Y, Norden PR, Wylie LA, Xu K, Wichaidit C, Azizoglu DB, Zheng Y, Cobb MH, Davis GE, Cleaver O
Circulation research 2016 Sep 16;119(7):810-26
Circulation research 2016 Sep 16;119(7):810-26
The serologically defined colon cancer antigen-3 (SDCCAG3) is involved in the regulation of ciliogenesis.
Yu F, Sharma S, Skowronek A, Erdmann KS
Scientific reports 2016 Oct 21;6:35399
Scientific reports 2016 Oct 21;6:35399
Chibby promotes ciliary vesicle formation and basal body docking during airway cell differentiation.
Burke MC, Li FQ, Cyge B, Arashiro T, Brechbuhl HM, Chen X, Siller SS, Weiss MA, O'Connell CB, Love D, Westlake CJ, Reynolds SD, Kuriyama R, Takemaru K
The Journal of cell biology 2014 Oct 13;207(1):123-37
The Journal of cell biology 2014 Oct 13;207(1):123-37
Ciliopathy-associated gene Cc2d2a promotes assembly of subdistal appendages on the mother centriole during cilia biogenesis.
Veleri S, Manjunath SH, Fariss RN, May-Simera H, Brooks M, Foskett TA, Gao C, Longo TA, Liu P, Nagashima K, Rachel RA, Li T, Dong L, Swaroop A
Nature communications 2014 Jun 20;5:4207
Nature communications 2014 Jun 20;5:4207
RAB8A a new biomarker for endometrial cancer?
Bie Y, Zhang Z
World journal of surgical oncology 2014 Dec 4;12:371
World journal of surgical oncology 2014 Dec 4;12:371
ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting.
Humbert MC, Weihbrecht K, Searby CC, Li Y, Pope RM, Sheffield VC, Seo S
Proceedings of the National Academy of Sciences of the United States of America 2012 Nov 27;109(48):19691-6
Proceedings of the National Academy of Sciences of the United States of America 2012 Nov 27;109(48):19691-6
A molecular network for de novo generation of the apical surface and lumen.
Bryant DM, Datta A, Rodríguez-Fraticelli AE, Peränen J, Martín-Belmonte F, Mostov KE
Nature cell biology 2010 Nov;12(11):1035-45
Nature cell biology 2010 Nov;12(11):1035-45
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 55296-1-AP(RAB8A antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-RAB8A (IP:55296-1-AP, 3ug; Detection:55296-1-AP 1:500) with HeLa cells lysate 2500ug.
- Sample type
- cell line
