MPIG6B

This gene is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. The protein encoded by this gene is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Description

Megakaryocyte and platelet inhibitory receptor G6b

Tissue specificity

Tissue enhanced (lung, lymphoid tissue, skin)

Subcell location

Nucleoplasm, Endoplasmic reticulum, Golgi apparatus, Plasma membrane, Cytosol

Predicted location

Intracellular, Membrane

Protein family

Disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

6 (31718594 - 31726714)

Ensembl ID

ENSG00000204420  (ver. 103.38)

Orthologs

Mouse Mpig6b: ENSMUSG00000073414

UniProt

O95866

neXtProt

NX_O95866

Human splice variants
Mouse splice variants

Protein structure