BS6149

antibody from Bioworld Technology, Inc
Targeting: SPINK1 PCTT, PSTI, Spink3, TATI
Provider product page for BS6149
Western blot
Immunohistochemistry

Antibody data

Product number
BS6149 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SPINK1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human SPINK1.
Description
This is a trypsin inhibitor, its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT) [MIM:167800]. A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Defects in SPINK1 are the cause of susceptibility to tropical calcific pancreatitis (TCP) [MIM:608189]. TCP is an idiopathic, juvenile, nonalcoholic form of chronic pancreatitis widely prevalent in several tropical countries. It can be associated with fibrocalculous pancreatic diabetes (FCPD) depending on both environmental and genetic factors. TCP differs from alcoholic pancreatitis by a much younger age of onset, pancreatic calcification, a high incidence of insulin dependent but ketosis resistant diabetes mellitus, and an exceptionally high incidence of pancreatic cancer.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SPINK1 protein structure - BS6149 shown in red.