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- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 12541-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12541-1-AP, RRID:AB_10734598
- Product name
- PIP5K1B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PIP5K1B antibody (Cat. #12541-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors.
Phosphatidylinositol 4,5-bisphosphate controls Rab7 and PLEKHM1 membrane cycling during autophagosome-lysosome fusion.
PTPRN2 and PLCĪ²1 promote metastatic breast cancer cell migration through PI(4,5)P2-dependent actin remodeling.
Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation.
Sivakumaren SC, Shim H, Zhang T, Ferguson FM, Lundquist MR, Browne CM, Seo HS, Paddock MN, Manz TD, Jiang B, Hao MF, Krishnan P, Wang DG, Yang TJ, Kwiatkowski NP, Ficarro SB, Cunningham JM, Marto JA, Dhe-Paganon S, Cantley LC, Gray NS
Cell chemical biology 2020 May 21;27(5):525-537.e6
Cell chemical biology 2020 May 21;27(5):525-537.e6
Phosphatidylinositol 4,5-bisphosphate controls Rab7 and PLEKHM1 membrane cycling during autophagosome-lysosome fusion.
Baba T, Toth DJ, Sengupta N, Kim YJ, Balla T
The EMBO journal 2019 Apr 15;38(8):e100312
The EMBO journal 2019 Apr 15;38(8):e100312
PTPRN2 and PLCĪ²1 promote metastatic breast cancer cell migration through PI(4,5)P2-dependent actin remodeling.
Sengelaub CA, Navrazhina K, Ross JB, Halberg N, Tavazoie SF
The EMBO journal 2016 Jan 4;35(1):62-76
The EMBO journal 2016 Jan 4;35(1):62-76
Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation.
Chang J, Lee S, Blackstone C
The Journal of clinical investigation 2014 Dec;124(12):5249-62
The Journal of clinical investigation 2014 Dec;124(12):5249-62
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human testis tissue were subjected to SDS PAGE followed by western blot with 12541-1-AP(PIP5K1B antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung using 12541-1-AP(PIP5K1B antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PIP5K1B antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PIP5K1B. This antibody recognizes human, mouse, rat antigen. The PIP5K1B antibody has been validated for the following applications: ELISA, WB, IHC analysis.
