10982-1-AP

antibody from Proteintech Group

Targeting: OSMR OSMRB, OSMRbeta

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

10982-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#10982-1-AP, RRID:AB_2156583

Product name

OSMR antibody

Antibody type

Polyclonal

Description

KD/KO validated OSMR antibody (Cat. #10982-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, monkey and has been validated for the following applications: WB, ELISA.

Reactivity

Human, Simian

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

An Integrated Machine Learning Framework for Developing and Validating a Diagnostic Model of Hub Genes Related to Lipid Metabolism in Chronic Rhinosinusitis.

Xiong P, Liu L, Pi J, Wang J, Lu T, Ke X, Jiang Y, Shen Y, Yang Y
Journal of inflammation research 2025;18:10081-10098

---

Th2 mRNA gene expression analysis separates Prurigo nodularis into two immune signature groups.

Ständer S, Guttman-Yassky E, Yosipovitch G, Wiegmann H, Metze D, Kim M, Del Duca E, Bondensgaard K, Paolini JF, LOTUS‐PN Investigators Group
Journal of the European Academy of Dermatology and Venereology : JEADV 2025 Oct;39(10):1750-1759

---

Multi-omics identifies OSM-OSMR as a key receptor-ligand in the tumor environment of endometrial adenocarcinoma.

Zhou Q, Wu Z, Gu J, Tang X, Li N, Yu M, Lin C
International immunopharmacology 2025 Jul 28;160:114933

---

Multi-omics integrated analysis to generate transcriptome and protome profiles of resveratrol improving Paraquat-induced acute lung injury.

Xu Z, Huang L, Yu Z, Gao Y, Wang R, Du B, Cui X, Yuan J
Ecotoxicology and environmental safety 2025 Jul 15;300:118459

---

A Risk Model Based on Ferroptosis-Related Genes OSMR, G0S2, IGFBP6, IGHG2, and FMOD Predicts Prognosis in Glioblastoma Multiforme.

Wu Y, Liu L, Li Z, Zhang T, Wang Q, Cheng M
CNS neuroscience & therapeutics 2025 Jan;31(1):e70161

---

Integrative multi-omics analysis proposes a metabolic classification of gliomas: distinct metabolic states, immune infiltration, and prognosis.

Zhu Q, Niu W, Mu M, Ye C, Niu C
Journal of translational medicine 2025 Dec 30;24(1):122

---

PCOS endometrium-derived epithelial organoids as a novel model to study endometrial dysfunction.

Luyckx L, Wei M, Saarela U, Myllykangas M, Kinnunen J, Arffman R, Lie Fong S, Vriens J, Vankelecom H, Piltonen TT
Human reproduction (Oxford, England) 2025 Aug 1;40(8):1535-1549

---

Toll-Like receptor 3-mediated interferon-β production is suppressed by oncostatin m and a broader epithelial-mesenchymal transition program.

Chernosky NM, Tamagno I, Polak KL, Chan ER, Yuan X, Jackson MW
Breast cancer research : BCR 2024 Nov 26;26(1):167

---

Neutrophils in nasal polyps exhibit transcriptional adaptation and proinflammatory roles that depend on local polyp milieu.

Zhang C, Zhang Q, Chen J, Li H, Cheng F, Wang Y, Gao Y, Zhou Y, Shi L, Yang Y, Liu J, Xue K, Zhang Y, Yu H, Wang D, Hu L, Wang H, Sun X
JCI insight 2024 Nov 22;9(22)

---

OSMR is a potential driver of inflammation in amyotrophic lateral sclerosis.

Chen W, Jiang S, Li S, Li C, Xu R
Neural regeneration research 2024 Nov 1;19(11):2513-2521

---

Methotrexate for refractory adult atopic dermatitis leads to alterations in cutaneous IL-31 and IL-31RA expression.

Samorano LP, Manfrere KCG, Pereira NV, Takaoka R, Valente NYS, Sotto MN, Silva LFF, Sato MN, Aoki V
Anais brasileiros de dermatologia 2024 Jan-Feb;99(1):72-79

---

Deep spatial proteomics reveals region-specific features of severe COVID-19-related pulmonary injury.

Mao Y, Chen Y, Li Y, Ma L, Wang X, Wang Q, He A, Liu X, Dong T, Gao W, Xu Y, Liu L, Ren L, Liu Q, Zhou P, Hu B, Zhou Y, Tian R, Shi ZL
Cell reports 2024 Feb 27;43(2):113689

---

Oncostatin M-Enriched Small Extracellular Vesicles Derived from Mesenchymal Stem Cells Prevent Isoproterenol-Induced Fibrosis and Enhance Angiogenesis.

Tejedor S, Buigues M, González-King H, Silva AM, García NA, Dekker N, Sepúlveda P
International journal of molecular sciences 2023 Mar 30;24(7)

---

Oncostatin M receptor regulates osteoblast differentiation via extracellular signal-regulated kinase/autophagy signaling.

Zhou J, Yang J, Dong Y, Shi Y, Zhu E, Yuan H, Li X, Wang B
Stem cell research & therapy 2022 Jun 28;13(1):278

---

Oncostatin M Receptor-Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth.

Geethadevi A, Nair A, Parashar D, Ku Z, Xiong W, Deng H, Li Y, George J, McAllister DM, Sun Y, Kadamberi IP, Gupta P, Dwinell MB, Bradley WH, Rader JS, Rui H, Schwabe RF, Zhang N, Pradeep S, An Z, Chaluvally-Raghavan P
Cancer research 2021 Oct 15;81(20):5336-5352

---

Repression of Osmr and Fgfr1 by miR-1/133a prevents cardiomyocyte dedifferentiation and cell cycle entry in the adult heart.

Valussi M, Besser J, Wystub-Lis K, Zukunft S, Richter M, Kubin T, Boettger T, Braun T
Science advances 2021 Oct 15;7(42):eabi6648

---

Elevated lymphocyte specific protein 1 expression is involved in the regulation of leukocyte migration and immunosuppressive microenvironment in glioblastoma.

Cao JY, Guo Q, Guan GF, Zhu C, Zou CY, Zhang LY, Cheng W, Wang GL, Cheng P, Wu AH, Li GY
Aging 2020 Jan 29;12(2):1656-1684

---

Overexpression of oncostatin M receptor regulates local immune response in glioblastoma.

Guo Q, Guan GF, Cao JY, Zou CY, Zhu C, Cheng W, Xu XY, Lin ZG, Cheng P, Wu AH
Journal of cellular physiology 2019 Sep;234(9):15496-15509

---

CD11b(+) cells markedly express the itch cytokine interleukin-31 in polymorphic light eruption.

Patra V, Strobl J, Gruber-Wackernagel A, Vieyra-Garcia P, Stary G, Wolf P
The British journal of dermatology 2019 Nov;181(5):1079-1081

---

IL-31 expression by inflammatory cells is preferentially elevated in atopic dermatitis.

Nobbe S, Dziunycz P, Mühleisen B, Bilsborough J, Dillon SR, French LE, Hofbauer GF
Acta dermato-venereologica 2012 Jan;92(1):24-8

---

Oncostatin M is a major mediator of cardiomyocyte dedifferentiation and remodeling.

Kubin T, Pöling J, Kostin S, Gajawada P, Hein S, Rees W, Wietelmann A, Tanaka M, Lörchner H, Schimanski S, Szibor M, Warnecke H, Braun T
Cell stem cell 2011 Nov 4;9(5):420-32