Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN967741 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Son of Sevenless Homolog 1 (Drosophila) (SOS1) (AA 1-109) antibody
- Antibody type
- Monoclonal
- Antigen
- Mouse mSos1 aa. 1-109
- Description
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Reactivity
- Human, Mouse, Rat, Canine
- Host
- Mouse
- Epitope
- AA 1-109
- Isotype
- IgG
- Antibody clone number
- 25-SOS1
- Vial size
- 150 μg
- Storage
- Store undiluted at -20° C.
Submitted references Light Chain 3 associates with a Sos1 guanine nucleotide exchange factor: its significance in the Sos1-mediated Rac1 signaling leading to membrane ruffling.
Chronic myelogenous leukemia blast cell proliferation is inhibited by peptides that disrupt Grb2-SoS complexes.
ZAP-70 is essential for the T cell antigen receptor-induced plasma membrane targeting of SOS and Vav in T cells.
Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor.
Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation.
Furuta S, Miura K, Copeland T, Shang WH, Oshima A, Kamata T
Oncogene 2002 Oct 10;21(46):7060-6
Oncogene 2002 Oct 10;21(46):7060-6
Chronic myelogenous leukemia blast cell proliferation is inhibited by peptides that disrupt Grb2-SoS complexes.
Kardinal C, Konkol B, Lin H, Eulitz M, Schmidt EK, Estrov Z, Talpaz M, Arlinghaus RB, Feller SM
Blood 2001 Sep 15;98(6):1773-81
Blood 2001 Sep 15;98(6):1773-81
ZAP-70 is essential for the T cell antigen receptor-induced plasma membrane targeting of SOS and Vav in T cells.
Salojin KV, Zhang J, Meagher C, Delovitch TL
The Journal of biological chemistry 2000 Feb 25;275(8):5966-75
The Journal of biological chemistry 2000 Feb 25;275(8):5966-75
Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor.
Buday L, Downward J
Cell 1993 May 7;73(3):611-20
Cell 1993 May 7;73(3):611-20
Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation.
Egan SE, Giddings BW, Brooks MW, Buday L, Sizeland AM, Weinberg RA
Nature 1993 May 6;363(6424):45-51
Nature 1993 May 6;363(6424):45-51
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