HPA028417

antibody from Atlas Antibodies

Targeting: PHF20L1 CGI-72, FLJ13649, FLJ21615, MGC64923, TDRD20B

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA028417

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA028417, RRID:AB_10602278

Product name

Anti-PHF20L1

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human PHF20L1, Gene description: PHD finger protein 20-like 1, Alternative Gene Names: CGI-72, FLJ13649, FLJ21615, MGC64923, TDRD20B, Validated applications: ICC, IHC, Uniprot ID: A8MW92, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.3 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Methyl-lysine readers PHF20 and PHF20L1 define two distinct gene expression–regulating NSL complexes

Van H, Harkins P, Patel A, Jain A, Lu Y, Bedford M, Santos M
Journal of Biological Chemistry 2022;298(3):101588

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PHD finger protein 20-like protein 1 (PHF20L1) in ovarian cancer: from its overexpression in tissue to its upregulation by the ascites microenvironment

Alberto-Aguilar D, Hernández-Ramírez V, Osorio-Trujillo J, Gallardo-Rincón D, Toledo-Leyva A, Talamás-Rohana P
Cancer Cell International 2022;22(1)

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PHF20L1 as a H3K27me2 reader coordinates with transcriptional repressors to promote breast tumorigenesis

Hou Y, Liu W, Yi X, Yang Y, Su D, Huang W, Yu H, Teng X, Yang Y, Feng W, Zhang T, Gao J, Zhang K, Qiu R, Wang Y
Science Advances 2020;6(16)

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Proteolysis of methylated SOX2 protein is regulated by L3MBTL3 and CRL4DCAF5 ubiquitin ligase

Zhang C, Leng F, Saxena L, Hoang N, Yu J, Alejo S, Lee L, Qi D, Lu F, Sun H, Zhang H
Journal of Biological Chemistry 2019;294(2):476-489

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Ascites from Ovarian Cancer Induces Novel Fucosylated Proteins

Alberto-Aguilar D, Hernández-Ramírez V, Osorio-Trujillo J, Gallardo-Rincón D, Toledo-Leyva A, Talamás-Rohana P
Cancer Microenvironment 2019;12(2-3):181-195

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Methylated DNMT1 and E2F1 are targeted for proteolysis by L3MBTL3 and CRL4DCAF5 ubiquitin ligase

Leng F, Yu J, Zhang C, Alejo S, Hoang N, Sun H, Lu F, Zhang H
Nature Communications 2018;9(1)

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LSD1 demethylase and the methyl-binding protein PHF20L1 prevent SET7 methyltransferase–dependent proteolysis of the stem-cell protein SOX2

Zhang C, Hoang N, Leng F, Saxena L, Lee L, Alejo S, Qi D, Khal A, Sun H, Lu F, Zhang H
Journal of Biological Chemistry 2018;293(10):3663-3674

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Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein

Carr S, Munro S, Sagum C, Fedorov O, Bedford M, La Thangue N
Cell Death & Differentiation 2017;24(12):2139-2149

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An integrated genomic analysis of Tudor domain–containing proteins identifies PHD finger protein 20‐like 1 (PHF20L1) as a candidate oncogene in breast cancer

Jiang Y, Liu L, Shan W, Yang Z
Molecular Oncology 2015;10(2):292-302

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Methyllysine Reader Plant Homeodomain (PHD) Finger Protein 20-like 1 (PHF20L1) Antagonizes DNA (Cytosine-5) Methyltransferase 1 (DNMT1) Proteasomal Degradation

Estève P, Terragni J, Deepti K, Chin H, Dai N, Espejo A, Corrêa I, Bedford M, Pradhan S
Journal of Biological Chemistry 2014;289(12):8277-8287