Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB1740 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB1740, RRID:AB_1238048
- Product name
- UBQLN1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of UBQLN1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references MiR-200c inhibits autophagy and enhances radiosensitivity in breast cancer cells by targeting UBQLN1.
Interaction with a ubiquitin-like protein enhances the ubiquitination and degradation of hepatitis C virus RNA-dependent RNA polymerase.
Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation.
The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome.
Sun Q, Liu T, Yuan Y, Guo Z, Xie G, Du S, Lin X, Xu Z, Liu M, Wang W, Yuan Q, Chen L
International journal of cancer 2015 Mar 1;136(5):1003-12
International journal of cancer 2015 Mar 1;136(5):1003-12
Interaction with a ubiquitin-like protein enhances the ubiquitination and degradation of hepatitis C virus RNA-dependent RNA polymerase.
Gao L, Tu H, Shi ST, Lee KJ, Asanaka M, Hwang SB, Lai MM
Journal of virology 2003 Apr;77(7):4149-59
Journal of virology 2003 Apr;77(7):4149-59
Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation.
Mah AL, Perry G, Smith MA, Monteiro MJ
The Journal of cell biology 2000 Nov 13;151(4):847-62
The Journal of cell biology 2000 Nov 13;151(4):847-62
The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome.
Kleijnen MF, Shih AH, Zhou P, Kumar S, Soccio RE, Kedersha NL, Gill G, Howley PM
Molecular cell 2000 Aug;6(2):409-19
Molecular cell 2000 Aug;6(2):409-19
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The UBQLN1 polyclonal antibody (Cat # PAB1740) is used in Western blot to detect UBQLN1 in mouse liver tissue lysate.
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of UBQLN1 polyclonal antibody (Cat # PAB1740) in T-47D cell line lysates (35 ug/lane). UBQLN1 (arrow) was detected using the purified polyclonal antibody.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with UBQLN1 polyclonal antibody (Cat # PAB1740) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)