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- References [5]
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- Immunocytochemistry [2]
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- Product number
- ABIN238504 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Son of Sevenless Homolog 1 (Drosophila) (SOS1) antibody
- Antibody type
- Monoclonal
- Description
- Protein A affinity chromatography.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- SOS-1
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid freeze/thaw cycles.Shelf life: One year from despatch.
Submitted references A Ras-induced conformational switch in the Ras activator Son of sevenless.
Son of sevenless directly links the Robo receptor to rac activation to control axon repulsion at the midline.
New class of Son-of-sevenless (Sos) alleles highlights the complexities of Sos function.
Mechanisms through which Sos-1 coordinates the activation of Ras and Rac.
Basis for signaling specificity difference between Sos and Ras-GRF guanine nucleotide exchange factors.
Freedman TS, Sondermann H, Friedland GD, Kortemme T, Bar-Sagi D, Marqusee S, Kuriyan J
Proceedings of the National Academy of Sciences of the United States of America 2006 Nov 7;103(45):16692-7
Proceedings of the National Academy of Sciences of the United States of America 2006 Nov 7;103(45):16692-7
Son of sevenless directly links the Robo receptor to rac activation to control axon repulsion at the midline.
Yang L, Bashaw GJ
Neuron 2006 Nov 22;52(4):595-607
Neuron 2006 Nov 22;52(4):595-607
New class of Son-of-sevenless (Sos) alleles highlights the complexities of Sos function.
Silver SJ, Chen F, Doyon L, Zink AW, Rebay I
Genesis (New York, N.Y. : 2000) 2004 Aug;39(4):263-72
Genesis (New York, N.Y. : 2000) 2004 Aug;39(4):263-72
Mechanisms through which Sos-1 coordinates the activation of Ras and Rac.
Innocenti M, Tenca P, Frittoli E, Faretta M, Tocchetti A, Di Fiore PP, Scita G
The Journal of cell biology 2002 Jan 7;156(1):125-36
The Journal of cell biology 2002 Jan 7;156(1):125-36
Basis for signaling specificity difference between Sos and Ras-GRF guanine nucleotide exchange factors.
Tian X, Feig LA
The Journal of biological chemistry 2001 Dec 14;276(50):47248-56
The Journal of biological chemistry 2001 Dec 14;276(50):47248-56
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Image(s): Immunofluorescence
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Image(s): Immunofluorescence
