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- Antibody Data
- Antigen structure
- References [11]
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- Product number
- HPA018002 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA018002, RRID:AB_1854802
- Product name
- Anti-SIGMAR1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human SIGMAR1, Gene description: sigma non-opioid intracellular receptor 1, Alternative Gene Names: OPRS1, SR-BP1, Validated applications: IHC, WB, Uniprot ID: Q99720, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus
Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors
PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment
Oxidative stress modulates rearrangement of endoplasmic reticulum-mitochondria contacts and calcium dysregulation in a Friedreich's ataxia model
Disruption of endoplasmic reticulum-mitochondria tethering proteins in post-mortem Alzheimer's disease brain
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases
Calcium mishandling in absence of primary mitochondrial dysfunction drives cellular pathology in Wolfram Syndrome
The endogenous subcellular localisations of the long chain fatty acid-activating enzymes ACSL3 and ACSL4 in sarcoma and breast cancer cells
STAT3 localizes to the ER, acting as a gatekeeper for ER-mitochondrion Ca2+ fluxes and apoptotic responses
Modeling tandem AAG8‐MEK inhibition in melanoma cells
The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation
Bertino F, Mukherjee D, Bonora M, Bagowski C, Nardelli J, Metani L, Zanin Venturini D, Chianese D, Santander N, Salaroglio I, Hentschel A, Quarta E, Genova T, McKinney A, Allocco A, Fiorito V, Petrillo S, Ammirata G, De Giorgio F, Dennis E, Allington G, Maier F, Shoukier M, Gloning K, Munaron L, Mussano F, Salsano E, Pareyson D, di Rocco M, Altruda F, Panagiotakos G, Kahle K, Gressens P, Riganti C, Pinton P, Roos A, Arnold T, Tolosano E, Chiabrando D
Cell Reports Medicine 2024;5(7):101647
Cell Reports Medicine 2024;5(7):101647
Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors
Yamato A, Nagano H, Gao Y, Matsuda T, Hashimoto N, Nakayama A, Yamagata K, Yokoyama M, Gong Y, Shi X, Zhahara S, Kono T, Taki Y, Furuki N, Nishimura M, Horiguchi K, Iwadate Y, Fukuyo M, Rahmutulla B, Kaneda A, Hasegawa Y, Kawashima Y, Ohara O, Ishikawa T, Kawakami E, Nakamura Y, Inoshita N, Yamada S, Fukuhara N, Nishioka H, Tanaka T
Communications Biology 2022;5(1)
Communications Biology 2022;5(1)
PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment
Missiroli S, Perrone M, Gafà R, Nicoli F, Bonora M, Morciano G, Boncompagni C, Marchi S, Lebiedzinska-Arciszewska M, Vezzani B, Lanza G, Kricek F, Borghi A, Fiorica F, Ito K, Wieckowski M, Di Virgilio F, Abelli L, Pinton P, Giorgi C
Cell Death & Differentiation 2022;30(2):429-441
Cell Death & Differentiation 2022;30(2):429-441
Oxidative stress modulates rearrangement of endoplasmic reticulum-mitochondria contacts and calcium dysregulation in a Friedreich's ataxia model
Rodríguez L, Calap-Quintana P, Lapeña-Luzón T, Pallardó F, Schneuwly S, Navarro J, Gonzalez-Cabo P
Redox Biology 2020;37
Redox Biology 2020;37
Disruption of endoplasmic reticulum-mitochondria tethering proteins in post-mortem Alzheimer's disease brain
Lau D, Paillusson S, Hartopp N, Rupawala H, Mórotz G, Gomez-Suaga P, Greig J, Troakes C, Noble W, Miller C
Neurobiology of Disease 2020;143
Neurobiology of Disease 2020;143
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases
Genovese I, Giamogante F, Barazzuol L, Battista T, Fiorillo A, Vicario M, D’Alessandro G, Cipriani R, Limatola C, Rossi D, Sorrentino V, Poser E, Mosca L, Squitieri F, Perluigi M, Arena A, van Petegem F, Tito C, Fazi F, Giorgi C, Calì T, Ilari A, Colotti G
Cell Death & Disease 2020;11(10)
Cell Death & Disease 2020;11(10)
Calcium mishandling in absence of primary mitochondrial dysfunction drives cellular pathology in Wolfram Syndrome
La Morgia C, Maresca A, Amore G, Gramegna L, Carbonelli M, Scimonelli E, Danese A, Patergnani S, Caporali L, Tagliavini F, Del Dotto V, Capristo M, Sadun F, Barboni P, Savini G, Evangelisti S, Bianchini C, Valentino M, Liguori R, Tonon C, Giorgi C, Pinton P, Lodi R, Carelli V
Scientific Reports 2020;10(1)
Scientific Reports 2020;10(1)
The endogenous subcellular localisations of the long chain fatty acid-activating enzymes ACSL3 and ACSL4 in sarcoma and breast cancer cells
Radif Y, Ndiaye H, Kalantzi V, Jacobs R, Hall A, Minogue S, Waugh M
Molecular and Cellular Biochemistry 2018;448(1-2):275-286
Molecular and Cellular Biochemistry 2018;448(1-2):275-286
STAT3 localizes to the ER, acting as a gatekeeper for ER-mitochondrion Ca2+ fluxes and apoptotic responses
Avalle L, Camporeale A, Morciano G, Caroccia N, Ghetti E, Orecchia V, Viavattene D, Giorgi C, Pinton P, Poli V
Cell Death & Differentiation 2018;26(5):932-942
Cell Death & Differentiation 2018;26(5):932-942
Modeling tandem AAG8‐MEK inhibition in melanoma cells
Sun B, Kawahara M, Nagamune T
Cancer Medicine 2014;3(3):710-718
Cancer Medicine 2014;3(3):710-718
The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation
Chiabrando D, Marro S, Mercurio S, Giorgi C, Petrillo S, Vinchi F, Fiorito V, Fagoonee S, Camporeale A, Turco E, Merlo G, Silengo L, Altruda F, Pinton P, Tolosano E
Journal of Clinical Investigation 2012;122(12):4569-4579
Journal of Clinical Investigation 2012;122(12):4569-4579
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