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- Antibody Data
- Antigen structure
- References [4]
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- Product number
- AF2826 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal TIM-4 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects mouse TIM-4 in direct ELISAs and Western blots. In direct ELISAs, less than 2% cross-reactivity with recombinant human (rh) TIM-1, recombinant mouse (rm) TIM-2, rmTIM-3, rhTIM-4, rmTIM-5, and rmTIM-6 is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references IL-4/IL-13 polarization of macrophages enhances Ebola virus glycoprotein-dependent infection.
Mouse macrophages show different requirements for phosphatidylserine receptor Tim4 in efferocytosis.
T cell Ig domain and mucin domain 1 engagement on invariant NKT cells in the presence of TCR stimulation enhances IL-4 production but inhibits IFN-gamma production.
TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells.
Rogers KJ, Brunton B, Mallinger L, Bohan D, Sevcik KM, Chen J, Ruggio N, Maury W
PLoS neglected tropical diseases 2019 Dec;13(12):e0007819
PLoS neglected tropical diseases 2019 Dec;13(12):e0007819
Mouse macrophages show different requirements for phosphatidylserine receptor Tim4 in efferocytosis.
Yanagihashi Y, Segawa K, Maeda R, Nabeshima YI, Nagata S
Proceedings of the National Academy of Sciences of the United States of America 2017 Aug 15;114(33):8800-8805
Proceedings of the National Academy of Sciences of the United States of America 2017 Aug 15;114(33):8800-8805
T cell Ig domain and mucin domain 1 engagement on invariant NKT cells in the presence of TCR stimulation enhances IL-4 production but inhibits IFN-gamma production.
Kim HS, Kim HS, Lee CW, Chung DH
Journal of immunology (Baltimore, Md. : 1950) 2010 Apr 15;184(8):4095-106
Journal of immunology (Baltimore, Md. : 1950) 2010 Apr 15;184(8):4095-106
TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells.
Nakae S, Iikura M, Suto H, Akiba H, Umetsu DT, Dekruyff RH, Saito H, Galli SJ
Blood 2007 Oct 1;110(7):2565-8
Blood 2007 Oct 1;110(7):2565-8
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