TAS1R1

The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

Description

Taste 1 receptor member 1

Tissue specificity

Tissue enriched (testis)

Predicted location

Intracellular, Membrane

Protein family

G-protein coupled receptors
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Transporters

Chromosome

1 (6555307 - 6579755)

Ensembl ID

ENSG00000173662  (ver. 103.38)

Orthologs

Mouse Tas1r1: ENSMUSG00000028950

UniProt

Q7RTX1

neXtProt

NX_Q7RTX1

Human splice variants
Mouse splice variants

Protein structure