BS8362
antibody from Bioworld Technology, Inc
Targeting: PNPLA3
adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon
Antibody data
- Antibody Data
- Antigen structure
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- Comments [0]
- Validations [0]
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- Product number
- BS8362 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- PNPLA3 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human PNPLA3.
- Description
- ADPN, a member of the Adiponutrin family, displays lipase activity that is dependent upon the presence of an activated serine residue. D-glucose elicits a 7-fold increase in ADPN mRNA levels, and insulin has a slight effect on ADPN expression in the presence or absence of glucose. The glucose-induced increase in ADPN expression can be reversed by factors known to raise intracellular cAMP. mRNA ADPN levels are negatively correlated with fasting glucose levels and subjects with high ADPN mRNA levels have increased insulin sensitivity, implicating ADPN in obesity and diabetes. ADPN gene expression in humans is highly regulated by changes in energy balance. In mice adipocytes, ADPN parallels the expression of fatty acid synthase (FAS) and Srebp1c, a variant of Srebp1.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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