12008-1-AP

antibody from Proteintech Group

Targeting: TIMD4 TIM4

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

12008-1-AP

Provider

Proteintech Group

Product name

TIMD4 antibody

Antibody type

Polyclonal

Description

TIMD4 antibody (Cat. #12008-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Analysis of Tim-4 expression in ulcerative colitis and its association with inflammation-related immune infiltration.

Liu Y, Wang Y, Wang X, Zhu L, Zhao C, Zhu J, Wang X
Immunology letters 2026 Mar 29;280:107173

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Multi-omic and functional analyses identified an endoplasmic reticulum stress-driven TIMD4⁺ IL1β⁺ macrophage subpopulation contributes to osteoarthritis progression.

Hao R, Liu C, Li Z, Yu F, Zhao Z, Zhu H, Liu B
Pathology, research and practice 2026 Jun;282:156442

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C-C motif receptor 2 is a core profibrotic factor in uremic cardiomyopathy.

Bao JF, Guo BC, Mo JJ, Zhu H, Jia N, Hou F, Liu Y, Li A
Disease models & mechanisms 2026 Jan 1;19(1)

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Macrophage Tim-4 protects against deep vein thrombosis by binding CK2β to suppress inflammatory responses.

Wang X, Zhang Z, Zheng W, Zhang B, Chu C, Chen J, Liu C, Xu K, Yu Z, Guo Q, Zhao S, Chen X, Bai F, Wang B, Li X, Liu W
Frontiers in immunology 2025;16:1634230

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Cellular Landscape of Synovial Chondromatosis Synovium Revealed by Single-Cell RNA Sequencing.

Zhao H, Jiang F, Zhang P, Bi Y, Shen Y, Ma J, Gong J, Han K, Zhang L, Yu T, Xiao X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70799

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Human leukocyte antigen DR alpha inhibits renal cell carcinoma progression by promoting the polarization of M2 macrophages to M1 via the NF-κB pathway.

Xiong F, Wang B, Zhang H, Zhang G, Liu Y, Liu Y, Wang C
International immunopharmacology 2025 Jan 10;144:113706

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Platelets promote CRC by activating the C5a/C5aR1 axis via PSGL-1/JNK/STAT1 signaling in tumor-associated macrophages.

Li X, Chen X, Gong S, Zhao J, Yao C, Zhu H, Xiao R, Qin Y, Li R, Sun N, Li X, Dong F, Zhao T, Pan Y, Yang J
Theranostics 2023;13(6):2040-2056

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Bone Marrow Mesenchymal Stem Cell-Derived Dermcidin-Containing Migrasomes enhance LC3-Associated Phagocytosis of Pulmonary Macrophages and Protect against Post-Stroke Pneumonia.

Li T, Su X, Lu P, Kang X, Hu M, Li C, Wang S, Lu D, Shen S, Huang H, Liu Y, Deng X, Cai W, Wei L, Lu Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(22):e2206432

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Regulation of the macrophage-hepatic stellate cell interaction by targeting macrophage peroxisome proliferator-activated receptor gamma to prevent non-alcoholic steatohepatitis progression in mice.

Ni XX, Ji PX, Chen YX, Li XY, Sheng L, Lian M, Guo CJ, Hua J
Liver international : official journal of the International Association for the Study of the Liver 2022 Dec;42(12):2696-2712

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Single-Cell RNA-seq Reveals Characteristics of Malignant Cells and Immune Microenvironment in Subcutaneous Panniculitis-Like T-Cell Lymphoma.

Li Z, Wang H, Dong R, Man J, Sun L, Qian X, Zhu X, Cao P, Yu Y, Le J, Fu Y, Wang P, Jiang W, Shen C, Ma Y, Chen L, Xu Y, Shi J, Zhang H, Qian M, Zhai X
Frontiers in oncology 2021;11:611580

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Comparative Proteomic Analysis of tPVAT during Ang II Infusion.

Liang X, Guan H, Sun J, Qi Y, Yao W
Biomedicines 2021 Dec 2;9(12)