Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11223-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11223-1-AP, RRID:AB_2248839
- Product name
- HUS1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HUS1 antibody (Cat. #11223-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication.
DNA damage-induced translocation of mitochondrial factor HIGD1A into the nucleus regulates homologous recombination and radio/chemo-sensitivity.
Discovery and Validation of Novel Methylation Markers in Helicobacter pylori-Associated Gastric Cancer.
Succinylation at a key residue of FEN1 is involved in the DNA damage response to maintain genome stability.
HUS1 checkpoint clamp component (HUS1) is a potential tumor suppressor in primary hepatocellular carcinoma.
SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress.
Mackay HL, Stone HR, Ellis K, Ronson GE, Walker AK, Starowicz K, Garvin AJ, van Eijk P, Vaitsiankova A, Vijayendran S, Beesley JF, Petermann E, Brown EJ, Densham RM, Reed SH, Dobbs F, Saponaro M, Morris JR
bioRxiv : the preprint server for biology 2024 Jan 11;
bioRxiv : the preprint server for biology 2024 Jan 11;
DNA damage-induced translocation of mitochondrial factor HIGD1A into the nucleus regulates homologous recombination and radio/chemo-sensitivity.
Chen B, Xu F, Gao Y, Hu G, Zhu K, Lu H, Xu A, Chen S, Wu L, Zhao G
Oncogene 2022 Mar;41(13):1918-1930
Oncogene 2022 Mar;41(13):1918-1930
Discovery and Validation of Novel Methylation Markers in Helicobacter pylori-Associated Gastric Cancer.
Wang H, Li NS, He C, Xie C, Zhu Y, Lu NH, Hu Y
Disease markers 2021;2021:4391133
Disease markers 2021;2021:4391133
Succinylation at a key residue of FEN1 is involved in the DNA damage response to maintain genome stability.
Shi R, Wang Y, Gao Y, Xu X, Mao S, Xiao Y, Song S, Wang L, Tian B, Zhao Y, Hua Y, Xu H
American journal of physiology. Cell physiology 2020 Oct 1;319(4):C657-C666
American journal of physiology. Cell physiology 2020 Oct 1;319(4):C657-C666
HUS1 checkpoint clamp component (HUS1) is a potential tumor suppressor in primary hepatocellular carcinoma.
Zhou ZQ, Zhao JJ, Chen CL, Liu Y, Zeng JX, Wu ZR, Tang Y, Zhu Q, Weng DS, Xia JC
Molecular carcinogenesis 2019 Jan;58(1):76-87
Molecular carcinogenesis 2019 Jan;58(1):76-87
SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress.
Xu X, Shi R, Zheng L, Guo Z, Wang L, Zhou M, Zhao Y, Tian B, Truong K, Chen Y, Shen B, Hua Y, Xu H
Journal of molecular cell biology 2018 Oct 1;10(5):460-474
Journal of molecular cell biology 2018 Oct 1;10(5):460-474
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The HUS1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HUS1. This antibody recognizes human antigen. The HUS1 antibody has been validated for the following applications: ELISA, IHC analysis.