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- References [13]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 17767-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17767-1-AP, RRID:AB_2213383
- Product name
- USP38 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated USP38 antibody (Cat. #17767-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references METTL7B-induced histone lactylation prevents heart failure by ameliorating cardiac remodelling.
A cross-tissue transcriptome-wide association study identifies new key genes in ischemic stroke.
The deubiquitinase USP24 suppresses ferroptosis in triple-negative breast cancer by stabilizing DHODH protein.
USP38 exacerbates myocardial injury and malignant ventricular arrhythmias after ischemia/reperfusion by promoting ferroptosis through the P53/SLC7A11 pathway.
Inhibition of Lactate Accumulation via USP38-Mediated MCT1 Deubiquitination Activates AKT/mTOR Signaling to Mitigate PM2.5-Induced Lung Injury.
Methylprednisolone alleviates lung injury in sepsis by regulating miR-151-5p/USP38 pathway.
ADAR promotes USP38 auto-deubiquitylation and stabilization in an RNA editing-independent manner in esophageal squamous cell carcinoma.
USP38 exacerbates pressure overload-induced left ventricular electrical remodeling.
USP38 promotes deubiquitination of K11-linked polyubiquitination of HIF1α at Lys769 to enhance hypoxia signaling.
Ubiquitin specific peptidase 38 promotes the progression of gastric cancer through upregulation of fatty acid synthase.
The deubiquitinase USP38 promotes cell proliferation through stabilizing c-Myc.
USP38 regulates the stemness and chemoresistance of human colorectal cancer via regulation of HDAC3.
USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein.
Chen Z, Zhong M, Lin Y, Zhang W, Zhu Y, Chen L, Huang Z, Luo K, Lu Z, Huang Z, Yan Y
Journal of molecular and cellular cardiology 2025 May;202:64-80
Journal of molecular and cellular cardiology 2025 May;202:64-80
A cross-tissue transcriptome-wide association study identifies new key genes in ischemic stroke.
Song Z, Han Y, Li W, Xu Y, He Y, Wang Y
Gene 2025 Mar 15;941:149207
Gene 2025 Mar 15;941:149207
The deubiquitinase USP24 suppresses ferroptosis in triple-negative breast cancer by stabilizing DHODH protein.
Yang L, An X, Yang S, Lin X, Chen Z, Xue Q, Chen X, Wang Y, Yan D, Chen S, Fan Y, Tang D, Yu W, Liu J, Chen X
Cell death & disease 2025 Jul 26;16(1):564
Cell death & disease 2025 Jul 26;16(1):564
USP38 exacerbates myocardial injury and malignant ventricular arrhythmias after ischemia/reperfusion by promoting ferroptosis through the P53/SLC7A11 pathway.
Gong Y, Yang H, Chen T, Zhang J, Kong B, Shuai W, Huang H
International immunopharmacology 2025 Jan 3;145:113727
International immunopharmacology 2025 Jan 3;145:113727
Inhibition of Lactate Accumulation via USP38-Mediated MCT1 Deubiquitination Activates AKT/mTOR Signaling to Mitigate PM2.5-Induced Lung Injury.
Chen Z, Cao J, Hou S, Chao L, Li J, Jia Z, Han S, Chen J, Yan X
Journal of clinical laboratory analysis 2025 Apr;39(8):e70028
Journal of clinical laboratory analysis 2025 Apr;39(8):e70028
Methylprednisolone alleviates lung injury in sepsis by regulating miR-151-5p/USP38 pathway.
Yuan Z, Wang Q, Tan Y, Wei S, Shen J, Zhuang L, Yang Q, Xu Y, Luo Y
International immunopharmacology 2024 Sep 10;138:112548
International immunopharmacology 2024 Sep 10;138:112548
ADAR promotes USP38 auto-deubiquitylation and stabilization in an RNA editing-independent manner in esophageal squamous cell carcinoma.
Hu Q, Chen Y, Zhou Q, Deng S, Hou W, Yi Y, Li C, Tang J
The Journal of biological chemistry 2024 Oct;300(10):107789
The Journal of biological chemistry 2024 Oct;300(10):107789
USP38 exacerbates pressure overload-induced left ventricular electrical remodeling.
Pan Y, Xiao Z, Yang H, Kong B, Meng H, Shuai W, Huang H
Molecular medicine (Cambridge, Mass.) 2024 Jun 27;30(1):97
Molecular medicine (Cambridge, Mass.) 2024 Jun 27;30(1):97
USP38 promotes deubiquitination of K11-linked polyubiquitination of HIF1α at Lys769 to enhance hypoxia signaling.
Wang R, Cai X, Li X, Li J, Liu X, Wang J, Xiao W
The Journal of biological chemistry 2024 Jan;300(1):105532
The Journal of biological chemistry 2024 Jan;300(1):105532
Ubiquitin specific peptidase 38 promotes the progression of gastric cancer through upregulation of fatty acid synthase.
Zheng Z, Shang Y, Xu R, Yan X, Wang X, Cai J, Bai Z, Liu X, Yin J, Zhang J, Zhang Z
American journal of cancer research 2022;12(6):2686-2696
American journal of cancer research 2022;12(6):2686-2696
The deubiquitinase USP38 promotes cell proliferation through stabilizing c-Myc.
Xu Z, Hu H, Fang D, Wang J, Zhao K
The international journal of biochemistry & cell biology 2021 Aug;137:106023
The international journal of biochemistry & cell biology 2021 Aug;137:106023
USP38 regulates the stemness and chemoresistance of human colorectal cancer via regulation of HDAC3.
Zhan W, Liao X, Liu J, Tian T, Yu L, Li R
Oncogenesis 2020 May 13;9(5):48
Oncogenesis 2020 May 13;9(5):48
USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein.
Chen S, Yun F, Yao Y, Cao M, Zhang Y, Wang J, Song X, Qian Y
The Journal of experimental medicine 2018 Nov 5;215(11):2850-2867
The Journal of experimental medicine 2018 Nov 5;215(11):2850-2867
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 17767-1-AP(USP38 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 17767-1-AP(USP38 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The USP38 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human USP38. This antibody recognizes human, mouse, rat antigen. The USP38 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
