H2AZ2

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. Several transcript variants encoding different isoforms, have been identified for this gene. [provided by RefSeq, Oct 2015]

Description

H2A.Z variant histone 2

Tissue specificity

Low tissue specificity

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

7 (44826791 - 44848087)

Ensembl ID

ENSG00000105968  (ver. 103.38)

Orthologs

Mouse H2az2: ENSMUSG00000041126

UniProt

Q71UI9

neXtProt

NX_Q71UI9

Human splice variants
Mouse splice variants

Protein structure