329604

antibody from BioLegend

Targeting: PDCD1LG2 B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2

Flow cytometry (Recommended by provider)

Antibody Data

Product number

329604

Provider

BioLegend

Proper citation

BioLegend Cat#329604, RRID:AB_1089016

Product name

Biotin anti-human CD273 (B7-DC, PD-L2)

Antibody type

Monoclonal

Antigen

Human PD-L2 cDNA

Description

CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.

Reactivity

Human

Host

Mouse

Conjugate

Biotin

Isotype

IgG

Vial size

100 µg

Concentration

0.5 mg/ml

Storage

The antibody solution should be stored undiluted at 4°C. Do not freeze.