Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [95]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 67934-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- AGO2 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated AGO2 antibody (Cat. #67934-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1G2H12
- Vial size
- 20ul, 150ul
Submitted references Circular RNA circPLXNC1 functions as an inhibitor of senescence by regulating autophagy in osteoarthritis.
tRF-Ser-TGA-011 impedes gastric cancer progression by targeting the MAP3K13/JNK signaling cascade.
Scutellarin mediates cell cycle arrest and apoptosis in liver cancer through a novel circSRBD1/miR-2682-5p/ESR1 ceRNA axis.
The circTIMP2/miR-106a/TIMP2 tumor-suppressive axis versus tumor-derived exosomal counteraction in gastric cancer.
Diagnostic Value of miR-1225-5p in Acute Coronary Syndrome and its Mechanism in ox-LDL Induced Human Coronary Artery Endothelial Cells Injury.
EIF4A3/circPTGR1/miR-4725-5p positive- feedback loop promotes colorectal cancer progression via FAK/AKT signaling pathway.
miR-432 Exacerbates Obesity-Induced Dysregulation of Glucose and Lipid Homeostasis.
Circular RNA circSCMH1 regulates glycolysis to inhibit gastric cancer metastasis via miR-296-3p/HSPB7-GLUT3 axis.
Pelargonidin-3-O-Glucoside Restores Nitric Oxide Production via Interaction with circHMGCS1 to Ameliorate Endothelial Dysfunction.
RP13-516M14.1 Regulates Autophagy Through miR-429 via Both a ceRNA Network and Direct Interaction.
CircASH1L inhibits ferroptosis and enhances cisplatin resistance by sponging miR-515-5p to regulate cell cycle-related CDCA7/RRM2 in ovarian cancer cells.
METTL3-mediated m(6)A methylation of lncRNA PVT1 promotes the progression of oral squamous cell carcinoma via the miR-185-5p/SERPINB4 axis.
LINC00152 knockdown exerts repressive effects on epithelial-mesenchymal transition in bladder cancer.
Avian leukosis virus subgroup J evades innate immunity by activating miR-155 to dually target TRAF3 and STAT1.
Hsa_circ_0005325 Regulates the Proliferation, Apoptosis, Colony Formation, Migration, and Angiogenesis-Promoting Behavior of Oral Squamous Cell Carcinoma Cells Through the miR-433-3p/HMGA2 Axis.
Astragaloside IV Inhibits Lung Injury and Fibrosis Induced by PM2.5 by Targeting RUNX1 Through miR-362-3p.
Gastric cancer-derived exosomal miR-196a-5p remodels the pre-metastatic niche for peritoneal dissemination.
M2 macrophage-derived exosomes promote cell proliferation, migration and EMT of non-small cell lung cancer by secreting miR-155-5p.
HOTAIR, a ferroptosis-related gene, promotes malignant behavior of breast cancer via sponging miR-206.
Tie2-expressing monocytes/macrophages promote angiogenesis in chronically ischaemic brain tissue.
Inhibition of hsa_circ_0003314 contributes to trophoblast cell migration and invasion and inhibits pyroptosis in preeclampsia.
Long noncoding RNA SNHG5 promotes 5-fluorouracil resistance in colorectal cancer by regulating miR-26b/p-glycoprotein axis.
Uncarboxylated osteocalcin induced miR-143-3p targets SP7 and activates PI3K/Akt signaling in TNBC cells to promote invasion and migration.
CircFak promotes mechanical force-induced osteogenesis via FAK/AKT phosphorylation.
CircMRP4 orchestrates podocytes injury via the miR-499-5p/RRAGB/mTORC1 axis in diabetic kidney disease.
Study on the mechanism of hsa_circ_0074763 regulating the miR-3667-3P/ACSL4 axis in liver fibrosis.
Psychological stress-induced ALKBH5 deficiency promotes tumour innervation and pancreatic cancer via extracellular vesicle transfer of RNA.
m6A reader IGF2BP2-stabilized lncRNA LHX1-DT inhibits renal cell carcinoma (RCC) cell proliferation and invasion by sponging miR-590-5p.
LNP-enclosed NamiRNA inhibits pancreatic cancer proliferation and migration via dual pathways.
CircYAP1 inhibits osteosarcoma progression through the miR-135b-5p/FRK axis.
N6-methyladenosine-modified circQKI inhibits prostate cancer docetaxel-sensitivity via miR-188-3p/Beclin-1 pathway.
Exosome miR-199a-5p modulated vascular remodeling and inflammatory infiltration of Takayasu's arteritis.
Long non-coding RNA MIR4435-2HG modulates pancreatic cancer stem cells and chemosensitivity to gemcitabine by targeting the miR-1252-5p/STAT1.
Hsa_circ_0125356 promotes gemcitabine resistance by modulating WNT canonical and non-canonical pathways via miR-582-5p/FGF9 axis in non-small cell lung cancer.
sdRNA-D43 derived from small nucleolar RNA snoRD43 improves chondrocyte senescence and osteoarthritis progression by negatively regulating PINK1/Parkin-mediated mitophagy pathway via dual-targeting NRF1 and WIPI2.
Unraveling the miR-144-3p/PUMA pathway: a novel regulator of FDX1-mediated cuproptosis in colorectal cancer.
circ-EGFR is a predictor of response to Cetuximab and a potential target in colorectal cancer.
Knockdown of LncRNA PART1 Inhibits Nerve Injury Caused by Ischemic Stroke by Regulating the Expression of miR-638.
The novel circular RNA circG6pc attenuates oxidative stress and mitochondrial damage through miR-7018-5p/Aldh6a1 axis in kidney fibrosis.
Identification of the LncRNA PRNCR1/miR-642a-5p/SSTR3 CeRNA network and its diagnostic value in type 2 diabetes mellitus.
A novel super-enhancer-driven lncRNA LINC00973 governs head and neck squamous cell carcinoma progression through EN2.
Targeted Delivery of AGO-2 to Myocardial Mitochondria via Functionalized Nanoparticles Attenuates Oxidative Stress in Diabetic Cardiomyopathy.
The miR-302 cluster-IRFs-IRF1AS axis regulates influenza A virus replication in a species-specific manner.
Isoliquiritigenin reduces brain metastasis by circNAV3-ST6GALNAC5-EGFR axis in triple-negative breast cancer.
Arenobufagin Induces Ferroptosis in Glioblastoma Cells via Modulating the MiR-149-5p/AEBP1 Axis.
AGO2 mediates immunotherapy failure via suppressing tumor IFN-gamma response-dependent CD8(+) T cell immunity.
CircPRMT5 promotes progression of osteosarcoma by recruiting CNBP to regulate the translation and stability of CDK6 mRNA.
Argonaute-2 autoantibodies: a promising biomarker for predicting mortality in HBV-related acute-on-chronic liver failure patients with cirrhosis.
Circular RNA HMGCS1 sponges MIR4521 to aggravate type 2 diabetes-induced vascular endothelial dysfunction.
LncRNA MIAT suppresses inflammation in LPS-induced J774A.1 macrophages by promoting autophagy through miR-30a-5p/SOCS1 axi.
CircSFMBT2 Plays an Oncogenic Role in Lung Adenocarcinoma Depending on the miR-1305/SALL4 Axis.
miPEP31 alleviates sepsis development by regulating Chi3l1-dependent macrophage polarization.
tRNA-derived RNA fragment, tRF-18-8R6546D2, promotes pancreatic adenocarcinoma progression by directly targeting ASCL2.
Exosomal lncRNA Mir100hg derived from cancer stem cells enhance glycolysis and promote metastasis of melanoma through miR-16-5p and miR-23a-3p.
Circ_0001671 regulates prostate cancer progression through miR-27b-3p/BLM axis.
circPVT1 promotes silica-induced epithelial-mesenchymal transition by modulating the miR-497-5p/TCF3 axis.
miR615-3p inhibited FBLN1 and osteogenic differentiation of umbilical cord mesenchymal stem cells by associated with YTHDF2 in a m(6)A-miRNA interaction manner.
CircUGGT2 downregulation by METTL14-dependent m(6)A modification suppresses gastric cancer progression and cisplatin resistance through interaction with miR-186-3p/MAP3K9 axis.
Cisplatin-based miRNA delivery strategy inspired by the circCPNE1/miR-330-3p pathway for oral squamous cell carcinoma.
Circular RNA circLIFR suppresses papillary thyroid cancer progression by modulating the miR-429/TIMP2 axis.
Circular RNA circMYLK4 shifts energy metabolism from glycolysis to OXPHOS by binding to the calcium channel auxiliary subunit CACNA2D2.
LSM14B coordinates protein component expression in the P-body and controls oocyte maturation.
Hsa_circ_0020134 promotes liver metastasis of colorectal cancer through the miR-183-5p-PFN2-TGF-β/Smad axis.
Hsa_circ_0050900 affects ferroptosis in intrahepatic cholangiocarcinoma cells by targeting hsa‑miR-605‑3p to regulate SLC3A2.
Long non-coding RNA small nucleolar RNA host gene 29 drives chronic myeloid leukemia progression via microRNA-483-3p/Casitas B-lineage Lymphoma axis-mediated activation of the phosphoinositide 3-kinase/Akt pathway.
An essential role for the RNA helicase DDX6 in NMDA receptor-dependent gene silencing and dendritic spine shrinkage.
LncRNA SNHG5 adversely governs follicular growth in PCOS via miR-92a-3p/CDKN1C axis.
lncRNA WAC-AS1 promotes the progression of gastric cancer through miR-204-5p/HOXC8 axis.
CircHIPK3 regulates cementoblast differentiation via the miR-10b-5p/DOHH/NF-κB axis.
RNA-binding protein HNRNPD promotes chondrocyte senescence and osteoarthritis progression through upregulating FOXM1.
METTL3-mediated m(6)A modification of circGLIS3 promotes prostate cancer progression and represents a potential target for ARSI therapy.
Extracellular Vesicles Containing circMYBL1 Induce CD44 in Adenoid Cystic Carcinoma Cells and Pulmonary Endothelial Cells to Promote Lung Metastasis.
LINC00668 promoted non-small lung cancer progression by miR-518c-3p/TRIP4 axis.
Upregulated LncRNA H19 Sponges MiR-106a-5p and Contributes to Aldosterone-Induced Vascular Calcification via Activating the Runx2-Dependent Pathway.
Lnc‑RGS5 sponges miR‑542‑5p to promote FoxM1/VEGFA signaling and breast cancer cell proliferation.
CircABPD1 alleviates oxidative lung injury of bronchopulmonary dysplasia through regulating miR-330-3p/HIF1α axis.
Circ_0001589/miR-1248/HMGB1 axis enhances EMT-mediated metastasis and cisplatin resistance in cervical cancer.
A novel feedback regulated loop of circRRM2-IGF2BP1-MYC promotes breast cancer metastasis.
Exosomal MFI2-AS1 sponge miR-107 promotes non-small cell lung cancer progression through NFAT5.
ELF1 suppresses autophagy to reduce cisplatin resistance via the miR-152-3p/NCAM1/ERK axis in lung cancer cells.
The regulatory role and mechanism of lncTUG1 on cartilage apoptosis and inflammation in osteoarthritis.
LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway.
LncRNA BC promotes lung adenocarcinoma progression by modulating IMPAD1 alternative splicing.
LncRNA PEG11as aggravates cerebral ischemia/reperfusion injury after ischemic stroke through miR-342-5p/PFN1 axis.
CircZBTB46 Protects Acute Myeloid Leukemia Cells from Ferroptotic Cell Death by Upregulating SCD.
saKLK1-374 is more difficult to induce KLK1 expression in normal prostate cell lines than that in prostate cancer cell lines: Rethinking the universality of RNA activation.
LncRNA MIR200CHG inhibits EMT in gastric cancer by stabilizing miR-200c from target-directed miRNA degradation.
A novel circular RNA, circMAML3, promotes tumor progression of prostate cancer by regulating miR-665/MAPK8IP2 axis.
Circ_0000235 targets MCT4 to promote glycolysis and progression of bladder cancer by sponging miR-330-5p.
A 5`-tRNA Derived Fragment NamedtiRNA-Val-CAC-001 Works as a Suppressor in Gastric Cancer.
Tumor promoting effect of circ_002172 associates with induced immune escape in breast cancer via the miR-296-5p/CXCL12 axis.
Evaluation of Early Biomarkers of Atherosclerosis Associated with Polychlorinated Biphenyl Exposure: An in Vitro and in Vivo Study.
Long Noncoding RNA lncNDEPD1 Regulates PD-1 Expression via miR-3619-5p in CD8(+) T Cells.
New Insights into Mitochondrial-Nuclear Interactions Revealed through Analysis of Small RNAs.
Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.
Zhou H, Ji Z, Sun H, Zhang W, Huang Y, Jin G, Cai H, Huang X, Dai J, Zhao J, Chen H, Fan S, Wu Y, Shen J
International journal of biological sciences 2026;22(1):346-364
International journal of biological sciences 2026;22(1):346-364
tRF-Ser-TGA-011 impedes gastric cancer progression by targeting the MAP3K13/JNK signaling cascade.
Ma Y, Lu H, Zhang L, Zhang Y, Shen J, Xu W, Zhang Y, Yan F
Cellular signalling 2026 Mar;139:112323
Cellular signalling 2026 Mar;139:112323
Scutellarin mediates cell cycle arrest and apoptosis in liver cancer through a novel circSRBD1/miR-2682-5p/ESR1 ceRNA axis.
Li Z, Ling Y, Xiao W, Li J, Rong J, Zhang Z, Wei Y, Huo Z, Li D
Journal of translational medicine 2026 Mar 4;24(1)
Journal of translational medicine 2026 Mar 4;24(1)
The circTIMP2/miR-106a/TIMP2 tumor-suppressive axis versus tumor-derived exosomal counteraction in gastric cancer.
Zhu M, Dong X, Zhang N, Huang N, Zhu Z, Ma J
Apoptosis : an international journal on programmed cell death 2026 Mar 19;31(3)
Apoptosis : an international journal on programmed cell death 2026 Mar 19;31(3)
Diagnostic Value of miR-1225-5p in Acute Coronary Syndrome and its Mechanism in ox-LDL Induced Human Coronary Artery Endothelial Cells Injury.
Ju H, Si P, Li S, Yang D
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2026 Jan-Dec;32:10760296251414428
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2026 Jan-Dec;32:10760296251414428
EIF4A3/circPTGR1/miR-4725-5p positive- feedback loop promotes colorectal cancer progression via FAK/AKT signaling pathway.
Dong Y, Ding YH, Yang X, Song XH, Lei XT, Tang YN, Zhang XE, Huang WC, Zhang K, Chen JS
Molecular cancer 2026 Jan 5;25(1):28
Molecular cancer 2026 Jan 5;25(1):28
miR-432 Exacerbates Obesity-Induced Dysregulation of Glucose and Lipid Homeostasis.
Wang C, Hou Y, Zhang M, Wang J, Chu X, Liang M, Sun C, Xie J, Zhang J, Wang CY
Diabetes 2026 Jan 1;75(1):22-36
Diabetes 2026 Jan 1;75(1):22-36
Circular RNA circSCMH1 regulates glycolysis to inhibit gastric cancer metastasis via miR-296-3p/HSPB7-GLUT3 axis.
Yang Y, Wang Q, Gong Z, Chen J, Yang Y, Zhao L, Zhai Y, Zhao T, Du W, Zhang J, Guo W
Translational oncology 2026 Feb;64:102644
Translational oncology 2026 Feb;64:102644
Pelargonidin-3-O-Glucoside Restores Nitric Oxide Production via Interaction with circHMGCS1 to Ameliorate Endothelial Dysfunction.
Zhang M, Du G, Xu Y, Xie L, Chen W
Journal of agricultural and food chemistry 2026 Feb 25;74(7):6180-6192
Journal of agricultural and food chemistry 2026 Feb 25;74(7):6180-6192
RP13-516M14.1 Regulates Autophagy Through miR-429 via Both a ceRNA Network and Direct Interaction.
Yang Z, Zeng A, Yu B, Xie C, Zhu W, Liu H, Gu C, Fu M
Biochemical genetics 2026 Apr;64(2):2416-2447
Biochemical genetics 2026 Apr;64(2):2416-2447
CircASH1L inhibits ferroptosis and enhances cisplatin resistance by sponging miR-515-5p to regulate cell cycle-related CDCA7/RRM2 in ovarian cancer cells.
Feng L, Zou X, Tang L, Yuan Y, He T, Su B, Tang Y, Wang J, Liu K, Li J
Frontiers in pharmacology 2025;16:1563869
Frontiers in pharmacology 2025;16:1563869
METTL3-mediated m(6)A methylation of lncRNA PVT1 promotes the progression of oral squamous cell carcinoma via the miR-185-5p/SERPINB4 axis.
Chen C, Li J, Yang B, Kong L, Zhang D, Guo J, Zhou L, Bai G, Zhao H, Meng Z
American journal of cancer research 2025;15(6):2872-2889
American journal of cancer research 2025;15(6):2872-2889
LINC00152 knockdown exerts repressive effects on epithelial-mesenchymal transition in bladder cancer.
Wang G, Han M, Chen F, Liu J, Zhang J
Cytotechnology 2025 Oct;77(5):166
Cytotechnology 2025 Oct;77(5):166
Avian leukosis virus subgroup J evades innate immunity by activating miR-155 to dually target TRAF3 and STAT1.
Zhang X, Zhou D, Zhou J, Liu X, Ding L, Yan T, Shi M, He S, Cheng Z
PLoS pathogens 2025 Oct;21(10):e1013552
PLoS pathogens 2025 Oct;21(10):e1013552
Hsa_circ_0005325 Regulates the Proliferation, Apoptosis, Colony Formation, Migration, and Angiogenesis-Promoting Behavior of Oral Squamous Cell Carcinoma Cells Through the miR-433-3p/HMGA2 Axis.
Lin Z, Fu Y, Mao L, Yan H, Liu W, Tang X
Clinical and experimental dental research 2025 Oct;11(5):e70208
Clinical and experimental dental research 2025 Oct;11(5):e70208
Astragaloside IV Inhibits Lung Injury and Fibrosis Induced by PM2.5 by Targeting RUNX1 Through miR-362-3p.
Tian H, Zhang Y, Li W, Xie G, Wu J, Liu J
Molecular biotechnology 2025 Nov;67(11):4167-4177
Molecular biotechnology 2025 Nov;67(11):4167-4177
Gastric cancer-derived exosomal miR-196a-5p remodels the pre-metastatic niche for peritoneal dissemination.
Zhang Z, Wang M, Gao X, Tai G, Li F, Wang Z
Cellular signalling 2025 Nov;135:112039
Cellular signalling 2025 Nov;135:112039
M2 macrophage-derived exosomes promote cell proliferation, migration and EMT of non-small cell lung cancer by secreting miR-155-5p.
Fang H, Chi X, Wang M, Liu J, Sun M, Zhang J, Zhang W
Molecular and cellular biochemistry 2025 May;480(5):3019-3032
Molecular and cellular biochemistry 2025 May;480(5):3019-3032
HOTAIR, a ferroptosis-related gene, promotes malignant behavior of breast cancer via sponging miR-206.
Wu W, Yao Z, Chen Y, Xu R, Jin C, Li X
Discover oncology 2025 May 29;16(1):948
Discover oncology 2025 May 29;16(1):948
Tie2-expressing monocytes/macrophages promote angiogenesis in chronically ischaemic brain tissue.
Tai C, Ling C, Yang Y, Zhang B, Sun J, Mo N, Sun T, Huang L, Yao C, Wang H, Chen C
Cell & bioscience 2025 May 21;15(1):62
Cell & bioscience 2025 May 21;15(1):62
Inhibition of hsa_circ_0003314 contributes to trophoblast cell migration and invasion and inhibits pyroptosis in preeclampsia.
Zhou Y, Chen Y, Li L, Lin L
Histochemistry and cell biology 2025 May 16;163(1):52
Histochemistry and cell biology 2025 May 16;163(1):52
Long noncoding RNA SNHG5 promotes 5-fluorouracil resistance in colorectal cancer by regulating miR-26b/p-glycoprotein axis.
Wang B, Zhou Q, Cheng CE, Gu YJ, Jiang TW, Qiu JM, Wei GN, Feng YD, Ren LH, Shi RH
World journal of gastrointestinal oncology 2025 May 15;17(5):102417
World journal of gastrointestinal oncology 2025 May 15;17(5):102417
Uncarboxylated osteocalcin induced miR-143-3p targets SP7 and activates PI3K/Akt signaling in TNBC cells to promote invasion and migration.
Du Q, Xu J, Zhang M, Yang J
Translational oncology 2025 Mar;53:102305
Translational oncology 2025 Mar;53:102305
CircFak promotes mechanical force-induced osteogenesis via FAK/AKT phosphorylation.
Wen Z, Wu F, Shi J, Cheng H, Xie S, Liang D, Li J, Lu Y
Journal of dentistry 2025 Mar;154:105602
Journal of dentistry 2025 Mar;154:105602
CircMRP4 orchestrates podocytes injury via the miR-499-5p/RRAGB/mTORC1 axis in diabetic kidney disease.
Deng S, Huang L, Shao Y, Xie Y, Yuan S, Tang L
Cellular signalling 2025 Mar;127:111611
Cellular signalling 2025 Mar;127:111611
Study on the mechanism of hsa_circ_0074763 regulating the miR-3667-3P/ACSL4 axis in liver fibrosis.
Cheng Y, Song T, Yao J, Wang Q, Meng C, Feng F
Scientific reports 2025 Mar 27;15(1):10548
Scientific reports 2025 Mar 27;15(1):10548
Psychological stress-induced ALKBH5 deficiency promotes tumour innervation and pancreatic cancer via extracellular vesicle transfer of RNA.
Chen Z, Zhou Y, Xue C, Zeng L, Deng S, Xu Z, Li M, Zhao H, He X, Liu S, Liu J, Liu S, Zhao S, Zhang S, Peng X, Wu X, Bai R, Zhuang L, Wu S, Zhang J, Lin D, Huang X, Zheng J
Nature cell biology 2025 Jun;27(6):1035-1047
Nature cell biology 2025 Jun;27(6):1035-1047
m6A reader IGF2BP2-stabilized lncRNA LHX1-DT inhibits renal cell carcinoma (RCC) cell proliferation and invasion by sponging miR-590-5p.
Zhu C, Li R, You X, Xu J, Wang J, Dong D, Chen X, Wang K
NPJ precision oncology 2025 Jun 17;9(1):193
NPJ precision oncology 2025 Jun 17;9(1):193
LNP-enclosed NamiRNA inhibits pancreatic cancer proliferation and migration via dual pathways.
Yu C, Fang Z, Xie Q, Wu Z, Huang P, Yu J, Chen R
Journal of nanobiotechnology 2025 Jul 3;23(1):484
Journal of nanobiotechnology 2025 Jul 3;23(1):484
CircYAP1 inhibits osteosarcoma progression through the miR-135b-5p/FRK axis.
Du M, Zhang X, Cong M, Cai C, Zhang Q, Xin H, Yang L, Geng Q, Shang M, Zhang Z, Shen L, Tan S, Han K
iScience 2025 Jul 18;28(7):112858
iScience 2025 Jul 18;28(7):112858
N6-methyladenosine-modified circQKI inhibits prostate cancer docetaxel-sensitivity via miR-188-3p/Beclin-1 pathway.
Zhao T, Li K, Zhang Y, Dong Y, Li Y, Pang M, Wei Y, Yao B, Zhu Q
Life sciences 2025 Jul 1;372:123646
Life sciences 2025 Jul 1;372:123646
Exosome miR-199a-5p modulated vascular remodeling and inflammatory infiltration of Takayasu's arteritis.
Guo S, Li J, Pang S, Li J, Tian X
Arthritis research & therapy 2025 Jan 20;27(1):11
Arthritis research & therapy 2025 Jan 20;27(1):11
Long non-coding RNA MIR4435-2HG modulates pancreatic cancer stem cells and chemosensitivity to gemcitabine by targeting the miR-1252-5p/STAT1.
Xie B, Wu P, Liu H, Yang X, Huang L
Journal of translational medicine 2025 Feb 7;23(1):165
Journal of translational medicine 2025 Feb 7;23(1):165
Hsa_circ_0125356 promotes gemcitabine resistance by modulating WNT canonical and non-canonical pathways via miR-582-5p/FGF9 axis in non-small cell lung cancer.
Du X, Luo W, Li H, Gu Q, Huang P, Wang C, Li N, Liu F, Xia C
Molecular cancer 2025 Feb 27;24(1):59
Molecular cancer 2025 Feb 27;24(1):59
sdRNA-D43 derived from small nucleolar RNA snoRD43 improves chondrocyte senescence and osteoarthritis progression by negatively regulating PINK1/Parkin-mediated mitophagy pathway via dual-targeting NRF1 and WIPI2.
Deng Z, Li C, Hu S, Zhong Y, Li W, Lin Z, Mo X, Li M, Xu D, Long D, Mao G, Kang Y
Cell communication and signaling : CCS 2025 Feb 11;23(1):77
Cell communication and signaling : CCS 2025 Feb 11;23(1):77
Unraveling the miR-144-3p/PUMA pathway: a novel regulator of FDX1-mediated cuproptosis in colorectal cancer.
Jia G, Li J, Jiang M, Liu N, Ding N, Jiang X, Zhang G, Tan X, Kang Y, Zhang L, Wang F, Zhang Y
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):1693-1710
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):1693-1710
circ-EGFR is a predictor of response to Cetuximab and a potential target in colorectal cancer.
Sui S, Li Y, Maurel J, Goel A
EMBO molecular medicine 2025 Dec;17(12):3525-3554
EMBO molecular medicine 2025 Dec;17(12):3525-3554
Knockdown of LncRNA PART1 Inhibits Nerve Injury Caused by Ischemic Stroke by Regulating the Expression of miR-638.
Xu G, Li H, Huang T, Xu L, Liu D, Ji B
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2025 Dec;133(12):e70096
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2025 Dec;133(12):e70096
The novel circular RNA circG6pc attenuates oxidative stress and mitochondrial damage through miR-7018-5p/Aldh6a1 axis in kidney fibrosis.
Zhao X, Xiong Y, Qin X, Hu J, Huang S, Ni X, Jian J, Yang S, Weng X, Chen H, Chen Z, Liu X, Wang L
Cellular & molecular biology letters 2025 Dec 5;30(1):144
Cellular & molecular biology letters 2025 Dec 5;30(1):144
Identification of the LncRNA PRNCR1/miR-642a-5p/SSTR3 CeRNA network and its diagnostic value in type 2 diabetes mellitus.
Chen J, Long S, Li W, Wang K, Han J, Chen G
Diabetology & metabolic syndrome 2025 Dec 27;18(1):39
Diabetology & metabolic syndrome 2025 Dec 27;18(1):39
A novel super-enhancer-driven lncRNA LINC00973 governs head and neck squamous cell carcinoma progression through EN2.
Wang A, Diao P, Xiao N, Wei Y, Wu Y, Wang Y, Wang X, Yan E, Jiang H, Li J, Cheng J
Cell death & disease 2025 Dec 19;17(1):111
Cell death & disease 2025 Dec 19;17(1):111
Targeted Delivery of AGO-2 to Myocardial Mitochondria via Functionalized Nanoparticles Attenuates Oxidative Stress in Diabetic Cardiomyopathy.
Du W, Jiang Y, Wu L, Liang Y, Wu YP, Liu H, Chen TW
ACS applied materials & interfaces 2025 Dec 10;17(49):66298-66312
ACS applied materials & interfaces 2025 Dec 10;17(49):66298-66312
The miR-302 cluster-IRFs-IRF1AS axis regulates influenza A virus replication in a species-specific manner.
Zhao L, Hou C, Hu X, Jiang C, Li S, Xia J, Ping J
mBio 2025 Aug 13;16(8):e0137525
mBio 2025 Aug 13;16(8):e0137525
Isoliquiritigenin reduces brain metastasis by circNAV3-ST6GALNAC5-EGFR axis in triple-negative breast cancer.
Xie Y, Xie J, Huang G, Zhang J, Song C, Luo Y, Tang H, Tang Y, Xiao X, Zhang C, Shuang Z, Li X
Cancer letters 2025 Aug 1;624:217734
Cancer letters 2025 Aug 1;624:217734
Arenobufagin Induces Ferroptosis in Glioblastoma Cells via Modulating the MiR-149-5p/AEBP1 Axis.
Hu R, Tang S, Xiang Y, Qin S
Journal of applied toxicology : JAT 2025 Apr;45(4):606-619
Journal of applied toxicology : JAT 2025 Apr;45(4):606-619
AGO2 mediates immunotherapy failure via suppressing tumor IFN-gamma response-dependent CD8(+) T cell immunity.
Wang Y, Chen Z, Liang K, Wang W, Hu Z, Mao Y, Liang X, Jiang L, Liu Z, Ma Z
Cell reports 2025 Apr 22;44(4):115445
Cell reports 2025 Apr 22;44(4):115445
CircPRMT5 promotes progression of osteosarcoma by recruiting CNBP to regulate the translation and stability of CDK6 mRNA.
Liu Y, Jiang H, Hu K, Zou H, Zhang W, Liu J, Jian X
PloS one 2024;19(4):e0298947
PloS one 2024;19(4):e0298947
Argonaute-2 autoantibodies: a promising biomarker for predicting mortality in HBV-related acute-on-chronic liver failure patients with cirrhosis.
Wang Y, Hu Y, Li J, Ma H, Shi Z, Wen C, Long Y, Li Z, Sun H, Yang Y, Shi X
Frontiers in cellular and infection microbiology 2024;14:1407064
Frontiers in cellular and infection microbiology 2024;14:1407064
Circular RNA HMGCS1 sponges MIR4521 to aggravate type 2 diabetes-induced vascular endothelial dysfunction.
Zhang M, Du G, Xie L, Xu Y, Chen W
eLife 2024 Sep 5;13
eLife 2024 Sep 5;13
LncRNA MIAT suppresses inflammation in LPS-induced J774A.1 macrophages by promoting autophagy through miR-30a-5p/SOCS1 axi.
Sun L, Yang K, Wang L, Wu S, Wen D, Wang J
Scientific reports 2024 Sep 30;14(1):22608
Scientific reports 2024 Sep 30;14(1):22608
CircSFMBT2 Plays an Oncogenic Role in Lung Adenocarcinoma Depending on the miR-1305/SALL4 Axis.
Zhao X, Xing X, Wu Y
Biochemical genetics 2024 Oct;62(5):3485-3503
Biochemical genetics 2024 Oct;62(5):3485-3503
miPEP31 alleviates sepsis development by regulating Chi3l1-dependent macrophage polarization.
Zhou Y, Yuan Y, Yao X, Wang L, Yao L, Tang D, Chen F, Li J
Biology direct 2024 Nov 18;19(1):117
Biology direct 2024 Nov 18;19(1):117
tRNA-derived RNA fragment, tRF-18-8R6546D2, promotes pancreatic adenocarcinoma progression by directly targeting ASCL2.
Lan S, Liu S, Wang K, Chen W, Zheng D, Zhuang Y, Zhang S
Gene 2024 Nov 15;927:148739
Gene 2024 Nov 15;927:148739
Exosomal lncRNA Mir100hg derived from cancer stem cells enhance glycolysis and promote metastasis of melanoma through miR-16-5p and miR-23a-3p.
Tan J, Tang Y, Li B, Shi L, Zhang Y, Chen Y, Chen Y, Li J, Xiang M, Zhou Y, Xing HR, Wang J
Experimental cell research 2024 Nov 1;443(1):114319
Experimental cell research 2024 Nov 1;443(1):114319
Circ_0001671 regulates prostate cancer progression through miR-27b-3p/BLM axis.
Yang L, Ruan Y, Chen B, Zhu Y, Xu H
Scientific reports 2024 May 28;14(1):12181
Scientific reports 2024 May 28;14(1):12181
circPVT1 promotes silica-induced epithelial-mesenchymal transition by modulating the miR-497-5p/TCF3 axis.
Zhou S, Li Y, Sun W, Ma D, Liu Y, Cheng D, Li G, Ni C
Journal of biomedical research 2024 Mar 26;38(2):163-174
Journal of biomedical research 2024 Mar 26;38(2):163-174
miR615-3p inhibited FBLN1 and osteogenic differentiation of umbilical cord mesenchymal stem cells by associated with YTHDF2 in a m(6)A-miRNA interaction manner.
Yang H, Wang W, Liu H, Zhang C, Cao Y, Long L, Han X, Wang Y, Yan F, Li G, Zhu M, Jin L, Fan Z
Cell proliferation 2024 Jun;57(6):e13607
Cell proliferation 2024 Jun;57(6):e13607
CircUGGT2 downregulation by METTL14-dependent m(6)A modification suppresses gastric cancer progression and cisplatin resistance through interaction with miR-186-3p/MAP3K9 axis.
Chen XY, Yang YL, Yu Y, Chen ZY, Fan HN, Zhang J, Zhu JS
Pharmacological research 2024 Jun;204:107206
Pharmacological research 2024 Jun;204:107206
Cisplatin-based miRNA delivery strategy inspired by the circCPNE1/miR-330-3p pathway for oral squamous cell carcinoma.
Fan HY, Zhao MD, Jiang HJ, Yu ZW, Fan YJ, Liang XH, Tang YL, Sun Y
Acta pharmaceutica Sinica. B 2024 Jun;14(6):2748-2760
Acta pharmaceutica Sinica. B 2024 Jun;14(6):2748-2760
Circular RNA circLIFR suppresses papillary thyroid cancer progression by modulating the miR-429/TIMP2 axis.
Zhang F, Li J, Xu J, Jiang X, Chen S, Nasser QA
Journal of cancer research and clinical oncology 2024 Jun 25;150(6):323
Journal of cancer research and clinical oncology 2024 Jun 25;150(6):323
Circular RNA circMYLK4 shifts energy metabolism from glycolysis to OXPHOS by binding to the calcium channel auxiliary subunit CACNA2D2.
Cao H, Li C, Sun X, Yang J, Li X, Yang G, Jin J, Shi X
The Journal of biological chemistry 2024 Jul;300(7):107426
The Journal of biological chemistry 2024 Jul;300(7):107426
LSM14B coordinates protein component expression in the P-body and controls oocyte maturation.
Zhang H, Zhang T, Wan X, Chen C, Wang S, Qin D, Li L, Yu L, Wu X
Journal of genetics and genomics = Yi chuan xue bao 2024 Jan;51(1):48-60
Journal of genetics and genomics = Yi chuan xue bao 2024 Jan;51(1):48-60
Hsa_circ_0020134 promotes liver metastasis of colorectal cancer through the miR-183-5p-PFN2-TGF-β/Smad axis.
Yu JH, Tan JN, Zhong GY, Zhong L, Hou D, Ma S, Wang PL, Zhang ZH, Lu XQ, Yang B, Zhou SN, Han FH
Translational oncology 2024 Jan;39:101823
Translational oncology 2024 Jan;39:101823
Hsa_circ_0050900 affects ferroptosis in intrahepatic cholangiocarcinoma cells by targeting hsa‑miR-605‑3p to regulate SLC3A2.
Shi X, Yang J, Wang M, Xia L, Zhang L, Qiao S
Oncology letters 2024 Jan;27(1):2
Oncology letters 2024 Jan;27(1):2
Long non-coding RNA small nucleolar RNA host gene 29 drives chronic myeloid leukemia progression via microRNA-483-3p/Casitas B-lineage Lymphoma axis-mediated activation of the phosphoinositide 3-kinase/Akt pathway.
Feng X, Yang L, Liu X, Liu M, Liu L, Liu J, Luo J
Medical oncology (Northwood, London, England) 2024 Jan 22;41(2):60
Medical oncology (Northwood, London, England) 2024 Jan 22;41(2):60
An essential role for the RNA helicase DDX6 in NMDA receptor-dependent gene silencing and dendritic spine shrinkage.
Perooli FM, Wilkinson KA, Pring K, Hanley JG
Scientific reports 2024 Feb 6;14(1):3066
Scientific reports 2024 Feb 6;14(1):3066
LncRNA SNHG5 adversely governs follicular growth in PCOS via miR-92a-3p/CDKN1C axis.
Yang Z, Pan J, Zhou C, Yu C, Zhou Z, Ding G, Liu X, Sheng J, Jin L, Huang H
iScience 2024 Feb 16;27(2):108522
iScience 2024 Feb 16;27(2):108522
lncRNA WAC-AS1 promotes the progression of gastric cancer through miR-204-5p/HOXC8 axis.
Liu Y, Li K, Gao Y, Feng Y, Zhao X, Hou R
Translational oncology 2024 Dec;50:102139
Translational oncology 2024 Dec;50:102139
CircHIPK3 regulates cementoblast differentiation via the miR-10b-5p/DOHH/NF-κB axis.
Zhang G, Tao Z, Li B, Zhu J, Mo L, Cao Z, Du M, He H
Cellular signalling 2024 Dec;124:111427
Cellular signalling 2024 Dec;124:111427
RNA-binding protein HNRNPD promotes chondrocyte senescence and osteoarthritis progression through upregulating FOXM1.
Jiang H, Zhang Y, Hu G, Ji P, Ming J, Li Y, Zhou Y
Communications biology 2024 Dec 24;7(1):1695
Communications biology 2024 Dec 24;7(1):1695
METTL3-mediated m(6)A modification of circGLIS3 promotes prostate cancer progression and represents a potential target for ARSI therapy.
Cheng X, Yang H, Chen Y, Zeng Z, Liu Y, Zhou X, Zhang C, Xie A, Wang G
Cellular & molecular biology letters 2024 Aug 14;29(1):109
Cellular & molecular biology letters 2024 Aug 14;29(1):109
Extracellular Vesicles Containing circMYBL1 Induce CD44 in Adenoid Cystic Carcinoma Cells and Pulmonary Endothelial Cells to Promote Lung Metastasis.
Fu M, Gao Q, Xiao M, Li RF, Sun XY, Li SL, Peng X, Ge XY
Cancer research 2024 Aug 1;84(15):2484-2500
Cancer research 2024 Aug 1;84(15):2484-2500
LINC00668 promoted non-small lung cancer progression by miR-518c-3p/TRIP4 axis.
Lu Z, Xiao Z, Wang Q, Pan C, Xia Y, Wu W, Chen L
Cancer biomarkers : section A of Disease markers 2023;38(3):379-391
Cancer biomarkers : section A of Disease markers 2023;38(3):379-391
Upregulated LncRNA H19 Sponges MiR-106a-5p and Contributes to Aldosterone-Induced Vascular Calcification via Activating the Runx2-Dependent Pathway.
Li XZ, Xiong ZC, Zhang SL, Hao QY, Liu ZY, Zhang HF, Wang JF, Gao JW, Liu PM
Arteriosclerosis, thrombosis, and vascular biology 2023 Sep;43(9):1684-1699
Arteriosclerosis, thrombosis, and vascular biology 2023 Sep;43(9):1684-1699
Lnc‑RGS5 sponges miR‑542‑5p to promote FoxM1/VEGFA signaling and breast cancer cell proliferation.
Song J, Tang Y, Song F
International journal of oncology 2023 Oct;63(4)
International journal of oncology 2023 Oct;63(4)
CircABPD1 alleviates oxidative lung injury of bronchopulmonary dysplasia through regulating miR-330-3p/HIF1α axis.
Li H, Ma K, Dou H, Liu L, Qian Y, Li S, Chen J, Han S, Gu X, Yin J
The international journal of biochemistry & cell biology 2023 Oct;163:106464
The international journal of biochemistry & cell biology 2023 Oct;163:106464
Circ_0001589/miR-1248/HMGB1 axis enhances EMT-mediated metastasis and cisplatin resistance in cervical cancer.
Ma T, Guo J, Han J, Li L, Ren Y, Huang J, Diao G, Zheng X, Zheng Y
Molecular carcinogenesis 2023 Nov;62(11):1645-1658
Molecular carcinogenesis 2023 Nov;62(11):1645-1658
A novel feedback regulated loop of circRRM2-IGF2BP1-MYC promotes breast cancer metastasis.
Hao R, Zhang L, Si Y, Zhang P, Wang Y, Li B, Hu J, Qi Y
Cancer cell international 2023 Mar 25;23(1):54
Cancer cell international 2023 Mar 25;23(1):54
Exosomal MFI2-AS1 sponge miR-107 promotes non-small cell lung cancer progression through NFAT5.
Xu J, Wang H, Shi B, Li N, Xu G, Yan X, Xu L
Cancer cell international 2023 Mar 18;23(1):51
Cancer cell international 2023 Mar 18;23(1):51
ELF1 suppresses autophagy to reduce cisplatin resistance via the miR-152-3p/NCAM1/ERK axis in lung cancer cells.
Zhao L, Wu X, Zhang Z, Fang L, Yang B, Li Y
Cancer science 2023 Jun;114(6):2650-2663
Cancer science 2023 Jun;114(6):2650-2663
The regulatory role and mechanism of lncTUG1 on cartilage apoptosis and inflammation in osteoarthritis.
Liu NN, Huang YP, Shao YB, Fan XF, Sun HY, Wang TR, Yao T, Chen XY
Arthritis research & therapy 2023 Jun 20;25(1):106
Arthritis research & therapy 2023 Jun 20;25(1):106
LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway.
Wu H, Li A, Zheng Q, Gu J, Zhou W
Cancer cell international 2023 Jul 4;23(1):130
Cancer cell international 2023 Jul 4;23(1):130
LncRNA BC promotes lung adenocarcinoma progression by modulating IMPAD1 alternative splicing.
Chen QW, Cai QQ, Yang Y, Dong S, Liu YY, Chen ZY, Kang CL, Qi B, Dong YW, Wu W, Zhuang LP, Shen YH, Meng ZQ, Wu XZ
Clinical and translational medicine 2023 Jan;13(1):e1129
Clinical and translational medicine 2023 Jan;13(1):e1129
LncRNA PEG11as aggravates cerebral ischemia/reperfusion injury after ischemic stroke through miR-342-5p/PFN1 axis.
Yu Z, Zhu M, Shu D, Zhang R, Xiang Z, Jiang A, Liu S, Zhang C, Yuan Q, Hu X
Life sciences 2023 Jan 15;313:121276
Life sciences 2023 Jan 15;313:121276
CircZBTB46 Protects Acute Myeloid Leukemia Cells from Ferroptotic Cell Death by Upregulating SCD.
Long F, Lin Z, Long Q, Lu Z, Zhu K, Zhao M, Yang M
Cancers 2023 Jan 11;15(2)
Cancers 2023 Jan 11;15(2)
saKLK1-374 is more difficult to induce KLK1 expression in normal prostate cell lines than that in prostate cancer cell lines: Rethinking the universality of RNA activation.
Zhang M, Lin D, Luo C, Wei P, Cui K, Chen K, Chen Z
Biochemical and biophysical research communications 2023 Feb 5;643:157-168
Biochemical and biophysical research communications 2023 Feb 5;643:157-168
LncRNA MIR200CHG inhibits EMT in gastric cancer by stabilizing miR-200c from target-directed miRNA degradation.
Zhu Y, Huang C, Zhang C, Zhou Y, Zhao E, Zhang Y, Pan X, Huang H, Liao W, Wang X
Nature communications 2023 Dec 8;14(1):8141
Nature communications 2023 Dec 8;14(1):8141
A novel circular RNA, circMAML3, promotes tumor progression of prostate cancer by regulating miR-665/MAPK8IP2 axis.
Zhenhao Z, Ru C, Xiaofeng C, Heng Y, Gongxian W
Cell death discovery 2023 Dec 14;9(1):455
Cell death discovery 2023 Dec 14;9(1):455
Circ_0000235 targets MCT4 to promote glycolysis and progression of bladder cancer by sponging miR-330-5p.
Zhong J, Xu A, Xu P, Su M, Wang P, Liu Z, Li B, Liu C, Jiang N
Cell death discovery 2023 Aug 2;9(1):283
Cell death discovery 2023 Aug 2;9(1):283
A 5`-tRNA Derived Fragment NamedtiRNA-Val-CAC-001 Works as a Suppressor in Gastric Cancer.
Zheng J, Li C, Zhu Z, Yang F, Wang X, Jiang P, Yan F
Cancer management and research 2022;14:2323-2337
Cancer management and research 2022;14:2323-2337
Tumor promoting effect of circ_002172 associates with induced immune escape in breast cancer via the miR-296-5p/CXCL12 axis.
Li P, Ren X, Zheng Y, Sun J, Ye G
International immunopharmacology 2022 May;106:108530
International immunopharmacology 2022 May;106:108530
Evaluation of Early Biomarkers of Atherosclerosis Associated with Polychlorinated Biphenyl Exposure: An in Vitro and in Vivo Study.
Yang B, Ye Z, Wang Y, Guo H, Lehmler HJ, Huang R, Song E, Song Y
Environmental health perspectives 2022 Mar;130(3):37011
Environmental health perspectives 2022 Mar;130(3):37011
Long Noncoding RNA lncNDEPD1 Regulates PD-1 Expression via miR-3619-5p in CD8(+) T Cells.
Cheng S, Li F, Qin H, Ping Y, Zhao Q, Gao Q, Song M, Qu J, Shan J, Zhang K, Zhang Z, Lian J, Liu S, Wang L, Zhang Y
Journal of immunology (Baltimore, Md. : 1950) 2022 Mar 15;208(6):1483-1492
Journal of immunology (Baltimore, Md. : 1950) 2022 Mar 15;208(6):1483-1492
New Insights into Mitochondrial-Nuclear Interactions Revealed through Analysis of Small RNAs.
Pozzi A, Dowling DK
Genome biology and evolution 2022 Feb 4;14(2)
Genome biology and evolution 2022 Feb 4;14(2)
Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.
Peng T, He Y, Wang T, Yu J, Ma X, Zhou Z, Sheng Y, Li L, Peng H, Li S, Zou J, Yuan Y, Zhao Y, Shi H, Li F, Liu W, Hu K, Lu X, Zhang G, Wang F
Journal of medicinal chemistry 2022 Aug 25;65(16):11010-11033
Journal of medicinal chemistry 2022 Aug 25;65(16):11010-11033
No comments: Submit comment
No validations: Submit validation data