67605-1-Ig

antibody from Proteintech Group

Targeting: CD63 ME491, MLA1, TSPAN30

Provider product page for 67605-1-Ig

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Product number: 67605-1-Ig - Provider product page
Provider: Proteintech Group
Product name: CD63 antibody
Antibody type: Monoclonal
Description: CD63 antibody (Cat. #67605-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: IF, IHC, WB,ELISA.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 3D4D1
Vial size: 20ul, 150ul

CD63 protein structure - 67605-1-Ig shown in red.

Submitted references NOX2 and NOX4 expression in monocytes and macrophages-extracellular vesicles in signalling and therapeutics.

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CircPRRC2C Promotes the Oncogenic Phenotypes of Laryngeal Squamous Cell Carcinoma Cells via MiR-136-5p/HOXD11 Axis.

Peng X, Chen X, Peng S, Chen Y, Li Y, Tian Y
Molecular biotechnology 2024 Sep;66(9):2381-2395

Exosomal circZNF800 Derived from Glioma Stem-like Cells Regulates Glioblastoma Tumorigenicity via the PIEZO1/Akt Axis.

Zhang N, Wu P, Mu M, Niu C, Hu S
Molecular neurobiology 2024 Sep;61(9):6556-6571

Identification of novel biomarker hsa_circ_0003914 for rheumatoid arthritis from plasma exosomes.

He Q, Sha X, Ji J, Liu W, Sun C, Gu Z
International immunopharmacology 2024 Sep 10;138:112562

Cellulose Nanofibrils of High Immunoaffinity for Efficient Enrichment of Small Extracellular Vesicles.

Wang Z, Dai J, He H, Si T, Ng K, Zheng S, Zhou X, Zhou Z, Yuan H, Yang M
Small methods 2024 Nov;8(11):e2400426

Dexamethasone-Integrated Mesenchymal Stem Cells for Systemic Lupus Erythematosus Treatment via Multiple Immunomodulatory Mechanisms.

Ma W, Che J, Chen W, Wang D, Zhang H, Zhao Y
ACS nano 2024 May 21;18(20):13249-13265

Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression.

Khan F, Lin Y, Ali H, Pang L, Dunterman M, Hsu WH, Frenis K, Grant Rowe R, Wainwright DA, McCortney K, Billingham LK, Miska J, Horbinski C, Lesniak MS, Chen P
Nature communications 2024 Mar 5;15(1):1987

Hypoxia-Challenged Pancreatic Adenocarcinoma Cell-Derived Exosomal circR3HCC1L Drives Tumor Growth Via Upregulating PKM2 Through Sequestering miR-873-5p.

Wang L, Zhou S, Ruan Y, Wu X, Zhang X, Li Y, Ying D, Lu Y, Tian Y, Cheng G, Zhang J, Lv K, Zhou X
Molecular biotechnology 2024 Mar 25;

Exploring the therapeutic potential of Sirt6-enriched adipose stem cell-derived exosomes in myocardial ischemia-reperfusion injury: unfolding new epigenetic frontiers.

Liu K, Wang H, Wang Y, Zhang X, Wang R, Zhang Z, Wang J, Lu X, Wu X, Han Y
Clinical epigenetics 2024 Jan 3;16(1):7

Interorgan communication in neurogenic heterotopic ossification: the role of brain-derived extracellular vesicles.

Lu W, Yan J, Wang C, Qin W, Han X, Qin Z, Wei Y, Xu H, Gao J, Gao C, Ye T, Tay FR, Niu L, Jiao K
Bone research 2024 Feb 22;12(1):11

In-situ gelation of fibrin gel encapsulating platelet-rich plasma-derived exosomes promotes rotator cuff healing.

Li M, Shi L, Chen X, Yi D, Ding Y, Chen J, Xing G, Chen S, Wang L, Zhang Y, Zhu Y, Wang Y
Communications biology 2024 Feb 20;7(1):205

Down-expression of miR-494-3p in senescent osteocyte-derived exosomes inhibits osteogenesis and accelerates age-related bone loss via PTEN/PI3K/AKT pathway.

Yao C, Sun J, Luo W, Chen H, Chen T, Chen C, Zhang B, Zhang Y
Bone & joint research 2024 Feb 1;13(2):52-65

Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.

Jiang Y, Wang Y, Chen G, Sun F, Wu Q, Huang Q, Zeng D, Qiu W, Wang J, Yao Z, Liang B, Li S, Wu J, Huang N, Wang Y, Chen J, Zhai X, Huang L, Xu B, Yamamoto M, Tsukamoto T, Nomura S, Liao W, Shi M
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11

Hepatocyte-derived exosomes deliver the lncRNA CYTOR to hepatic stellate cells and promote liver fibrosis.

Xu W, Mo W, Han D, Dai W, Xu X, Li J, Xu X
Journal of cellular and molecular medicine 2024 Apr;28(8):e18234

Enhancing Skin Injury Repair: Combined Application of PF-127 Hydrogel and hADSC-Exos Containing miR-148a-3p.

Zhang Q, Su P, Zhao F, Ren H, He C, Wu Q, Wang Z, Ma J, Huang X, Wang Z
ACS biomaterials science & engineering 2024 Apr 8;10(4):2235-2250

Knockdown of AK142426 suppresses M2 macrophage polarization and inflammation in peritoneal fibrosis via binding to c-Jun.

Shao Q, Jiang C, Zhang Q, Liu J, Jin B, Zhao M, Xia Y
The journal of gene medicine 2023 Sep;25(9):e3524

Low-temperature 3D-printed collagen/chitosan scaffolds loaded with exosomes derived from neural stem cells pretreated with insulin growth factor-1 enhance neural regeneration after traumatic brain injury.

Liu XY, Feng YH, Feng QB, Zhang JY, Zhong L, Liu P, Wang S, Huang YR, Chen XY, Zhou LX
Neural regeneration research 2023 Sep;18(9):1990-1998

Exo-miR-1290-induced by COX-2 overexpression promotes cancer-associated fibroblasts activation and tumor progression by CUL3-Nrf2 pathway in lung adenocarcinoma.

Bai X, Shao J, Duan T, Liu X, Wang M, Li X, You Q, Zhang Z, Pan J
Cell communication and signaling : CCS 2023 Sep 18;21(1):242

CircNCOA4 knockdown attenuates OGD-induced neuron injury through miR-338-5p/PDE4B axis.

Wang D, Xiao S, Li X, Qi W
Experimental brain research 2023 Oct;241(10):2561-2574

LDHA-regulated tumor-macrophage symbiosis promotes glioblastoma progression.

Khan F, Lin Y, Ali H, Pang L, Dunterman M, Hsu WH, Frenis K, Rowe RG, Wainwright D, McCortney K, Billingham L, Miska J, Horbinski C, Lesniak M, Chen P
Research square 2023 Oct 5;

Urinary exosome proteins PAK6 and EGFR as noninvasive diagnostic biomarkers of diabetic nephropathy.

Li T, Liu TC, Liu N, Li MJ, Zhang M
BMC nephrology 2023 Oct 3;24(1):291

Dysregulation of MicroRNAs Derived from Plasma Extracellular Vesicles in Schizoaffective Disorder.

Chen R, Shi J, Yang H, Zhang M, Chen Q, He Q
Molecular neurobiology 2023 Nov;60(11):6373-6382

Bone Marrow Stromal Cell-Secreted Extracellular Vesicles Containing miR-34c-5p Alleviate Lung Injury and Inflammation in Bronchopulmonary Dysplasia Through Promotion of PTEN Degradation by Targeting OTUD3.

He X, Kuang J, Wang Y, Lan G, Shi X
Immunological investigations 2023 Nov;52(6):681-702

M2 macrophage exosomal LINC01001 promotes non-small cell lung cancer development by affecting METTL3 and glycolysis pathway.

Xu L, Li K, Li J, Xu F, Liang S, Kong Y, Chen B
Cancer gene therapy 2023 Nov;30(11):1569-1580

Exosomal ZEB1 Derived from Neural Stem Cells Reduces Inflammation Injury in OGD/R-Treated Microglia via the GPR30-TLR4-NF-κB Axis.

Peng J, Yu Z, Xiao R, Hu X, Xia Y
Neurochemical research 2023 Jun;48(6):1811-1821

Exosomal ERBB2IP contributes to tumor growth via elevating PSAT1 expression in non-small cell lung carcinoma.

Peng X, Zhao L, Yao L, Dong J, Wu W, Luo T
Thoracic cancer 2023 Jul;14(19):1812-1823

Exosomal miR-543 derived from umbilical cord mesenchymal stem cells ameliorates endometrial fibrosis in intrauterine adhesion via downregulating N-cadherin.

Yuan D, Guo T, Qian H, Jin C, Ge H, Zhao Y, Zhu D, Lin M, Wang H, Yu H
Placenta 2023 Jan;131:75-81

A method for extraction of exosomes from breast tumour cells and characterisation by transmission electron microscopy.

Liu Z, Xue H, Chen Q, Yang G
Journal of microscopy 2023 Dec;292(3):117-122

LincRNA01703 Facilitates CD81(+) Exosome Secretion to Inhibit Lung Adenocarcinoma Metastasis via the Rab27a/SYTL1/CD81 Complex.

Huang Y, Guo S, Lin Y, Huo L, Yan H, Lin Z, Chen Z, Cai J, Wu J, Yuan J, Guan H, Wu G, Wu W, Tao T
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MicroRNAs in Small Extracellular Vesicles from Amniotic Fluid and Maternal Plasma Associated with Fetal Palate Development in Mice.

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International journal of molecular sciences 2023 Dec 6;24(24)

Hedgehog-Gli1-derived exosomal circ-0011536 mediates peripheral neural remodeling in pancreatic cancer by modulating the miR-451a/VGF axis.

Dai W, Wu X, Li J, Tang W, Wang Y, Xu W, Han D, Xu X, Xu X
Journal of experimental & clinical cancer research : CR 2023 Dec 2;42(1):329

MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer.

Huang J, Ding M, Lu Y, Xu L, Zhang Y, Han S, Zhu X, Li Y, Chen P
Cell death & disease 2023 Dec 1;14(12):789

Enhanced therapeutic effects of mesenchymal stem cell-derived extracellular vesicles within chitosan hydrogel in the treatment of diabetic foot ulcers.

Yang S, Chen S, Zhang C, Han J, Lin C, Zhao X, Guo H, Tan Y
Journal of materials science. Materials in medicine 2023 Aug 28;34(9):43

Circulating Exosomal miR-181b-5p Promoted Cell Senescence and Inhibited Angiogenesis to Impair Diabetic Foot Ulcer via the Nuclear Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Pathway.

Wang S, Shi M, Zhou J, Wang W, Zhang Y, Li Y
Frontiers in cardiovascular medicine 2022;9:844047

Adipose-Derived Stem Cell Exosomes Inhibit Hypertrophic Scaring Formation by Regulating Th17/Treg Cell Balance.

Wang H, Li Y, Yue Z, Liu Y, Chen Q, Hu D, Han J
BioMed research international 2022;2022:9899135

Exosomes Derived from microRNA-27a-3p Overexpressing Mesenchymal Stem Cells Inhibit the Progression of Liver Cancer through Suppression of Golgi Membrane Protein 1.

Bongolo CC, Thokerunga E, Yan Q, Yacouba MBM, Wang C
Stem cells international 2022;2022:9748714

Adipose-Derived Circulating Exosomes Promote Protection of the Pulmonary Endothelial Barrier by Inhibiting EndMT and Oxidative Stress through Down-Regulation of the TGF-β Pathway: A Potential Explanation for the Obesity Paradox in ARDS.

Qi D, Deng W, Chen X, Fan S, Peng J, Tang X, Wang D, Yu Q
Oxidative medicine and cellular longevity 2022;2022:5475832

Long Noncoding RNA SBF2-AS1 Promotes Abdominal Aortic Aneurysm Formation through the miRNA-520f-3p/SMARCD1 Axis.

Han B, Yang M, Liu Q, Wang G, Hou J
Disease markers 2022;2022:4782361

Keloid Patient Plasma-Derived Exosomal hsa_circ_0020792 Promotes Normal Skin Fibroblasts Proliferation, Migration, and Fibrogenesis via Modulating miR-193a-5p and Activating TGF-β1/Smad2/3 Signaling.

Hu H, Mao G, Zheng J, Guo F
Drug design, development and therapy 2022;16:4223-4234

Loss of exosomal micro-RNA-200b-3p from hypoxia cancer-associated fibroblasts reduces sensitivity to 5-flourouracil in colorectal cancer through targeting high-mobility group box 3.

Yuan H, Chen B, Chai R, Gong W, Wan Z, Zheng B, Hu X, Guo Y, Gao S, Dai Q, Yu P, Tu S
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Designer Exosomes for Targeted Delivery of a Novel Therapeutic Cargo to Enhance Sorafenib-Mediated Ferroptosis in Hepatocellular Carcinoma.

Li X, Yu Q, Zhao R, Guo X, Liu C, Zhang K, Zhang W, Liu J, Yu J, Wang S, Hao Q, Li W, Zhang W, Li M, Zhang Y, Zhang C, Gao Y
Frontiers in oncology 2022;12:898156

Downregulation of exosomal miR-7-5p promotes breast cancer migration and invasion by targeting RYK and participating in the atypical WNT signalling pathway.

Liang Z, Liu L, Gao R, Che C, Yang G
Cellular & molecular biology letters 2022 Oct 9;27(1):88

Exosomal circRNA Scm-like with four malignant brain tumor domains 2 (circ-SFMBT2) enhances the docetaxel resistance of prostate cancer via the microRNA-136-5p/tribbles homolog 1 pathway.

Tan X, Song X, Fan B, Li M, Zhang A, Pei L
Anti-cancer drugs 2022 Oct 1;33(9):871-882

Cancer-associated fibroblast-secreted miR-421 promotes pancreatic cancer by regulating the SIRT3/H3K9Ac/HIF-1α axis.

Zhou B, Lei JH, Wang Q, Qu TF, Cha LC, Zhan HX, Liu SL, Hu X, Sun CD, Guo WD, Qiu FB, Cao JY
The Kaohsiung journal of medical sciences 2022 Nov;38(11):1080-1092

Differential expression of exosomal microRNAs in fresh and senescent apheresis platelet concentrates.

Mi Z, Gong L, Kong Y, Zhao P, Yin Y, Xu H, Tian L, Liu Z
Platelets 2022 Nov 17;33(8):1260-1269

αvβ3-targeted sEVs for efficient intracellular delivery of proteins using MFG-E8.

Mai J, Wang K, Liu C, Xiong S, Xie Q
BMC biotechnology 2022 May 21;22(1):15

Reassessment of the Proteomic Composition and Function of Extracellular Vesicles in the Seminal Plasma.

Wang H, Zhu Y, Tang C, Zhou Z, Wang Z, Li Z, Zheng X, Chen S, Zhou Y, Liang A, Li Y, Lin Y, Sun F
Endocrinology 2022 Jan 1;163(1)

Two Small Extracellular Vesicle sRNAs Derived From Mycobacterium tuberculosis Serve as Diagnostic Biomarkers for Active Pulmonary Tuberculosis.

Lu G, Jiang X, Wu A, Zhou J, Liu H, He F, Zhang Q, Zen K, Gu S, Wang J
Frontiers in microbiology 2021;12:642559

Macrophage exosomes transfer angiotensin II type 1 receptor to lung fibroblasts mediating bleomycin-induced pulmonary fibrosis.

Sun NN, Zhang Y, Huang WH, Zheng BJ, Jin SY, Li X, Meng Y
Chinese medical journal 2021 Sep 2;134(18):2175-2185

Comparison of MicroRNA Profiles in Extracellular Vesicles from Small and Large Goat Follicular Fluid.

Ding Q, Jin M, Kalds P, Meng C, Wang H, Zhong J, Wang X, Chen Y
Animals : an open access journal from MDPI 2021 Nov 8;11(11)

Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis.

Li Y, Zhang J, Shi J, Liu K, Wang X, Jia Y, He T, Shen K, Wang Y, Liu J, Zhang W, Wang H, Zheng Z, Hu D
Stem cell research & therapy 2021 Mar 31;12(1):221

A novel strategy to identify candidate diagnostic and prognostic biomarkers for gastric cancer.

Liu L, Pang H, He Q, Pan B, Sun X, Shan J, Wu L, Wu K, Yao X, Guo Y
Cancer cell international 2021 Jul 2;21(1):335

Exosomes derived from thymic stromal lymphopoietin-treated dendritic cells regulate T helper 17/regulatory T cell differentiation via miR-21/Smad7 axis.

Ji Q, Liu J, Dong Y, Wang L, Dong K, Setiz B, Szentmáry N, Qu B, Shi L
Experimental cell research 2021 Jan 1;398(1):112393

Endothelial cell-derived exosomal circHIPK3 promotes the proliferation of vascular smooth muscle cells induced by high glucose via the miR-106a-5p/Foxo1/Vcam1 pathway.

Wang S, Shi M, Li J, Zhang Y, Wang W, Xu P, Li Y
Aging 2021 Dec 10;13(23):25241-25255

Exosomal circRNAs contribute to intestinal development via the VEGF signalling pathway in human term and preterm colostrum.

Zhou Y, Yu Z, Wang X, Chen W, Liu Y, Zhang Y, Yin J, Han S
Aging 2021 Apr 4;13(8):11218-11233

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