Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN350080 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN350080, RRID:AB_10781319
- Product name
- anti-Activity-Regulated Cytoskeleton-Associated Protein (Arc) (Arg3) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from human Arg3.1 (ARC) was used as the antigen. The peptide is homologous in rat and mouse.
- Reactivity
- Human, Mouse, Rat
- Host
- Goat
- Epitope
- Arg3
- Vial size
- 100 μL
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
- Handling
- Avoid freeze and thaw cycles.
Submitted references Tinnitus behavior and hearing function correlate with the reciprocal expression patterns of BDNF and Arg3.1/arc in auditory neurons following acoustic trauma.
Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors.
Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission.
Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking.
Tan J, Rüttiger L, Panford-Walsh R, Singer W, Schulze H, Kilian SB, Hadjab S, Zimmermann U, Köpschall I, Rohbock K, Knipper M
Neuroscience 2007 Mar 16;145(2):715-26
Neuroscience 2007 Mar 16;145(2):715-26
Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors.
Shepherd JD, Rumbaugh G, Wu J, Chowdhury S, Plath N, Kuhl D, Huganir RL, Worley PF
Neuron 2006 Nov 9;52(3):475-84
Neuron 2006 Nov 9;52(3):475-84
Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission.
Rial Verde EM, Lee-Osbourne J, Worley PF, Malinow R, Cline HT
Neuron 2006 Nov 9;52(3):461-74
Neuron 2006 Nov 9;52(3):461-74
Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking.
Chowdhury S, Shepherd JD, Okuno H, Lyford G, Petralia RS, Plath N, Kuhl D, Huganir RL, Worley PF
Neuron 2006 Nov 9;52(3):445-59
Neuron 2006 Nov 9;52(3):445-59
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