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- Antibody Data
- Antigen structure
- References [15]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 14630-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14630-1-AP, RRID:AB_2301203
- Product name
- RMI1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RMI1 antibody (Cat. #14630-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The SMC5/SMC6 complex is critical for resolving R-loop-induced transcription-replication conflicts.
Rational design of synthetic proteins using a genome-scale CRISPR screen.
High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer.
Potent Cyclic Peptide Inhibitors Disrupt the FANCM-RMI Interaction.
Topoisomerase IIIα controls alternative lengthening of telomeres.
Identifying key palmitoylation-associated genes in endometriosis through genomic data analysis.
RMI1 facilitates repair of ionizing radiation-induced DNA damage and maintenance of genomic stability.
Hsa_circ_0091581 promotes glioma progression by regulating RMI1 via sponging miR-1243-5p.
Improved Genome Editing through Inhibition of FANCM and Members of the BTR Dissolvase Complex.
Identification and Bioinformatic Assessment of circRNA Expression After RMI1 Knockdown and Ionizing Radiation Exposure.
Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA.
Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia.
Knockdown of RMI1 impairs DNA repair under DNA replication stress.
Accumulation and Phosphorylation of RecQ-Mediated Genome Instability Protein 1 (RMI1) at Serine 284 and Serine 292 during Mitosis.
DNA2 cooperates with the WRN and BLM RecQ helicases to mediate long-range DNA end resection in human cells.
Wu T, Li Y, Zhao Y, Bournique E, Ortega P, Nie M, Wang Y, Wang H, Buisson R, Hickson ID, Boddy MN, Wu X
Nucleic acids research 2026 Jan 14;54(2)
Nucleic acids research 2026 Jan 14;54(2)
Rational design of synthetic proteins using a genome-scale CRISPR screen.
Burrell WH, Mueller SJ, Daniloski Z, Doyle PD, Rovsing AB, James C, Drabkin M, Chou CY, So HYA, Katgara L, Sookdeo A, Lu L, Cisse GI, Yan RE, Sanjana NE
bioRxiv : the preprint server for biology 2026 Feb 20;
bioRxiv : the preprint server for biology 2026 Feb 20;
High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer.
Shen P, Wang X, Yan X, Du H, Wu B, Cao X
Oncology reports 2026 Apr;55(4)
Oncology reports 2026 Apr;55(4)
Potent Cyclic Peptide Inhibitors Disrupt the FANCM-RMI Interaction.
Alcock LJ, Gao T, Bythell-Douglas R, Gao J, Krishna Sudhakar H, Huang T, Young R, Vu QN, Deshpande C, Wilkinson-White LE, Passioura T, Pickett HA, Deans AJ, Lau YH
Journal of medicinal chemistry 2025 Jun 26;68(12):12615-12625
Journal of medicinal chemistry 2025 Jun 26;68(12):12615-12625
Topoisomerase IIIα controls alternative lengthening of telomeres.
Khandagale P, Sun Y, Taniyama D, Saha S, Saha LK, Pommier Y
Cell reports 2025 Aug 26;44(8):116066
Cell reports 2025 Aug 26;44(8):116066
Identifying key palmitoylation-associated genes in endometriosis through genomic data analysis.
Kai J, Su J, You Y, Liang X, Huang H, Fang J, Chen Q
BMC women's health 2025 Apr 5;25(1):161
BMC women's health 2025 Apr 5;25(1):161
RMI1 facilitates repair of ionizing radiation-induced DNA damage and maintenance of genomic stability.
Fang L, Sun Y, Dong M, Yang M, Hao J, Li J, Zhang H, He N, Du L, Xu C
Cell death discovery 2023 Nov 25;9(1):426
Cell death discovery 2023 Nov 25;9(1):426
Hsa_circ_0091581 promotes glioma progression by regulating RMI1 via sponging miR-1243-5p.
Qian J, Xu Y, Xu X, Tao Z, Luo Y, Xu Y, Zhang Y, Qian C
Journal of Cancer 2021;12(11):3249-3256
Journal of Cancer 2021;12(11):3249-3256
Improved Genome Editing through Inhibition of FANCM and Members of the BTR Dissolvase Complex.
de Alencastro G, Puzzo F, Pavel-Dinu M, Zhang F, Pillay S, Majzoub K, Tiffany M, Jang H, Sheikali A, Cromer MK, Meetei R, Carette JE, Porteus MH, Pekrun K, Kay MA
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Mar 3;29(3):1016-1027
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Mar 3;29(3):1016-1027
Identification and Bioinformatic Assessment of circRNA Expression After RMI1 Knockdown and Ionizing Radiation Exposure.
Sun Y, Fang L, Yang M, He N, Wang J, Zhang M, Ji K, Wang Q, Liu Y, Du L, Wang Y, Xu C, Liu Q
DNA and cell biology 2021 Jan;40(1):80-92
DNA and cell biology 2021 Jan;40(1):80-92
Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA.
Nicholls TJ, Nadalutti CA, Motori E, Sommerville EW, Gorman GS, Basu S, Hoberg E, Turnbull DM, Chinnery PF, Larsson NG, Larsson E, Falkenberg M, Taylor RW, Griffith JD, Gustafsson CM
Molecular cell 2018 Jan 4;69(1):9-23.e6
Molecular cell 2018 Jan 4;69(1):9-23.e6
Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia.
Moder M, Velimezi G, Owusu M, Mazouzi A, Wiedner M, Ferreira da Silva J, Robinson-Garcia L, Schischlik F, Slavkovsky R, Kralovics R, Schuster M, Bock C, Ideker T, Jackson SP, Menche J, Loizou JI
Nature communications 2017 Nov 1;8(1):1238
Nature communications 2017 Nov 1;8(1):1238
Knockdown of RMI1 impairs DNA repair under DNA replication stress.
Xu C, Fang L, Kong Y, Xiao C, Yang M, Du LQ, Liu Q
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):158-164
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):158-164
Accumulation and Phosphorylation of RecQ-Mediated Genome Instability Protein 1 (RMI1) at Serine 284 and Serine 292 during Mitosis.
Xu C, Wang Y, Wang L, Wang Q, Du LQ, Fan S, Liu Q, Li L
International journal of molecular sciences 2015 Nov 4;16(11):26395-405
International journal of molecular sciences 2015 Nov 4;16(11):26395-405
DNA2 cooperates with the WRN and BLM RecQ helicases to mediate long-range DNA end resection in human cells.
Sturzenegger A, Burdova K, Kanagaraj R, Levikova M, Pinto C, Cejka P, Janscak P
The Journal of biological chemistry 2014 Sep 26;289(39):27314-27326
The Journal of biological chemistry 2014 Sep 26;289(39):27314-27326
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 14630-1-AP(RMI1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-RMI1 (IP:14630-1-AP, 3ug; Detection:14630-1-AP 1:1500) with HeLa cells lysate 3800ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 14630-1-AP(RMI1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RMI1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RMI1. This antibody recognizes human,mouse,rat antigen. The RMI1 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
