Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 10636-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10636-1-AP, RRID:AB_2092679
- Product name
- DLK1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DLK1 antibody (Cat. #10636-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Single-cell landscape of undifferentiated pleomorphic sarcoma.
Identifying a dynamic transcriptomic landscape of the cynomolgus macaque placenta during pregnancy at single-cell resolution.
Spatiotemporal transcriptome atlas reveals the regional specification of the developing human brain.
LAMC1-mediated preadipocytes differentiation promoted peritoneum pre-metastatic niche formation and gastric cancer metastasis.
Dopamine-related oxidative stress and mitochondrial dysfunction in dopaminergic neurons differentiated from deciduous teeth-derived stem cells of children with Down syndrome.
Vitamin C attenuates predisposition to high-fat diet-induced metabolic dysregulation in GLUT10-deficient mouse model.
A Na(+)/K(+) ATPase Pump Regulates Chondrocyte Differentiation and Bone Length Variation in Mice.
Visceral adipogenesis inhibited by Pref-1 is associated with peritoneal angiogenesis.
TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma.
Abnormally localized DLK1 interacts with NCOR1 in non-small cell lung cancer cell nuclear.
GREB1 induced by Wnt signaling promotes development of hepatoblastoma by suppressing TGFβ signaling.
The miR-181d-regulated metalloproteinase Adamts1 enzymatically impairs adipogenesis via ECM remodeling.
Dietary vitamin A restriction affects adipocyte differentiation and fatty acid composition of intramuscular fat in Iberian pigs.
DLK1 promotes lung cancer cell invasion through upregulation of MMP9 expression depending on Notch signaling.
Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice.
Delta-like 1 homologue is a hypothalamus-enriched protein that is present in orexin-containing neurones of the lateral hypothalamic area.
Paternal uniparental disomy 14 and related disorders: placental gene expression analyses and histological examinations.
Recovery of mature hepatocytic phenotype following bile ductular transdifferentiation of rat hepatocytes in vitro.
Macrophage-secreted factors promote a profibrotic phenotype in human preadipocytes.
Gene dosage effects of the imprinted delta-like homologue 1 (dlk1/pref1) in development: implications for the evolution of imprinting.
CLA differently regulates adipogenesis in stromal vascular cells from porcine subcutaneous adipose and skeletal muscle.
Lu Y, Chen D, Wang B, Chai W, Yan M, Chen Y, Zhan Y, Yang R, Zhou E, Dai S, Li Y, Dong R, Zheng B
Oncogene 2024 May;43(18):1353-1368
Oncogene 2024 May;43(18):1353-1368
Identifying a dynamic transcriptomic landscape of the cynomolgus macaque placenta during pregnancy at single-cell resolution.
Jiang X, Zhai J, Xiao Z, Wu X, Zhang D, Wan H, Xu Y, Qi L, Wang M, Yu D, Liu Y, Wu H, Sun R, Xia S, Yu K, Guo J, Wang H
Developmental cell 2023 May 8;58(9):806-821.e7
Developmental cell 2023 May 8;58(9):806-821.e7
Spatiotemporal transcriptome atlas reveals the regional specification of the developing human brain.
Li Y, Li Z, Wang C, Yang M, He Z, Wang F, Zhang Y, Li R, Gong Y, Wang B, Fan B, Wang C, Chen L, Li H, Shi P, Wang N, Wei Z, Wang YL, Jin L, Du P, Dong J, Jiao J
Cell 2023 Dec 21;186(26):5892-5909.e22
Cell 2023 Dec 21;186(26):5892-5909.e22
LAMC1-mediated preadipocytes differentiation promoted peritoneum pre-metastatic niche formation and gastric cancer metastasis.
Fang Y, Dou R, Huang S, Han L, Fu H, Yang C, Song J, Zheng J, Zhang X, Liu K, Xiang Z, Zhang X, Wang S, Xiong B
International journal of biological sciences 2022;18(7):3082-3101
International journal of biological sciences 2022;18(7):3082-3101
Dopamine-related oxidative stress and mitochondrial dysfunction in dopaminergic neurons differentiated from deciduous teeth-derived stem cells of children with Down syndrome.
Sun X, Kato H, Sato H, Han X, Hirofuji Y, Kato TA, Sakai Y, Ohga S, Fukumoto S, Masuda K
FASEB bioAdvances 2022 Jul;4(7):454-467
FASEB bioAdvances 2022 Jul;4(7):454-467
Vitamin C attenuates predisposition to high-fat diet-induced metabolic dysregulation in GLUT10-deficient mouse model.
Jiang CL, Tsao CY, Lee YC
Genes & nutrition 2022 Jul 16;17(1):10
Genes & nutrition 2022 Jul 16;17(1):10
A Na(+)/K(+) ATPase Pump Regulates Chondrocyte Differentiation and Bone Length Variation in Mice.
Marchini M, Ashkin MR, Bellini M, Sun MM, Workentine ML, Okuyan HM, Krawetz R, Beier F, Rolian C
Frontiers in cell and developmental biology 2021;9:708384
Frontiers in cell and developmental biology 2021;9:708384
Visceral adipogenesis inhibited by Pref-1 is associated with peritoneal angiogenesis.
Jing R, Feng H, Jiang N, Zhang H, Fang W, Ni Z, Yuan J
Nephrology (Carlton, Vic.) 2020 Mar;25(3):248-254
Nephrology (Carlton, Vic.) 2020 Mar;25(3):248-254
TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma.
Zhang J, Liu P, Tao J, Wang P, Zhang Y, Song X, Che L, Sumazin P, Ribback S, Kiss A, Schaff Z, Cigliano A, Dombrowski F, Cossu C, Pascale RM, Calvisi DF, Monga SP, Chen X
The American journal of pathology 2019 May;189(5):1077-1090
The American journal of pathology 2019 May;189(5):1077-1090
Abnormally localized DLK1 interacts with NCOR1 in non-small cell lung cancer cell nuclear.
Tan J, Zhang S, Li L, Mu J, Wang Z, Zhang L, Jiang M, Li W, Yang X, Liu Y, Gao Y
Bioscience reports 2019 Dec 20;39(12)
Bioscience reports 2019 Dec 20;39(12)
GREB1 induced by Wnt signaling promotes development of hepatoblastoma by suppressing TGFβ signaling.
Matsumoto S, Yamamichi T, Shinzawa K, Kasahara Y, Nojima S, Kodama T, Obika S, Takehara T, Morii E, Okuyama H, Kikuchi A
Nature communications 2019 Aug 28;10(1):3882
Nature communications 2019 Aug 28;10(1):3882
The miR-181d-regulated metalloproteinase Adamts1 enzymatically impairs adipogenesis via ECM remodeling.
Chen SZ, Ning LF, Xu X, Jiang WY, Xing C, Jia WP, Chen XL, Tang QQ, Huang HY
Cell death and differentiation 2016 Nov 1;23(11):1778-1791
Cell death and differentiation 2016 Nov 1;23(11):1778-1791
Dietary vitamin A restriction affects adipocyte differentiation and fatty acid composition of intramuscular fat in Iberian pigs.
Ayuso M, Óvilo C, Rodríguez-Bertos A, Rey AI, Daza A, Fenández A, González-Bulnes A, López-Bote CJ, Isabel B
Meat science 2015 Oct;108:9-16
Meat science 2015 Oct;108:9-16
DLK1 promotes lung cancer cell invasion through upregulation of MMP9 expression depending on Notch signaling.
Li L, Tan J, Zhang Y, Han N, Di X, Xiao T, Cheng S, Gao Y, Liu Y
PloS one 2014;9(3):e91509
PloS one 2014;9(3):e91509
Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice.
Tao J, Calvisi DF, Ranganathan S, Cigliano A, Zhou L, Singh S, Jiang L, Fan B, Terracciano L, Armeanu-Ebinger S, Ribback S, Dombrowski F, Evert M, Chen X, Monga SPS
Gastroenterology 2014 Sep;147(3):690-701
Gastroenterology 2014 Sep;147(3):690-701
Delta-like 1 homologue is a hypothalamus-enriched protein that is present in orexin-containing neurones of the lateral hypothalamic area.
Meister B, Perez-Manso M, Daraio T
Journal of neuroendocrinology 2013 Jul;25(7):617-25
Journal of neuroendocrinology 2013 Jul;25(7):617-25
Paternal uniparental disomy 14 and related disorders: placental gene expression analyses and histological examinations.
Kagami M, Matsuoka K, Nagai T, Yamanaka M, Kurosawa K, Suzumori N, Sekita Y, Miyado M, Matsubara K, Fuke T, Kato F, Fukami M, Ogata T
Epigenetics 2012 Oct;7(10):1142-50
Epigenetics 2012 Oct;7(10):1142-50
Recovery of mature hepatocytic phenotype following bile ductular transdifferentiation of rat hepatocytes in vitro.
Sone M, Nishikawa Y, Nagahama Y, Kumagai E, Doi Y, Omori Y, Yoshioka T, Tokairin T, Yoshida M, Sugiyama T, Enomoto K
The American journal of pathology 2012 Dec;181(6):2094-104
The American journal of pathology 2012 Dec;181(6):2094-104
Macrophage-secreted factors promote a profibrotic phenotype in human preadipocytes.
Keophiphath M, Achard V, Henegar C, Rouault C, Clément K, Lacasa D
Molecular endocrinology (Baltimore, Md.) 2009 Jan;23(1):11-24
Molecular endocrinology (Baltimore, Md.) 2009 Jan;23(1):11-24
Gene dosage effects of the imprinted delta-like homologue 1 (dlk1/pref1) in development: implications for the evolution of imprinting.
da Rocha ST, Charalambous M, Lin SP, Gutteridge I, Ito Y, Gray D, Dean W, Ferguson-Smith AC
PLoS genetics 2009 Feb;5(2):e1000392
PLoS genetics 2009 Feb;5(2):e1000392
CLA differently regulates adipogenesis in stromal vascular cells from porcine subcutaneous adipose and skeletal muscle.
Zhou X, Li D, Yin J, Ni J, Dong B, Zhang J, Du M
Journal of lipid research 2007 Aug;48(8):1701-9
Journal of lipid research 2007 Aug;48(8):1701-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse placenta tissue were subjected to SDS PAGE followed by western blot with 10636-1-AP(DLK1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 10636-1-AP(DLK1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DLK1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DLK1. This antibody recognizes human,mouse,rat antigen. The DLK1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.