345508

antibody from BioLegend
Targeting: PDCD1LG2 B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2
Provider product page for 345508

Antibody data

Product number
345508 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#345508, RRID:AB_2162176
Product name
APC anti-human CD273 (B7-DC, PD-L2)
Antibody type
Monoclonal
Antigen
Human B7-DC transfected cells
Description
CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions. Clone MIH18 is reported to block PDL2.
Reactivity
Human
Host
Mouse
Conjugate
Red dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
PDCD1LG2 protein structure - 345508 shown in red.