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- Antigen structure
- References [8]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 14630-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14630-1-AP, RRID:AB_2301203
- Product name
- RMI1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RMI1 antibody (Cat. #14630-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references RMI1 facilitates repair of ionizing radiation-induced DNA damage and maintenance of genomic stability.
Hsa_circ_0091581 promotes glioma progression by regulating RMI1 via sponging miR-1243-5p.
Identification and Bioinformatic Assessment of circRNA Expression After RMI1 Knockdown and Ionizing Radiation Exposure.
Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA.
Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia.
Knockdown of RMI1 impairs DNA repair under DNA replication stress.
Accumulation and Phosphorylation of RecQ-Mediated Genome Instability Protein 1 (RMI1) at Serine 284 and Serine 292 during Mitosis.
DNA2 cooperates with the WRN and BLM RecQ helicases to mediate long-range DNA end resection in human cells.
Fang L, Sun Y, Dong M, Yang M, Hao J, Li J, Zhang H, He N, Du L, Xu C
Cell death discovery 2023 Nov 25;9(1):426
Cell death discovery 2023 Nov 25;9(1):426
Hsa_circ_0091581 promotes glioma progression by regulating RMI1 via sponging miR-1243-5p.
Qian J, Xu Y, Xu X, Tao Z, Luo Y, Xu Y, Zhang Y, Qian C
Journal of Cancer 2021;12(11):3249-3256
Journal of Cancer 2021;12(11):3249-3256
Identification and Bioinformatic Assessment of circRNA Expression After RMI1 Knockdown and Ionizing Radiation Exposure.
Sun Y, Fang L, Yang M, He N, Wang J, Zhang M, Ji K, Wang Q, Liu Y, Du L, Wang Y, Xu C, Liu Q
DNA and cell biology 2021 Jan;40(1):80-92
DNA and cell biology 2021 Jan;40(1):80-92
Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA.
Nicholls TJ, Nadalutti CA, Motori E, Sommerville EW, Gorman GS, Basu S, Hoberg E, Turnbull DM, Chinnery PF, Larsson NG, Larsson E, Falkenberg M, Taylor RW, Griffith JD, Gustafsson CM
Molecular cell 2018 Jan 4;69(1):9-23.e6
Molecular cell 2018 Jan 4;69(1):9-23.e6
Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia.
Moder M, Velimezi G, Owusu M, Mazouzi A, Wiedner M, Ferreira da Silva J, Robinson-Garcia L, Schischlik F, Slavkovsky R, Kralovics R, Schuster M, Bock C, Ideker T, Jackson SP, Menche J, Loizou JI
Nature communications 2017 Nov 1;8(1):1238
Nature communications 2017 Nov 1;8(1):1238
Knockdown of RMI1 impairs DNA repair under DNA replication stress.
Xu C, Fang L, Kong Y, Xiao C, Yang M, Du LQ, Liu Q
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):158-164
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):158-164
Accumulation and Phosphorylation of RecQ-Mediated Genome Instability Protein 1 (RMI1) at Serine 284 and Serine 292 during Mitosis.
Xu C, Wang Y, Wang L, Wang Q, Du LQ, Fan S, Liu Q, Li L
International journal of molecular sciences 2015 Nov 4;16(11):26395-405
International journal of molecular sciences 2015 Nov 4;16(11):26395-405
DNA2 cooperates with the WRN and BLM RecQ helicases to mediate long-range DNA end resection in human cells.
Sturzenegger A, Burdova K, Kanagaraj R, Levikova M, Pinto C, Cejka P, Janscak P
The Journal of biological chemistry 2014 Sep 26;289(39):27314-27326
The Journal of biological chemistry 2014 Sep 26;289(39):27314-27326
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 14630-1-AP(RMI1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-RMI1 (IP:14630-1-AP, 3ug; Detection:14630-1-AP 1:1500) with HeLa cells lysate 3800ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 14630-1-AP(RMI1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RMI1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RMI1. This antibody recognizes human,mouse,rat antigen. The RMI1 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
