26417-1-AP

antibody from Proteintech Group

Targeting: BAG6 BAT3, D6S52E, G3, Scythe

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

26417-1-AP

Provider

Proteintech Group

Product name

BAG6 antibody

Antibody type

Polyclonal

Description

KD/KO validated BAG6 antibody (Cat. #26417-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Mechanism underlying CDC20 affecting epithelial ovarian cancer biological behavior by regulating BAG6 ubiquitination.

Zhang X, Bi F, Yang Q
Cellular signalling 2025 Mar;127:111577

---

RAB3A-mediated BAG6 translocation promotes non-small cell lung cancer tumorigenesis and progression.

Liu X, Wang W, Cao W, Li Z, Huang H, Liu F, Wang Y, Zhong Z, Zhang H, Pei X, Chen H
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):2001-2015

---

UBXN1 maintains ER proteostasis and represses UPR activation by modulating translation.

Ahlstedt BA, Ganji R, Mukkavalli S, Paulo JA, Gygi SP, Raman M
EMBO reports 2024 Feb;25(2):672-703

---

Chromosomal 3q amplicon encodes essential regulators of secretory vesicles that drive secretory addiction in cancer.

Tan X, Wang S, Xiao GY, Wu C, Liu X, Zhou B, Jiang Y, Duose DY, Xi Y, Wang J, Gupta K, Pataer A, Roth JA, Kim MP, Chen F, Creighton CJ, Russell WK, Kurie JM
The Journal of clinical investigation 2024 Apr 25;134(12)

---

Deubiquitinase USP19 modulates apoptotic calcium release and endoplasmic reticulum stress by deubiquitinating BAG6 in triple negative breast cancer.

Zhang X, Chen X, Qian F, Zhu Y, He G, Yang J, Wu X, Zhang H, Yu X, Liu X
Clinical and translational medicine 2023 Sep;13(9):e1398

---

The chromatin remodeling protein BRG1 regulates HSC-myofibroblast differentiation and liver fibrosis.

Zhu Y, Kang A, Kuai Y, Guo Y, Miao X, Zhu L, Kong M, Li N
Cell death & disease 2023 Dec 14;14(12):826

---

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

Jülg J, Edbauer D, Behrends C
EMBO reports 2023 Aug 3;24(8):e55895

---

BAG6 negatively regulates the RLR signaling pathway by targeting VISA/MAVS.

Huang JP, Li J, Xiao YP, Xu LG
Frontiers in immunology 2022;13:972184

---

Retinitis pigmentosa 2 pathogenic mutants degrade through BAG6/HUWE1 complex.

Zhang J, Gao H, Jiang N, Jing M, Sun Z, Du C, Zhang J, Wang M, Li J, Gao F, Hu Y, Mu H, Cui X
Experimental eye research 2022 Jul;220:109110

---

BAG6 promotes PINK1 signaling pathway and is essential for mitophagy.

Ragimbeau R, El Kebriti L, Sebti S, Fourgous E, Boulahtouf A, Arena G, Espert L, Turtoi A, Gongora C, Houédé N, Pattingre S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21361

---

The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex.

Ganji R, Mukkavalli S, Somanji F, Raman M
Molecular and cellular biology 2018 Jul 1;38(13)