BS8770

antibody from Bioworld Technology, Inc
Targeting: METTL7B ALDI, MGC17301
Provider product page for BS8770
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8770 - Provider product page
Provider
Bioworld Technology, Inc
Product name
METTL7B polyclonal antibody
Antibody type
Polyclonal
Antigen
Methyltransferase-like protein 7B; METTL7B; UNQ594/PRO1180
Description
METTL7B (methyltransferase-like protein 7B) is a 244 amino acid protein belonging to the methyltransferase superfamily. METTL7B is believed to have methyltransferase activity, wherein METTL7B catalyzes the transfer of a methyl group from one compound to another. The gene that encodes METTL7B maps to chromosome 12 which makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
METTL7B protein structure - BS8770 shown in red.