Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 15042-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- AZI2/NAP1 antibody
- Antibody type
- Polyclonal
- Description
- AZI2/NAP1 antibody (Cat. #15042-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references AZI2 mediates TBK1 activation at unresolved selective autophagy cargo receptor complexes with implications for CD8 T-cell infiltration in breast cancer.
NAK-associated protein 1/NAP1 activates TBK1 to ensure accurate mitosis and cytokinesis.
Increased IKKϵ protein stability ensures efficient type I interferon responses in conditions of TBK1 deficiency.
FIP200 Suppresses Immune Checkpoint Therapy Responses in Breast Cancers by Limiting AZI2/TBK1/IRF Signaling Independent of Its Canonical Autophagy Function.
MAVS activates TBK1 and IKKε through TRAFs in NEMO dependent and independent manner.
Yeo SK, Haas M, Manupati K, Hao M, Yang F, Chen S, Guan JL
Autophagy 2024 Mar;20(3):525-540
Autophagy 2024 Mar;20(3):525-540
NAK-associated protein 1/NAP1 activates TBK1 to ensure accurate mitosis and cytokinesis.
Paul S, Sarraf SA, Nam KH, Zavar L, DeFoor N, Biswas SR, Fritsch LE, Yaron TM, Johnson JL, Huntsman EM, Cantley LC, Ordureau A, Pickrell AM
The Journal of cell biology 2024 Feb 5;223(2)
The Journal of cell biology 2024 Feb 5;223(2)
Increased IKKϵ protein stability ensures efficient type I interferon responses in conditions of TBK1 deficiency.
Wegner J, Hunkler C, Ciupka K, Hartmann G, Schlee M
Frontiers in immunology 2023;14:1073608
Frontiers in immunology 2023;14:1073608
FIP200 Suppresses Immune Checkpoint Therapy Responses in Breast Cancers by Limiting AZI2/TBK1/IRF Signaling Independent of Its Canonical Autophagy Function.
Okamoto T, Yeo SK, Hao M, Copley MR, Haas MA, Chen S, Guan JL
Cancer research 2020 Sep 1;80(17):3580-3592
Cancer research 2020 Sep 1;80(17):3580-3592
MAVS activates TBK1 and IKKε through TRAFs in NEMO dependent and independent manner.
Fang R, Jiang Q, Zhou X, Wang C, Guan Y, Tao J, Xi J, Feng JM, Jiang Z
PLoS pathogens 2017 Nov;13(11):e1006720
PLoS pathogens 2017 Nov;13(11):e1006720
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AZI2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AZI2. This antibody recognizes human,mouse,rat antigen. The AZI2 antibody has been validated for the following applications: ELISA, WB analysis.