Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 12379-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12379-1-AP, RRID:AB_2186517
- Product name
- SF3B14 antibody
- Antibody type
- Polyclonal
- Description
- SF3B14 antibody (Cat. #12379-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references De novo PHF5A variants are associated with craniofacial abnormalities, developmental delay, and hypospadias.
Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex.
Harms FL, Dingemans AJM, Hempel M, Pfundt R, Bierhals T, Casar C, Müller C, Niermeijer JF, Fischer J, Jahn A, Hübner C, Majore S, Agolini E, Novelli A, van der Smagt J, Ernst R, van Binsbergen E, Mancini GMS, van Slegtenhorst M, Barakat TS, Wakeling EL, Kamath A, Downie L, Pais L, White SM, de Vries BBA, Kutsche K
Genetics in medicine : official journal of the American College of Medical Genetics 2023 Oct;25(10):100927
Genetics in medicine : official journal of the American College of Medical Genetics 2023 Oct;25(10):100927
Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex.
Teng T, Tsai JH, Puyang X, Seiler M, Peng S, Prajapati S, Aird D, Buonamici S, Caleb B, Chan B, Corson L, Feala J, Fekkes P, Gerard B, Karr C, Korpal M, Liu X, T Lowe J, Mizui Y, Palacino J, Park E, Smith PG, Subramanian V, Wu ZJ, Zou J, Yu L, Chicas A, Warmuth M, Larsen N, Zhu P
Nature communications 2017 May 25;8:15522
Nature communications 2017 May 25;8:15522
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The SF3B14 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SF3B14. This antibody recognizes human, mouse, rat antigen. The SF3B14 antibody has been validated for the following applications: ELISA, WB analysis.