Antibody data
- Antibody Data
- Antigen structure
- References [32]
- Comments [0]
- Validations [0]
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Validation data
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- Product number
- 67934-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- AGO2 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated AGO2 antibody (Cat. #67934-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1G2H12
- Vial size
- 20ul, 150ul
Submitted references CircPRMT5 promotes progression of osteosarcoma by recruiting CNBP to regulate the translation and stability of CDK6 mRNA.
CircSFMBT2 Plays an Oncogenic Role in Lung Adenocarcinoma Depending on the miR-1305/SALL4 Axis.
circPVT1 promotes silica-induced epithelial-mesenchymal transition by modulating the miR-497-5p/TCF3 axis.
miR615-3p inhibited FBLN1 and osteogenic differentiation of umbilical cord mesenchymal stem cells by associated with YTHDF2 in a m(6)A-miRNA interaction manner.
CircUGGT2 downregulation by METTL14-dependent m(6)A modification suppresses gastric cancer progression and cisplatin resistance through interaction with miR-186-3p/MAP3K9 axis.
Circular RNA circLIFR suppresses papillary thyroid cancer progression by modulating the miR-429/TIMP2 axis.
LSM14B coordinates protein component expression in the P-body and controls oocyte maturation.
Hsa_circ_0020134 promotes liver metastasis of colorectal cancer through the miR-183-5p-PFN2-TGF-β/Smad axis.
Hsa_circ_0050900 affects ferroptosis in intrahepatic cholangiocarcinoma cells by targeting hsa‑miR-605‑3p to regulate SLC3A2.
Long non-coding RNA small nucleolar RNA host gene 29 drives chronic myeloid leukemia progression via microRNA-483-3p/Casitas B-lineage Lymphoma axis-mediated activation of the phosphoinositide 3-kinase/Akt pathway.
An essential role for the RNA helicase DDX6 in NMDA receptor-dependent gene silencing and dendritic spine shrinkage.
Upregulated LncRNA H19 Sponges MiR-106a-5p and Contributes to Aldosterone-Induced Vascular Calcification via Activating the Runx2-Dependent Pathway.
Lnc‑RGS5 sponges miR‑542‑5p to promote FoxM1/VEGFA signaling and breast cancer cell proliferation.
CircABPD1 alleviates oxidative lung injury of bronchopulmonary dysplasia through regulating miR-330-3p/HIF1α axis.
Circ_0001589/miR-1248/HMGB1 axis enhances EMT-mediated metastasis and cisplatin resistance in cervical cancer.
A novel feedback regulated loop of circRRM2-IGF2BP1-MYC promotes breast cancer metastasis.
Exosomal MFI2-AS1 sponge miR-107 promotes non-small cell lung cancer progression through NFAT5.
ELF1 suppresses autophagy to reduce cisplatin resistance via the miR-152-3p/NCAM1/ERK axis in lung cancer cells.
The regulatory role and mechanism of lncTUG1 on cartilage apoptosis and inflammation in osteoarthritis.
LncRNA BC promotes lung adenocarcinoma progression by modulating IMPAD1 alternative splicing.
LncRNA PEG11as aggravates cerebral ischemia/reperfusion injury after ischemic stroke through miR-342-5p/PFN1 axis.
CircZBTB46 Protects Acute Myeloid Leukemia Cells from Ferroptotic Cell Death by Upregulating SCD.
saKLK1-374 is more difficult to induce KLK1 expression in normal prostate cell lines than that in prostate cancer cell lines: Rethinking the universality of RNA activation.
LncRNA MIR200CHG inhibits EMT in gastric cancer by stabilizing miR-200c from target-directed miRNA degradation.
A novel circular RNA, circMAML3, promotes tumor progression of prostate cancer by regulating miR-665/MAPK8IP2 axis.
Circ_0000235 targets MCT4 to promote glycolysis and progression of bladder cancer by sponging miR-330-5p.
A 5`-tRNA Derived Fragment NamedtiRNA-Val-CAC-001 Works as a Suppressor in Gastric Cancer.
Tumor promoting effect of circ_002172 associates with induced immune escape in breast cancer via the miR-296-5p/CXCL12 axis.
Evaluation of Early Biomarkers of Atherosclerosis Associated with Polychlorinated Biphenyl Exposure: An in Vitro and in Vivo Study.
Long Noncoding RNA lncNDEPD1 Regulates PD-1 Expression via miR-3619-5p in CD8(+) T Cells.
New Insights into Mitochondrial-Nuclear Interactions Revealed through Analysis of Small RNAs.
Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.
Liu Y, Jiang H, Hu K, Zou H, Zhang W, Liu J, Jian X
PloS one 2024;19(4):e0298947
PloS one 2024;19(4):e0298947
CircSFMBT2 Plays an Oncogenic Role in Lung Adenocarcinoma Depending on the miR-1305/SALL4 Axis.
Zhao X, Xing X, Wu Y
Biochemical genetics 2024 Oct;62(5):3485-3503
Biochemical genetics 2024 Oct;62(5):3485-3503
circPVT1 promotes silica-induced epithelial-mesenchymal transition by modulating the miR-497-5p/TCF3 axis.
Zhou S, Li Y, Sun W, Ma D, Liu Y, Cheng D, Li G, Ni C
Journal of biomedical research 2024 Mar 26;38(2):163-174
Journal of biomedical research 2024 Mar 26;38(2):163-174
miR615-3p inhibited FBLN1 and osteogenic differentiation of umbilical cord mesenchymal stem cells by associated with YTHDF2 in a m(6)A-miRNA interaction manner.
Yang H, Wang W, Liu H, Zhang C, Cao Y, Long L, Han X, Wang Y, Yan F, Li G, Zhu M, Jin L, Fan Z
Cell proliferation 2024 Jun;57(6):e13607
Cell proliferation 2024 Jun;57(6):e13607
CircUGGT2 downregulation by METTL14-dependent m(6)A modification suppresses gastric cancer progression and cisplatin resistance through interaction with miR-186-3p/MAP3K9 axis.
Chen XY, Yang YL, Yu Y, Chen ZY, Fan HN, Zhang J, Zhu JS
Pharmacological research 2024 Jun;204:107206
Pharmacological research 2024 Jun;204:107206
Circular RNA circLIFR suppresses papillary thyroid cancer progression by modulating the miR-429/TIMP2 axis.
Zhang F, Li J, Xu J, Jiang X, Chen S, Nasser QA
Journal of cancer research and clinical oncology 2024 Jun 25;150(6):323
Journal of cancer research and clinical oncology 2024 Jun 25;150(6):323
LSM14B coordinates protein component expression in the P-body and controls oocyte maturation.
Zhang H, Zhang T, Wan X, Chen C, Wang S, Qin D, Li L, Yu L, Wu X
Journal of genetics and genomics = Yi chuan xue bao 2024 Jan;51(1):48-60
Journal of genetics and genomics = Yi chuan xue bao 2024 Jan;51(1):48-60
Hsa_circ_0020134 promotes liver metastasis of colorectal cancer through the miR-183-5p-PFN2-TGF-β/Smad axis.
Yu JH, Tan JN, Zhong GY, Zhong L, Hou D, Ma S, Wang PL, Zhang ZH, Lu XQ, Yang B, Zhou SN, Han FH
Translational oncology 2024 Jan;39:101823
Translational oncology 2024 Jan;39:101823
Hsa_circ_0050900 affects ferroptosis in intrahepatic cholangiocarcinoma cells by targeting hsa‑miR-605‑3p to regulate SLC3A2.
Shi X, Yang J, Wang M, Xia L, Zhang L, Qiao S
Oncology letters 2024 Jan;27(1):2
Oncology letters 2024 Jan;27(1):2
Long non-coding RNA small nucleolar RNA host gene 29 drives chronic myeloid leukemia progression via microRNA-483-3p/Casitas B-lineage Lymphoma axis-mediated activation of the phosphoinositide 3-kinase/Akt pathway.
Feng X, Yang L, Liu X, Liu M, Liu L, Liu J, Luo J
Medical oncology (Northwood, London, England) 2024 Jan 22;41(2):60
Medical oncology (Northwood, London, England) 2024 Jan 22;41(2):60
An essential role for the RNA helicase DDX6 in NMDA receptor-dependent gene silencing and dendritic spine shrinkage.
Perooli FM, Wilkinson KA, Pring K, Hanley JG
Scientific reports 2024 Feb 6;14(1):3066
Scientific reports 2024 Feb 6;14(1):3066
Upregulated LncRNA H19 Sponges MiR-106a-5p and Contributes to Aldosterone-Induced Vascular Calcification via Activating the Runx2-Dependent Pathway.
Li XZ, Xiong ZC, Zhang SL, Hao QY, Liu ZY, Zhang HF, Wang JF, Gao JW, Liu PM
Arteriosclerosis, thrombosis, and vascular biology 2023 Sep;43(9):1684-1699
Arteriosclerosis, thrombosis, and vascular biology 2023 Sep;43(9):1684-1699
Lnc‑RGS5 sponges miR‑542‑5p to promote FoxM1/VEGFA signaling and breast cancer cell proliferation.
Song J, Tang Y, Song F
International journal of oncology 2023 Oct;63(4)
International journal of oncology 2023 Oct;63(4)
CircABPD1 alleviates oxidative lung injury of bronchopulmonary dysplasia through regulating miR-330-3p/HIF1α axis.
Li H, Ma K, Dou H, Liu L, Qian Y, Li S, Chen J, Han S, Gu X, Yin J
The international journal of biochemistry & cell biology 2023 Oct;163:106464
The international journal of biochemistry & cell biology 2023 Oct;163:106464
Circ_0001589/miR-1248/HMGB1 axis enhances EMT-mediated metastasis and cisplatin resistance in cervical cancer.
Ma T, Guo J, Han J, Li L, Ren Y, Huang J, Diao G, Zheng X, Zheng Y
Molecular carcinogenesis 2023 Nov;62(11):1645-1658
Molecular carcinogenesis 2023 Nov;62(11):1645-1658
A novel feedback regulated loop of circRRM2-IGF2BP1-MYC promotes breast cancer metastasis.
Hao R, Zhang L, Si Y, Zhang P, Wang Y, Li B, Hu J, Qi Y
Cancer cell international 2023 Mar 25;23(1):54
Cancer cell international 2023 Mar 25;23(1):54
Exosomal MFI2-AS1 sponge miR-107 promotes non-small cell lung cancer progression through NFAT5.
Xu J, Wang H, Shi B, Li N, Xu G, Yan X, Xu L
Cancer cell international 2023 Mar 18;23(1):51
Cancer cell international 2023 Mar 18;23(1):51
ELF1 suppresses autophagy to reduce cisplatin resistance via the miR-152-3p/NCAM1/ERK axis in lung cancer cells.
Zhao L, Wu X, Zhang Z, Fang L, Yang B, Li Y
Cancer science 2023 Jun;114(6):2650-2663
Cancer science 2023 Jun;114(6):2650-2663
The regulatory role and mechanism of lncTUG1 on cartilage apoptosis and inflammation in osteoarthritis.
Liu NN, Huang YP, Shao YB, Fan XF, Sun HY, Wang TR, Yao T, Chen XY
Arthritis research & therapy 2023 Jun 20;25(1):106
Arthritis research & therapy 2023 Jun 20;25(1):106
LncRNA BC promotes lung adenocarcinoma progression by modulating IMPAD1 alternative splicing.
Chen QW, Cai QQ, Yang Y, Dong S, Liu YY, Chen ZY, Kang CL, Qi B, Dong YW, Wu W, Zhuang LP, Shen YH, Meng ZQ, Wu XZ
Clinical and translational medicine 2023 Jan;13(1):e1129
Clinical and translational medicine 2023 Jan;13(1):e1129
LncRNA PEG11as aggravates cerebral ischemia/reperfusion injury after ischemic stroke through miR-342-5p/PFN1 axis.
Yu Z, Zhu M, Shu D, Zhang R, Xiang Z, Jiang A, Liu S, Zhang C, Yuan Q, Hu X
Life sciences 2023 Jan 15;313:121276
Life sciences 2023 Jan 15;313:121276
CircZBTB46 Protects Acute Myeloid Leukemia Cells from Ferroptotic Cell Death by Upregulating SCD.
Long F, Lin Z, Long Q, Lu Z, Zhu K, Zhao M, Yang M
Cancers 2023 Jan 11;15(2)
Cancers 2023 Jan 11;15(2)
saKLK1-374 is more difficult to induce KLK1 expression in normal prostate cell lines than that in prostate cancer cell lines: Rethinking the universality of RNA activation.
Zhang M, Lin D, Luo C, Wei P, Cui K, Chen K, Chen Z
Biochemical and biophysical research communications 2023 Feb 5;643:157-168
Biochemical and biophysical research communications 2023 Feb 5;643:157-168
LncRNA MIR200CHG inhibits EMT in gastric cancer by stabilizing miR-200c from target-directed miRNA degradation.
Zhu Y, Huang C, Zhang C, Zhou Y, Zhao E, Zhang Y, Pan X, Huang H, Liao W, Wang X
Nature communications 2023 Dec 8;14(1):8141
Nature communications 2023 Dec 8;14(1):8141
A novel circular RNA, circMAML3, promotes tumor progression of prostate cancer by regulating miR-665/MAPK8IP2 axis.
Zhenhao Z, Ru C, Xiaofeng C, Heng Y, Gongxian W
Cell death discovery 2023 Dec 14;9(1):455
Cell death discovery 2023 Dec 14;9(1):455
Circ_0000235 targets MCT4 to promote glycolysis and progression of bladder cancer by sponging miR-330-5p.
Zhong J, Xu A, Xu P, Su M, Wang P, Liu Z, Li B, Liu C, Jiang N
Cell death discovery 2023 Aug 2;9(1):283
Cell death discovery 2023 Aug 2;9(1):283
A 5`-tRNA Derived Fragment NamedtiRNA-Val-CAC-001 Works as a Suppressor in Gastric Cancer.
Zheng J, Li C, Zhu Z, Yang F, Wang X, Jiang P, Yan F
Cancer management and research 2022;14:2323-2337
Cancer management and research 2022;14:2323-2337
Tumor promoting effect of circ_002172 associates with induced immune escape in breast cancer via the miR-296-5p/CXCL12 axis.
Li P, Ren X, Zheng Y, Sun J, Ye G
International immunopharmacology 2022 May;106:108530
International immunopharmacology 2022 May;106:108530
Evaluation of Early Biomarkers of Atherosclerosis Associated with Polychlorinated Biphenyl Exposure: An in Vitro and in Vivo Study.
Yang B, Ye Z, Wang Y, Guo H, Lehmler HJ, Huang R, Song E, Song Y
Environmental health perspectives 2022 Mar;130(3):37011
Environmental health perspectives 2022 Mar;130(3):37011
Long Noncoding RNA lncNDEPD1 Regulates PD-1 Expression via miR-3619-5p in CD8(+) T Cells.
Cheng S, Li F, Qin H, Ping Y, Zhao Q, Gao Q, Song M, Qu J, Shan J, Zhang K, Zhang Z, Lian J, Liu S, Wang L, Zhang Y
Journal of immunology (Baltimore, Md. : 1950) 2022 Mar 15;208(6):1483-1492
Journal of immunology (Baltimore, Md. : 1950) 2022 Mar 15;208(6):1483-1492
New Insights into Mitochondrial-Nuclear Interactions Revealed through Analysis of Small RNAs.
Pozzi A, Dowling DK
Genome biology and evolution 2022 Feb 4;14(2)
Genome biology and evolution 2022 Feb 4;14(2)
Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.
Peng T, He Y, Wang T, Yu J, Ma X, Zhou Z, Sheng Y, Li L, Peng H, Li S, Zou J, Yuan Y, Zhao Y, Shi H, Li F, Liu W, Hu K, Lu X, Zhang G, Wang F
Journal of medicinal chemistry 2022 Aug 25;65(16):11010-11033
Journal of medicinal chemistry 2022 Aug 25;65(16):11010-11033
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