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- References [7]
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- Western blot [2]
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- Product number
- H00029968-A01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00029968-A01, RRID:AB_547380
- Product name
- Mouse Polyclonal PSAT1 Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified. PSAT1 - phosphoserine aminotransferase 1
- Reactivity
- Human, Bacteria
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation.
Glutamine-utilizing transaminases are a metabolic vulnerability of TAZ/YAP-activated cancer cells.
Reducing the serine availability complements the inhibition of the glutamine metabolism to block leukemia cell growth.
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor.
Control of nutrient stress-induced metabolic reprogramming by PKCζ in tumorigenesis.
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Wang LW, Shen H, Nobre L, Ersing I, Paulo JA, Trudeau S, Wang Z, Smith NA, Ma Y, Reinstadler B, Nomburg J, Sommermann T, Cahir-McFarland E, Gygi SP, Mootha VK, Weekes MP, Gewurz BE
Cell metabolism 2019 Sep 3;30(3):539-555.e11
Cell metabolism 2019 Sep 3;30(3):539-555.e11
Glutamine-utilizing transaminases are a metabolic vulnerability of TAZ/YAP-activated cancer cells.
Yang CS, Stampouloglou E, Kingston NM, Zhang L, Monti S, Varelas X
EMBO reports 2018 Jun;19(6)
EMBO reports 2018 Jun;19(6)
Reducing the serine availability complements the inhibition of the glutamine metabolism to block leukemia cell growth.
Polet F, Corbet C, Pinto A, Rubio LI, Martherus R, Bol V, Drozak X, Grégoire V, Riant O, Feron O
Oncotarget 2016 Jan 12;7(2):1765-76
Oncotarget 2016 Jan 12;7(2):1765-76
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor.
Krall AS, Xu S, Graeber TG, Braas D, Christofk HR
Nature communications 2016 Apr 29;7:11457
Nature communications 2016 Apr 29;7:11457
Control of nutrient stress-induced metabolic reprogramming by PKCζ in tumorigenesis.
Ma L, Tao Y, Duran A, Llado V, Galvez A, Barger JF, Castilla EA, Chen J, Yajima T, Porollo A, Medvedovic M, Brill LM, Plas DR, Riedl SJ, Leitges M, Diaz-Meco MT, Richardson AD, Moscat J
Cell 2013 Jan 31;152(3):599-611
Cell 2013 Jan 31;152(3):599-611
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.
Locasale JW, Grassian AR, Melman T, Lyssiotis CA, Mattaini KR, Bass AJ, Heffron G, Metallo CM, Muranen T, Sharfi H, Sasaki AT, Anastasiou D, Mullarky E, Vokes NI, Sasaki M, Beroukhim R, Stephanopoulos G, Ligon AH, Meyerson M, Richardson AL, Chin L, Wagner G, Asara JM, Brugge JS, Cantley LC, Vander Heiden MG
Nature genetics 2011 Jul 31;43(9):869-74
Nature genetics 2011 Jul 31;43(9):869-74
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Possemato R, Marks KM, Shaul YD, Pacold ME, Kim D, Birsoy K, Sethumadhavan S, Woo HK, Jang HG, Jha AK, Chen WW, Barrett FG, Stransky N, Tsun ZY, Cowley GS, Barretina J, Kalaany NY, Hsu PP, Ottina K, Chan AM, Yuan B, Garraway LA, Root DE, Mino-Kenudson M, Brachtel EF, Driggers EM, Sabatini DM
Nature 2011 Aug 18;476(7360):346-50
Nature 2011 Aug 18;476(7360):346-50
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: PSAT1 Antibody [H00029968-A01] - Analysis of PSAT1 expression in IMR-32 (Cat # L008V1).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: PSAT1 Antibody [H00029968-A01] - Analysis of PSAT1 expression in MES-SA/Dx5.
