Antibody data
- Antibody Data
- Antigen structure
- References [124]
- Comments [0]
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- Product number
- 67605-1-Ig - Provider product page

- Provider
- Proteintech Group
- Product name
- CD63 antibody
- Antibody type
- Monoclonal
- Description
- CD63 antibody (Cat. #67605-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3D4D1
- Vial size
- 20ul, 150ul
Submitted references A fibroblast-specific miRNA functional cluster in remote exosomes aggravates myocardial ischaemia/reperfusion injury via the Rap1b/ERK1/2 axis.
Red Blood Cell-Derived Exosomes Deliver Complement C5 to Exacerbate Neuroinflammation and Neuronal Injury after Intracerebral Hemorrhage.
BMSC-derived extracellular vesicles enhance osteosarcoma proliferation and metastasis via the circRNA-0010220/β-catenin pathway.
Rapid and sensitive detection of cancer-derived small extracellular vesicles using Janus particles.
Hypoxia conditioned adipose-derived stem cell-derived extracellular vesicle therapy improves cardiac function in a rat model of ischemic cardiomyopathy.
PAM-assembled CRISPR-Cas12a activation-based fluorescent and colorimetric dual-modal biosensor for detecting prostate cancer exosomes.
Exosomes Derived from BMSCs Treated with CeONPs Ameliorate Radiation-Induced Jaw Bone Injury via miR-21-5p/STAT3 Axis-Mediated Osteogenesis and ROS Scavenging.
Caveolin-1 drives immunosuppression in esophageal squamous cell carcinoma by enhancing exosome secretion and macrophage M2 polarization via inhibition of MVB autophagic degradation.
Exosomal microRNAs of tuberculous pleural effusion orchestrating TGF-β signaling mediate pleural fibrosis.
Acutely denervated muscle EVs reshape neuronal mitochondrial metabolism via retrograde signaling to rescue peripheral nerve injury.
MiR-93-5p Loaded Lipid Nanoparticles Break the Dry Eye Vicious Cycle via Targeting MAP3K8.
5-hydroxymethylcytosine signature in plasma extracellular vesicle DNA as a diagnostic molecular biomarker for precancerous lesions of gastric cancer.
Safety, Efficacy and Bio-Distribution Analysis of Exosomes Derived From Human Umbilical Cord Mesenchymal Stem Cells for Effective Treatment of Bronchopulmonary Dysplasia by Intranasal Administration in Mice Model.
Serum Exosomes miR-122-5P Induces Hepatic and Renal Injury in Septic Rats by Regulating TAK1/SIRT1 Pathway.
Extracellular vesicles derived from irradiated oral squamous cell carcinoma cells inhibits M2 macrophage polarization by the miR-198-5p/MYD88 axis.
Glyphosate targets FYN to regulate glycolysis and promote glioblastoma proliferation: A network toxicology study.
Exosomal delivery of AZD5582 to overcome TRAIL resistance as an optimal therapy against triple-negative breast cancer.
Engineering of an Exosome-Based GPIHBP1 mRNA Delivery System for Efficient Therapy of Familial Hypertriglyceridemia.
Bisphenol A promotes OSCC progression via GABBR1-mediated MAPK signaling and macrophage polarization: A network toxicology based study.
Towards implementing optimized methodologies and in-depth molecular profiling to assess the pharmacological potential of human lung fibroblast exosomes as bio-shuttles for cancer therapeutics.
Proteomics Uncovers Enrichment Bias of Common Extracellular Vesicle Isolation Methods in HEK293T Cells.
Exosomal transfer of miR-375-3p from pancreatic β cells to hepatocytes impairs hepatic glycogenesis via Rbpj repression.
Protective effects of mouse bone marrow mesenchymal stem cell-derived extracellular vesicles on radiation-induced epididymal cells damage via USP44/RBM14 axis.
Microfluidics-based label-free SERS profiling of exosomes with machine learning for osteosarcoma diagnosis.
Change and significance of connexin 43 in saliva extracellular vesicles from oral lichen planus patients.
Choline Phosphate Surface-Activated 3D-Printed Porous Titanium Scaffold Combined with Stem Cell Exosomes for Enhancing Bone Defects Repair.
Microneedle-mediated hypoxic extracellular vesicle-encapsulated selenium nanoparticles delivery to treat androgenetic alopecia.
Tremella polysaccharide microneedles loaded with magnetic dental pulp stem cell intracellular vesicles used for androgenic alopecia.
Administration of Porphyromonas gingivalis in pregnant mice enhances glycolysis and histone lactylation/ADAM17 leading to cleft palate in offspring.
Macrophages-derived small extracellular vesicles regulate chondrocyte proliferation and affect osteoarthritis progression via upregulating Osteopontin expression.
Tumor exosomal circPTBP3 drives gastric cancer peritoneal metastasis via mesothelial-mesenchymal transition.
Transdermal psoriasis treatment inspired by tumor microenvironment-mediated immunomodulation and advanced by exosomal engineering.
Kasumi-1 exosome plays a major T-cell immune evasion role in TP53-type acute leukemia.
(124)I-labelled BMSC-Derived Extracellular Vesicles Deliver CRISPR/Cas9 Ribonucleoproteins With a GFP-Reporter System to Inhibit Osteosarcoma Proliferation and Metastasis.
Immunojanus Particles for low-volume and isolation-free unlabeled characterization of small Extracellular Vesicle in biofluids: Characterization of disease type by surface marker profiling.
Local Exosome Inhibition Potentiates Mild Photothermal Immunotherapy Against Breast Cancer.
Exosomal circ_0006896 promotes AML progression via interaction with HDAC1 and restriction of antitumor immunity.
Hypoxia-Challenged Pancreatic Adenocarcinoma Cell-Derived Exosomal circR3HCC1L Drives Tumor Growth Via Upregulating PKM2 Through Sequestering miR-873-5p.
Cardiac repair using regenerating neonatal heart tissue-derived extracellular vesicles.
The expression and clinical significance of serum exosomal-long non-coding RNA DLEU1 in patients with cervical cancer.
EXO/hydrogel system for sequential regulation of endogenous hyaline cartilage regeneration.
NAD(+) Enhanced Mesenchymal Stromal Cells Effect on Muscle Atrophy by Improving SIRT1-Mediated Mitochondrial Function via NAMPT.
Exosome-mediated modulation of macrophage polarization and inflammation in early Klebsiella pneumoniae lung infections.
Aberrant neuronal excitation promotes neuroinflammation in the primary motor cortex of ischemic stroke mice.
Adhesive hydrogel based on Konjac Glucomannan (KGM) loaded with siACTC1-exosomes for enhanced post-surgical keloid treatment.
hUC-MSCs and derived exosomes attenuate DEX-induced muscle atrophy through modulation of estrogen signaling pathway.
Exosome-derived Uc.339 as a potential biomarker for bone metastasis from pulmonary adenocarcinoma.
Engineered brain-targeting exosome for reprogramming immunosuppressive microenvironment of glioblastoma.
In vitro study on the promotion of osteogenic differentiation by mitochondrial-derived vesicles through activation of inflammation and reprogramming of metabolic pathways.
NOX2 and NOX4 expression in monocytes and macrophages-extracellular vesicles in signalling and therapeutics.
CircPRRC2C Promotes the Oncogenic Phenotypes of Laryngeal Squamous Cell Carcinoma Cells via MiR-136-5p/HOXD11 Axis.
Exosomal circZNF800 Derived from Glioma Stem-like Cells Regulates Glioblastoma Tumorigenicity via the PIEZO1/Akt Axis.
Hybrid hair follicle stem cell extracellular vesicles co-delivering finasteride and gold nanoparticles for androgenetic alopecia treatment.
Umbilical cord blood-derived exosomes attenuate dopaminergic neuron damage of Parkinson's disease mouse model.
Identification of novel biomarker hsa_circ_0003914 for rheumatoid arthritis from plasma exosomes.
CX3CR1(+)/UCHL1(+) microglial extracellular vesicles in blood: a potential biomarker for multiple sclerosis.
PF-PEG@ASIV-EXO Hydrogel Accelerates Diabetic Wound Healing by Ferroptosis Resistance and Promoting Angiogenesis.
Cellulose Nanofibrils of High Immunoaffinity for Efficient Enrichment of Small Extracellular Vesicles.
BMSCs-Derived Extracellular VesiclemiR-29a-3p Improved the Stability of Rat Myasthenia Gravis by Regulating Treg/Th17 Cells.
Mesenchymal stromal cells deliver H(2)S-enhanced Nrf2 via extracellular vesicles to mediate mitochondrial homeostasis for repairing hypoxia-ischemia brain damage.
Dexamethasone-Integrated Mesenchymal Stem Cells for Systemic Lupus Erythematosus Treatment via Multiple Immunomodulatory Mechanisms.
Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression.
Local Delivery of Dual Stem Cell-Derived Exosomes Using an Electrospun Nanofibrous Platform for the Treatment of Traumatic Brain Injury.
Exosomes derived from M2 macrophages promote fibroblast autophagy to contribute to hypertrophic scar formation via CXCL2/CXCR7/mTOR pathway.
Exploring the therapeutic potential of Sirt6-enriched adipose stem cell-derived exosomes in myocardial ischemia-reperfusion injury: unfolding new epigenetic frontiers.
Interorgan communication in neurogenic heterotopic ossification: the role of brain-derived extracellular vesicles.
In-situ gelation of fibrin gel encapsulating platelet-rich plasma-derived exosomes promotes rotator cuff healing.
Down-expression of miR-494-3p in senescent osteocyte-derived exosomes inhibits osteogenesis and accelerates age-related bone loss via PTEN/PI3K/AKT pathway.
Exosomes from adipose-derived stem cells overexpressing microRNA-671-3p promote fat graft angiogenesis and adipogenic differentiation.
Activating PKA signaling increases exosome production and attenuates cerebral ischemia-reperfusion injury by regulating Cx43 expression.
Huangqi-Danshen decoction improves heart failure by regulating pericardial adipose tissue derived extracellular vesicular miR-27a-3p to activate AMPKα2 mediated mitophagy.
Rapid evaluation of hepatocellular carcinoma by detecting plasma exosomes with time-resolved fluorescence immunochromatographic test strips.
IL-1β-induced mesenchymal stem cell-derived exosomes inhibit neuronal ferroptosis in intracerebral hemorrhage through the HSPA5/GPX4 axis.
Cutaneous squamous cell carcinoma-derived exosomal MicroRNA-31 acts as an oncogene by targeting the tumor suppressor RhoBTB1.
Molecular Profiling of A549 Cell-Derived Exosomes: Proteomic, miRNA, and Interactome Analysis for Identifying Potential Key Regulators in Lung Cancer.
JEV infection leads to dysfunction of lysosome by downregulating the expression of LAMP1 and LAMP2.
miR-200a-3p-enriched MSC-derived extracellular vesicles reverse erectile function in diabetic rats by targeting Keap1.
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
NADPH oxidase-dependent free radical generation and protein adduct formation in neutrophils.
Healthy Plasma Exosomes Exert Potential Neuroprotective Effects against Methylmalonic Acid-Induced Hippocampal Neuron Injury.
Hepatocyte-derived exosomes deliver the lncRNA CYTOR to hepatic stellate cells and promote liver fibrosis.
Enhancing Skin Injury Repair: Combined Application of PF-127 Hydrogel and hADSC-Exos Containing miR-148a-3p.
Tumor-derived extracellular vesicles as a biomarker for breast cancer diagnosis and metastasis monitoring.
Knockdown of AK142426 suppresses M2 macrophage polarization and inflammation in peritoneal fibrosis via binding to c-Jun.
Low-temperature 3D-printed collagen/chitosan scaffolds loaded with exosomes derived from neural stem cells pretreated with insulin growth factor-1 enhance neural regeneration after traumatic brain injury.
Exo-miR-1290-induced by COX-2 overexpression promotes cancer-associated fibroblasts activation and tumor progression by CUL3-Nrf2 pathway in lung adenocarcinoma.
CircNCOA4 knockdown attenuates OGD-induced neuron injury through miR-338-5p/PDE4B axis.
LDHA-regulated tumor-macrophage symbiosis promotes glioblastoma progression.
Urinary exosome proteins PAK6 and EGFR as noninvasive diagnostic biomarkers of diabetic nephropathy.
Dysregulation of MicroRNAs Derived from Plasma Extracellular Vesicles in Schizoaffective Disorder.
Bone Marrow Stromal Cell-Secreted Extracellular Vesicles Containing miR-34c-5p Alleviate Lung Injury and Inflammation in Bronchopulmonary Dysplasia Through Promotion of PTEN Degradation by Targeting OTUD3.
M2 macrophage exosomal LINC01001 promotes non-small cell lung cancer development by affecting METTL3 and glycolysis pathway.
Exosomal ZEB1 Derived from Neural Stem Cells Reduces Inflammation Injury in OGD/R-Treated Microglia via the GPR30-TLR4-NF-κB Axis.
Exosomal ERBB2IP contributes to tumor growth via elevating PSAT1 expression in non-small cell lung carcinoma.
Exosomal miR-543 derived from umbilical cord mesenchymal stem cells ameliorates endometrial fibrosis in intrauterine adhesion via downregulating N-cadherin.
A method for extraction of exosomes from breast tumour cells and characterisation by transmission electron microscopy.
LincRNA01703 Facilitates CD81(+) Exosome Secretion to Inhibit Lung Adenocarcinoma Metastasis via the Rab27a/SYTL1/CD81 Complex.
MicroRNAs in Small Extracellular Vesicles from Amniotic Fluid and Maternal Plasma Associated with Fetal Palate Development in Mice.
Hedgehog-Gli1-derived exosomal circ-0011536 mediates peripheral neural remodeling in pancreatic cancer by modulating the miR-451a/VGF axis.
MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer.
Enhanced therapeutic effects of mesenchymal stem cell-derived extracellular vesicles within chitosan hydrogel in the treatment of diabetic foot ulcers.
Circulating Exosomal miR-181b-5p Promoted Cell Senescence and Inhibited Angiogenesis to Impair Diabetic Foot Ulcer via the Nuclear Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Pathway.
Adipose-Derived Stem Cell Exosomes Inhibit Hypertrophic Scaring Formation by Regulating Th17/Treg Cell Balance.
Exosomes Derived from microRNA-27a-3p Overexpressing Mesenchymal Stem Cells Inhibit the Progression of Liver Cancer through Suppression of Golgi Membrane Protein 1.
Adipose-Derived Circulating Exosomes Promote Protection of the Pulmonary Endothelial Barrier by Inhibiting EndMT and Oxidative Stress through Down-Regulation of the TGF-β Pathway: A Potential Explanation for the Obesity Paradox in ARDS.
Long Noncoding RNA SBF2-AS1 Promotes Abdominal Aortic Aneurysm Formation through the miRNA-520f-3p/SMARCD1 Axis.
Keloid Patient Plasma-Derived Exosomal hsa_circ_0020792 Promotes Normal Skin Fibroblasts Proliferation, Migration, and Fibrogenesis via Modulating miR-193a-5p and Activating TGF-β1/Smad2/3 Signaling.
Loss of exosomal micro-RNA-200b-3p from hypoxia cancer-associated fibroblasts reduces sensitivity to 5-flourouracil in colorectal cancer through targeting high-mobility group box 3.
Designer Exosomes for Targeted Delivery of a Novel Therapeutic Cargo to Enhance Sorafenib-Mediated Ferroptosis in Hepatocellular Carcinoma.
Downregulation of exosomal miR-7-5p promotes breast cancer migration and invasion by targeting RYK and participating in the atypical WNT signalling pathway.
Exosomal circRNA Scm-like with four malignant brain tumor domains 2 (circ-SFMBT2) enhances the docetaxel resistance of prostate cancer via the microRNA-136-5p/tribbles homolog 1 pathway.
Cancer-associated fibroblast-secreted miR-421 promotes pancreatic cancer by regulating the SIRT3/H3K9Ac/HIF-1α axis.
Differential expression of exosomal microRNAs in fresh and senescent apheresis platelet concentrates.
αvβ3-targeted sEVs for efficient intracellular delivery of proteins using MFG-E8.
Reassessment of the Proteomic Composition and Function of Extracellular Vesicles in the Seminal Plasma.
Two Small Extracellular Vesicle sRNAs Derived From Mycobacterium tuberculosis Serve as Diagnostic Biomarkers for Active Pulmonary Tuberculosis.
Macrophage exosomes transfer angiotensin II type 1 receptor to lung fibroblasts mediating bleomycin-induced pulmonary fibrosis.
Comparison of MicroRNA Profiles in Extracellular Vesicles from Small and Large Goat Follicular Fluid.
Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis.
A novel strategy to identify candidate diagnostic and prognostic biomarkers for gastric cancer.
Exosomes derived from thymic stromal lymphopoietin-treated dendritic cells regulate T helper 17/regulatory T cell differentiation via miR-21/Smad7 axis.
Endothelial cell-derived exosomal circHIPK3 promotes the proliferation of vascular smooth muscle cells induced by high glucose via the miR-106a-5p/Foxo1/Vcam1 pathway.
Exosomal circRNAs contribute to intestinal development via the VEGF signalling pathway in human term and preterm colostrum.
MSC-derived exosomes promote recovery from traumatic brain injury via microglia/macrophages in rat.
Zhang R, Li M, Jin J, Fu X, Zhu H, Huang X, He M, Li Z, Lin R, Lin H, Zhang T, Liao W, Bin J, Wang Q, Zheng C, Liao Y
British journal of pharmacology 2026 Mar;183(5):1186-1204
British journal of pharmacology 2026 Mar;183(5):1186-1204
Red Blood Cell-Derived Exosomes Deliver Complement C5 to Exacerbate Neuroinflammation and Neuronal Injury after Intracerebral Hemorrhage.
Chen Q, Min J, Lu X, Gao Z, Xiong Y
Inflammation 2026 Mar 5;49(1)
Inflammation 2026 Mar 5;49(1)
BMSC-derived extracellular vesicles enhance osteosarcoma proliferation and metastasis via the circRNA-0010220/β-catenin pathway.
Pan R, Pan Y, Ruan W, Zheng H, Jiang G, Li J, Tian X, Sun L
Cell death & disease 2026 Mar 25;17(1)
Cell death & disease 2026 Mar 25;17(1)
Rapid and sensitive detection of cancer-derived small extracellular vesicles using Janus particles.
Kumar S, Sinclair JA, Shi T, Chuang HS, Senapati S, Chang HC
Nature biomedical engineering 2026 Mar 11;
Nature biomedical engineering 2026 Mar 11;
Hypoxia conditioned adipose-derived stem cell-derived extracellular vesicle therapy improves cardiac function in a rat model of ischemic cardiomyopathy.
Kumagai K, Kawamura T, Torigata K, Harada A, Kishimoto Y, Miyagawa S, Yoshikawa Y
Regenerative therapy 2026 Jun;32:101105
Regenerative therapy 2026 Jun;32:101105
PAM-assembled CRISPR-Cas12a activation-based fluorescent and colorimetric dual-modal biosensor for detecting prostate cancer exosomes.
Miao Y, Wang C, Peng Y, Sun X, Zheng Z, Zhang Q, Cheng W, Li J
Biosensors & bioelectronics 2026 Jul 15;304:118635
Biosensors & bioelectronics 2026 Jul 15;304:118635
Exosomes Derived from BMSCs Treated with CeONPs Ameliorate Radiation-Induced Jaw Bone Injury via miR-21-5p/STAT3 Axis-Mediated Osteogenesis and ROS Scavenging.
Zhang Z, Li H, Huang C, Mou T, Tian J, Ge Z, Zhao L, Wang D, Li C, Dai T, Zong C, Tian L
Pharmaceutics 2026 Feb 9;18(2)
Pharmaceutics 2026 Feb 9;18(2)
Caveolin-1 drives immunosuppression in esophageal squamous cell carcinoma by enhancing exosome secretion and macrophage M2 polarization via inhibition of MVB autophagic degradation.
Zhai KR, Zhao PL, Wang ZH, Feng HM, Li ZQ, Huang HR, Yang N, Su ZP, Cui BQ, Song TN, Li B
Journal of translational medicine 2026 Feb 4;24(1)
Journal of translational medicine 2026 Feb 4;24(1)
Exosomal microRNAs of tuberculous pleural effusion orchestrating TGF-β signaling mediate pleural fibrosis.
Jiang LJ, Zheng YY, Liang LM, Jia ZH, Du RH, Huang H, Dai X, Cheng PP, Zhao LQ, Li Q, Jiang YH, Cui XL, Ye SY, Hu SH, Zhang HD, Lian CY, Feng X, Song LJ, Yu F, He XL, Xiong L, Xiang F, Wang X, Liu AD, Wang M, Ye H, Ma WL
Respiratory research 2026 Feb 3;27(1)
Respiratory research 2026 Feb 3;27(1)
Acutely denervated muscle EVs reshape neuronal mitochondrial metabolism via retrograde signaling to rescue peripheral nerve injury.
Liu Q, Xue B, Zhang Y, Qin M, Zhu Z, Wang Z, Li H, Fan S, Su M, Li S, Yang S, Qin A, Ma T, Gao X, Sun H, Hao Y, Guo L, Nie S, Wang J, Luo Z, Huang J, Xia B
Cell reports. Medicine 2026 Feb 17;7(2):102585
Cell reports. Medicine 2026 Feb 17;7(2):102585
MiR-93-5p Loaded Lipid Nanoparticles Break the Dry Eye Vicious Cycle via Targeting MAP3K8.
Xu B, Ji X, Li L, Zhu L, Wang L, Kang J, Yang S, Fan T
ACS applied materials & interfaces 2026 Apr 8;18(13):18740-18754
ACS applied materials & interfaces 2026 Apr 8;18(13):18740-18754
5-hydroxymethylcytosine signature in plasma extracellular vesicle DNA as a diagnostic molecular biomarker for precancerous lesions of gastric cancer.
Chen H, Gao T, Chen H, Zhang L, Chen X, Duolikun M, Li X, Li X, Chen L, Gao H, Li Q, Hao X, Zhou P, Ren N, Lin J, Wang Y
Extracellular vesicles and circulating nucleic acids 2025;6(4):822-842
Extracellular vesicles and circulating nucleic acids 2025;6(4):822-842
Safety, Efficacy and Bio-Distribution Analysis of Exosomes Derived From Human Umbilical Cord Mesenchymal Stem Cells for Effective Treatment of Bronchopulmonary Dysplasia by Intranasal Administration in Mice Model.
Xu W, Jieda X, Wu Y, Du F, Ma L, Luo L, Liu D, Guo L, Liu J, Dong W
International journal of nanomedicine 2025;20:2521-2553
International journal of nanomedicine 2025;20:2521-2553
Serum Exosomes miR-122-5P Induces Hepatic and Renal Injury in Septic Rats by Regulating TAK1/SIRT1 Pathway.
Wang J, Jiang Y, Yuan Y, Ma X, Li T, Lv Y, Zhang J, Chen L, Zhou J, Meng Y, Zhang B, Dong X, Ma L
Infection and drug resistance 2025;18:185-197
Infection and drug resistance 2025;18:185-197
Extracellular vesicles derived from irradiated oral squamous cell carcinoma cells inhibits M2 macrophage polarization by the miR-198-5p/MYD88 axis.
Du X, Duan M, Zhang Y, Li R
International journal of radiation biology 2025;101(11):1117-1128
International journal of radiation biology 2025;101(11):1117-1128
Glyphosate targets FYN to regulate glycolysis and promote glioblastoma proliferation: A network toxicology study.
Ma A, Yang Z, He Q, Wang W, Ren H, Zhai C, Lan J
International journal of biological macromolecules 2025 Sep;321(Pt 3):146486
International journal of biological macromolecules 2025 Sep;321(Pt 3):146486
Exosomal delivery of AZD5582 to overcome TRAIL resistance as an optimal therapy against triple-negative breast cancer.
Zhang W, Li Q, Tian R, Deng Z, Sun R, Kuang X, Peng J, Xie B, Huang C, Yuan Z
Acta histochemica 2025 Sep;127(3):152270
Acta histochemica 2025 Sep;127(3):152270
Engineering of an Exosome-Based GPIHBP1 mRNA Delivery System for Efficient Therapy of Familial Hypertriglyceridemia.
Cao Y, Meng X, Xu X, Xia C, Yang C, Cui X, He Q, Song G
Journal of medicinal chemistry 2025 Sep 25;68(18):19554-19566
Journal of medicinal chemistry 2025 Sep 25;68(18):19554-19566
Bisphenol A promotes OSCC progression via GABBR1-mediated MAPK signaling and macrophage polarization: A network toxicology based study.
He Q, Ma A, Yang Z, Pang X, Li C, Diao J, Liu Y, Liu Q, Zhang Q, Dong Z, Zhang D
Ecotoxicology and environmental safety 2025 Sep 15;303:118835
Ecotoxicology and environmental safety 2025 Sep 15;303:118835
Towards implementing optimized methodologies and in-depth molecular profiling to assess the pharmacological potential of human lung fibroblast exosomes as bio-shuttles for cancer therapeutics.
Giannopoulos-Dimitriou A, Saiti A, Panteris E, Malousi A, Chatzopoulou F, Stamoula E, Anagnostopoulos AK, Vatsellas G, Al-Maghrabi PM, Müllertz A, Tseti I, Fatouros DG, Vizirianakis IS
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2025 Sep 1;212:107155
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2025 Sep 1;212:107155
Proteomics Uncovers Enrichment Bias of Common Extracellular Vesicle Isolation Methods in HEK293T Cells.
Fan S, Lin Y, Chen Z, Poetsch A
Journal of proteome research 2025 Oct 3;24(10):4900-4910
Journal of proteome research 2025 Oct 3;24(10):4900-4910
Exosomal transfer of miR-375-3p from pancreatic β cells to hepatocytes impairs hepatic glycogenesis via Rbpj repression.
Xu FZ, Dou L, Wu X, Xia CX, Yu DN, Man Y, Shen T, Huang XQ
World journal of diabetes 2025 Oct 15;16(10):109815
World journal of diabetes 2025 Oct 15;16(10):109815
Protective effects of mouse bone marrow mesenchymal stem cell-derived extracellular vesicles on radiation-induced epididymal cells damage via USP44/RBM14 axis.
Zhu L, Zhang J, Liang Y, Cheng Y, Lin N, Deng W, Lin L, Chen J
Stem cell research & therapy 2025 Nov 26;16(1):662
Stem cell research & therapy 2025 Nov 26;16(1):662
Microfluidics-based label-free SERS profiling of exosomes with machine learning for osteosarcoma diagnosis.
Jin Y, Zhang J, Wu X, Qu C, Fang X, Yang Y, Yuan Y, Liu H, Han Z
Talanta 2025 Nov 1;294:128276
Talanta 2025 Nov 1;294:128276
Change and significance of connexin 43 in saliva extracellular vesicles from oral lichen planus patients.
Yao C, Xin H, Liu S, Wang H, Ma Y, Yao C, Meng J
Archives of oral biology 2025 May;173:106217
Archives of oral biology 2025 May;173:106217
Choline Phosphate Surface-Activated 3D-Printed Porous Titanium Scaffold Combined with Stem Cell Exosomes for Enhancing Bone Defects Repair.
Cui X, Li J, Wang Y, Sun T, Weng J, Li Z, Li J, Chen X
ACS applied materials & interfaces 2025 May 14;17(19):27788-27805
ACS applied materials & interfaces 2025 May 14;17(19):27788-27805
Microneedle-mediated hypoxic extracellular vesicle-encapsulated selenium nanoparticles delivery to treat androgenetic alopecia.
Jing S, Liu Y, Wang B, Zhou H, Zhang H, Siwakoti P, Qu X, Ye P, He Y, Kumeria T, Ye Q
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113597
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113597
Tremella polysaccharide microneedles loaded with magnetic dental pulp stem cell intracellular vesicles used for androgenic alopecia.
Liu Y, Zhou H, Pang P, Liu Y, Situ J, Wang J, He Y, Ye Q
Stem cell research & therapy 2025 Mar 31;16(1):161
Stem cell research & therapy 2025 Mar 31;16(1):161
Administration of Porphyromonas gingivalis in pregnant mice enhances glycolysis and histone lactylation/ADAM17 leading to cleft palate in offspring.
Zhao X, Zheng X, Wang Y, Chen J, Wang X, Peng X, Yuan D, Liu Y, Wang Z, Du J
International journal of oral science 2025 Mar 13;17(1):18
International journal of oral science 2025 Mar 13;17(1):18
Macrophages-derived small extracellular vesicles regulate chondrocyte proliferation and affect osteoarthritis progression via upregulating Osteopontin expression.
Tu M, Liu AM, Huang W, Wang D, Chen HQ, Hu XY
Journal of cell communication and signaling 2025 Jun;19(2):e70008
Journal of cell communication and signaling 2025 Jun;19(2):e70008
Tumor exosomal circPTBP3 drives gastric cancer peritoneal metastasis via mesothelial-mesenchymal transition.
Dong C, Zhou Y, Shen X, Hu S, Duan K, Chen T, Li W, Sun X, Li P, Wang P, Han Y, Li D, Zhi Q, Zhou J
Cell death & disease 2025 Jun 11;16(1):444
Cell death & disease 2025 Jun 11;16(1):444
Transdermal psoriasis treatment inspired by tumor microenvironment-mediated immunomodulation and advanced by exosomal engineering.
Yang J, Zhu J, Lu S, Qin H, Zhou W
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113664
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113664
Kasumi-1 exosome plays a major T-cell immune evasion role in TP53-type acute leukemia.
Du Y, Fan Z, Li L, Xue Y, Zhao S
Immunobiology 2025 Jul;230(4):153102
Immunobiology 2025 Jul;230(4):153102
(124)I-labelled BMSC-Derived Extracellular Vesicles Deliver CRISPR/Cas9 Ribonucleoproteins With a GFP-Reporter System to Inhibit Osteosarcoma Proliferation and Metastasis.
Pan Y, Yang X, Zeng Z, Liu F, Luo J, Shen M, Zhou W, Li J, Jiang G, Sun L, Huang H, Pan R
Journal of extracellular vesicles 2025 Jul;14(7):e70130
Journal of extracellular vesicles 2025 Jul;14(7):e70130
Immunojanus Particles for low-volume and isolation-free unlabeled characterization of small Extracellular Vesicle in biofluids: Characterization of disease type by surface marker profiling.
Kumar S, Sinclair JA, Shi T, Chuang HS, Senapati S, Chang HC
bioRxiv : the preprint server for biology 2025 Jul 16;
bioRxiv : the preprint server for biology 2025 Jul 16;
Local Exosome Inhibition Potentiates Mild Photothermal Immunotherapy Against Breast Cancer.
Chen Q, Li Y, Hu J, Xu Z, Wang S, Cai N, He M, Xiao Y, Ding Y, Sun M, Li C, Cao Y, Wang Z, Zhou F, Wang G, Wang C, Tu J, Hu H, Sun C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(2):e2406328
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(2):e2406328
Exosomal circ_0006896 promotes AML progression via interaction with HDAC1 and restriction of antitumor immunity.
Can C, Yang X, Jia H, Wu H, Guo X, Wei Y, Jia Z, Liu W, Zhang A, He N, Zhang H, Ma D
Molecular cancer 2025 Jan 6;24(1):4
Molecular cancer 2025 Jan 6;24(1):4
Hypoxia-Challenged Pancreatic Adenocarcinoma Cell-Derived Exosomal circR3HCC1L Drives Tumor Growth Via Upregulating PKM2 Through Sequestering miR-873-5p.
Wang L, Zhou S, Ruan Y, Wu X, Zhang X, Li Y, Ying D, Lu Y, Tian Y, Cheng G, Zhang J, Lv K, Zhou X
Molecular biotechnology 2025 Feb;67(2):762-777
Molecular biotechnology 2025 Feb;67(2):762-777
Cardiac repair using regenerating neonatal heart tissue-derived extracellular vesicles.
Li H, Liu Y, Lin Y, Li S, Liu C, Cai A, Li W, Zhang W, Gao X, Ren Z, Ji H, Yu Y, Wang X, Ma W, Wang N, Zhao D, Li T, Liu Y, Cai B
Nature communications 2025 Feb 3;16(1):1292
Nature communications 2025 Feb 3;16(1):1292
The expression and clinical significance of serum exosomal-long non-coding RNA DLEU1 in patients with cervical cancer.
Chen Y, Cui F, Wu X, Zhao W, Xia Q
Annals of medicine 2025 Dec;57(1):2442537
Annals of medicine 2025 Dec;57(1):2442537
EXO/hydrogel system for sequential regulation of endogenous hyaline cartilage regeneration.
Wu K, Gong R, Gao T, Hu Y, Wang H, Zhang W, Wang X, Wang Y, Zhang N
Materials today. Bio 2025 Dec;35:102598
Materials today. Bio 2025 Dec;35:102598
NAD(+) Enhanced Mesenchymal Stromal Cells Effect on Muscle Atrophy by Improving SIRT1-Mediated Mitochondrial Function via NAMPT.
Song J, Sun Y, Zang N, Liu X, Chen J, Wang K, Xia L, Chen J, Zhao R, Liu F, Hou X, Chen L, Cheng J, Zhang W
Journal of cachexia, sarcopenia and muscle 2025 Dec;16(6):e70142
Journal of cachexia, sarcopenia and muscle 2025 Dec;16(6):e70142
Exosome-mediated modulation of macrophage polarization and inflammation in early Klebsiella pneumoniae lung infections.
Liu Z, Ren P, Xue Y, Liu S, Li S, Li Y, Zhang Y
Clinical science (London, England : 1979) 2025 Dec 23;139(24):1691-1707
Clinical science (London, England : 1979) 2025 Dec 23;139(24):1691-1707
Aberrant neuronal excitation promotes neuroinflammation in the primary motor cortex of ischemic stroke mice.
Li TT, Guo XF, Zhao YJ, Cheng YH, Xin DQ, Song Y, Liu DX, Wang Z
Acta pharmacologica Sinica 2025 Aug;46(8):2105-2119
Acta pharmacologica Sinica 2025 Aug;46(8):2105-2119
Adhesive hydrogel based on Konjac Glucomannan (KGM) loaded with siACTC1-exosomes for enhanced post-surgical keloid treatment.
Zhong Y, Zhang Y, Liu Y, Zeng K, Fan L, Wang Q, Zhang J
International journal of biological macromolecules 2025 Aug;319(Pt 3):145360
International journal of biological macromolecules 2025 Aug;319(Pt 3):145360
hUC-MSCs and derived exosomes attenuate DEX-induced muscle atrophy through modulation of estrogen signaling pathway.
Li N, Liu X, Wang Q, Chen Y, Han C, Qu C, Guan X, Zou W, Wang X, Li A, Zhang Y, Zhu L, Du R, Liu J, Wang Y
Stem cell research & therapy 2025 Aug 2;16(1):419
Stem cell research & therapy 2025 Aug 2;16(1):419
Exosome-derived Uc.339 as a potential biomarker for bone metastasis from pulmonary adenocarcinoma.
Lai W, Huang J, Lai X, Wang Y
Tissue & cell 2025 Apr;93:102747
Tissue & cell 2025 Apr;93:102747
Engineered brain-targeting exosome for reprogramming immunosuppressive microenvironment of glioblastoma.
Yang J, Li Y, Jiang S, Tian Y, Zhang M, Guo S, Wu P, Li J, Xu L, Li W, Wang Y, Gao H, Huang Y, Weng Y, Ruan S
Exploration (Beijing, China) 2025 Apr;5(2):20240039
Exploration (Beijing, China) 2025 Apr;5(2):20240039
In vitro study on the promotion of osteogenic differentiation by mitochondrial-derived vesicles through activation of inflammation and reprogramming of metabolic pathways.
Pan C, Cheng C, Zhong S, Li S, Tan W, Yao Y
Journal of orthopaedic surgery and research 2025 Apr 17;20(1):388
Journal of orthopaedic surgery and research 2025 Apr 17;20(1):388
NOX2 and NOX4 expression in monocytes and macrophages-extracellular vesicles in signalling and therapeutics.
Rathi D, Rossi C, Pospíšil P, Ramalingam Manoharan R, Talarico L, Magnani A, Prasad A
Frontiers in cell and developmental biology 2024;12:1342227
Frontiers in cell and developmental biology 2024;12:1342227
CircPRRC2C Promotes the Oncogenic Phenotypes of Laryngeal Squamous Cell Carcinoma Cells via MiR-136-5p/HOXD11 Axis.
Peng X, Chen X, Peng S, Chen Y, Li Y, Tian Y
Molecular biotechnology 2024 Sep;66(9):2381-2395
Molecular biotechnology 2024 Sep;66(9):2381-2395
Exosomal circZNF800 Derived from Glioma Stem-like Cells Regulates Glioblastoma Tumorigenicity via the PIEZO1/Akt Axis.
Zhang N, Wu P, Mu M, Niu C, Hu S
Molecular neurobiology 2024 Sep;61(9):6556-6571
Molecular neurobiology 2024 Sep;61(9):6556-6571
Hybrid hair follicle stem cell extracellular vesicles co-delivering finasteride and gold nanoparticles for androgenetic alopecia treatment.
Wu X, Huang X, Zhu Q, Zhang J, Hu J, Song Y, You Y, Zhu L, Lu J, Xu X, Chen M, Wang W, Song X, Ji J, Du Y
Journal of controlled release : official journal of the Controlled Release Society 2024 Sep;373:652-666
Journal of controlled release : official journal of the Controlled Release Society 2024 Sep;373:652-666
Umbilical cord blood-derived exosomes attenuate dopaminergic neuron damage of Parkinson's disease mouse model.
Ye J, Sun X, Jiang Q, Gui J, Feng S, Qin B, Xie L, Guo A, Dong J, Sang M
Journal of nanobiotechnology 2024 Sep 14;22(1):567
Journal of nanobiotechnology 2024 Sep 14;22(1):567
Identification of novel biomarker hsa_circ_0003914 for rheumatoid arthritis from plasma exosomes.
He Q, Sha X, Ji J, Liu W, Sun C, Gu Z
International immunopharmacology 2024 Sep 10;138:112562
International immunopharmacology 2024 Sep 10;138:112562
CX3CR1(+)/UCHL1(+) microglial extracellular vesicles in blood: a potential biomarker for multiple sclerosis.
Duan J, Lv A, Guo Z, Liu Q, Tian C, Yang Y, Bi J, Yu X, Peng G, Luo B, Cai Z, Xu B, Fu Y, Zhang J
Journal of neuroinflammation 2024 Oct 9;21(1):254
Journal of neuroinflammation 2024 Oct 9;21(1):254
PF-PEG@ASIV-EXO Hydrogel Accelerates Diabetic Wound Healing by Ferroptosis Resistance and Promoting Angiogenesis.
Xiong W, Zhang X, Hu J, Zou X, Huang H, Qu W, Cai S, Li C, Wei Y, Zhong X, Cai Z, Huang Z
ACS biomaterials science & engineering 2024 Oct 14;10(10):6263-6285
ACS biomaterials science & engineering 2024 Oct 14;10(10):6263-6285
Cellulose Nanofibrils of High Immunoaffinity for Efficient Enrichment of Small Extracellular Vesicles.
Wang Z, Dai J, He H, Si T, Ng K, Zheng S, Zhou X, Zhou Z, Yuan H, Yang M
Small methods 2024 Nov;8(11):e2400426
Small methods 2024 Nov;8(11):e2400426
BMSCs-Derived Extracellular VesiclemiR-29a-3p Improved the Stability of Rat Myasthenia Gravis by Regulating Treg/Th17 Cells.
Tang Z, Chen M, Chen C, Fan C, Huang J
Immunological investigations 2024 Nov;53(8):1422-1438
Immunological investigations 2024 Nov;53(8):1422-1438
Mesenchymal stromal cells deliver H(2)S-enhanced Nrf2 via extracellular vesicles to mediate mitochondrial homeostasis for repairing hypoxia-ischemia brain damage.
Gai C, Li T, Zhao Y, Cheng Y, Song Y, Luo Q, Liu D, Wang Z
Free radical biology & medicine 2024 Nov 20;225:528-545
Free radical biology & medicine 2024 Nov 20;225:528-545
Dexamethasone-Integrated Mesenchymal Stem Cells for Systemic Lupus Erythematosus Treatment via Multiple Immunomodulatory Mechanisms.
Ma W, Che J, Chen W, Wang D, Zhang H, Zhao Y
ACS nano 2024 May 21;18(20):13249-13265
ACS nano 2024 May 21;18(20):13249-13265
Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression.
Khan F, Lin Y, Ali H, Pang L, Dunterman M, Hsu WH, Frenis K, Grant Rowe R, Wainwright DA, McCortney K, Billingham LK, Miska J, Horbinski C, Lesniak MS, Chen P
Nature communications 2024 Mar 5;15(1):1987
Nature communications 2024 Mar 5;15(1):1987
Local Delivery of Dual Stem Cell-Derived Exosomes Using an Electrospun Nanofibrous Platform for the Treatment of Traumatic Brain Injury.
Li J, Li X, Li X, Liang Z, Wang Z, Shahzad KA, Xu M, Tan F
ACS applied materials & interfaces 2024 Jul 24;16(29):37497-37512
ACS applied materials & interfaces 2024 Jul 24;16(29):37497-37512
Exosomes derived from M2 macrophages promote fibroblast autophagy to contribute to hypertrophic scar formation via CXCL2/CXCR7/mTOR pathway.
Shi M, Zhang L, Bi F, Ma X
Human & experimental toxicology 2024 Jan-Dec;43:9603271241303320
Human & experimental toxicology 2024 Jan-Dec;43:9603271241303320
Exploring the therapeutic potential of Sirt6-enriched adipose stem cell-derived exosomes in myocardial ischemia-reperfusion injury: unfolding new epigenetic frontiers.
Liu K, Wang H, Wang Y, Zhang X, Wang R, Zhang Z, Wang J, Lu X, Wu X, Han Y
Clinical epigenetics 2024 Jan 3;16(1):7
Clinical epigenetics 2024 Jan 3;16(1):7
Interorgan communication in neurogenic heterotopic ossification: the role of brain-derived extracellular vesicles.
Lu W, Yan J, Wang C, Qin W, Han X, Qin Z, Wei Y, Xu H, Gao J, Gao C, Ye T, Tay FR, Niu L, Jiao K
Bone research 2024 Feb 22;12(1):11
Bone research 2024 Feb 22;12(1):11
In-situ gelation of fibrin gel encapsulating platelet-rich plasma-derived exosomes promotes rotator cuff healing.
Li M, Shi L, Chen X, Yi D, Ding Y, Chen J, Xing G, Chen S, Wang L, Zhang Y, Zhu Y, Wang Y
Communications biology 2024 Feb 20;7(1):205
Communications biology 2024 Feb 20;7(1):205
Down-expression of miR-494-3p in senescent osteocyte-derived exosomes inhibits osteogenesis and accelerates age-related bone loss via PTEN/PI3K/AKT pathway.
Yao C, Sun J, Luo W, Chen H, Chen T, Chen C, Zhang B, Zhang Y
Bone & joint research 2024 Feb 1;13(2):52-65
Bone & joint research 2024 Feb 1;13(2):52-65
Exosomes from adipose-derived stem cells overexpressing microRNA-671-3p promote fat graft angiogenesis and adipogenic differentiation.
Hao X, Guo Y, Yu X, He L, He Y, Shu M
Tissue & cell 2024 Dec;91:102575
Tissue & cell 2024 Dec;91:102575
Activating PKA signaling increases exosome production and attenuates cerebral ischemia-reperfusion injury by regulating Cx43 expression.
Chen W, Qin Y, Wang Z, Chen P, Zhu G, Li S, Wang H, Liu X, Chen M, Li Z, Ye G
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2024 Dec;33(12):108000
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2024 Dec;33(12):108000
Huangqi-Danshen decoction improves heart failure by regulating pericardial adipose tissue derived extracellular vesicular miR-27a-3p to activate AMPKα2 mediated mitophagy.
Chen Z, Zhang M, Xu Q, Lu P, Liu M, Yin R, Liu X, Dai Y, Gao X, Gong J, Zhang S, Wang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156187
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156187
Rapid evaluation of hepatocellular carcinoma by detecting plasma exosomes with time-resolved fluorescence immunochromatographic test strips.
Li J, Su J, Li M, Wu Y, Chen H, Fu X, Yao H, Chen J, Liu Y, Zan J
Mikrochimica acta 2024 Dec 28;192(1):39
Mikrochimica acta 2024 Dec 28;192(1):39
IL-1β-induced mesenchymal stem cell-derived exosomes inhibit neuronal ferroptosis in intracerebral hemorrhage through the HSPA5/GPX4 axis.
Li J, Lin L, Yu Z, He J, Li Y, Jiang J, Xia Y
Brain research 2024 Dec 15;1845:149219
Brain research 2024 Dec 15;1845:149219
Cutaneous squamous cell carcinoma-derived exosomal MicroRNA-31 acts as an oncogene by targeting the tumor suppressor RhoBTB1.
Mu Y, Lian C, Chen X, Yang X, Li D, Zhang Y
Archives of dermatological research 2024 Dec 14;317(1):114
Archives of dermatological research 2024 Dec 14;317(1):114
Molecular Profiling of A549 Cell-Derived Exosomes: Proteomic, miRNA, and Interactome Analysis for Identifying Potential Key Regulators in Lung Cancer.
Giannopoulos-Dimitriou A, Saiti A, Malousi A, Anagnostopoulos AK, Vatsellas G, Al-Maghrabi PM, Müllertz A, Fatouros DG, Vizirianakis IS
Cancers 2024 Dec 10;16(24)
Cancers 2024 Dec 10;16(24)
JEV infection leads to dysfunction of lysosome by downregulating the expression of LAMP1 and LAMP2.
Yang X, Wang Z, Xie S, Liang Z, Wei N, Pan J, Zhao Y, Cao R
Veterinary microbiology 2024 Aug;295:110150
Veterinary microbiology 2024 Aug;295:110150
miR-200a-3p-enriched MSC-derived extracellular vesicles reverse erectile function in diabetic rats by targeting Keap1.
Zhang J, Zhao D, Zang Z, Ruan Z, Fu Q, Zhang K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:116964
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:116964
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
Jiang Y, Wang Y, Chen G, Sun F, Wu Q, Huang Q, Zeng D, Qiu W, Wang J, Yao Z, Liang B, Li S, Wu J, Huang N, Wang Y, Chen J, Zhai X, Huang L, Xu B, Yamamoto M, Tsukamoto T, Nomura S, Liao W, Shi M
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
NADPH oxidase-dependent free radical generation and protein adduct formation in neutrophils.
Manoharan RR, Zachová K, Buzáš M, Pospíšil P, Křupka M, Prasad A
RSC advances 2024 Aug 5;14(34):24765-24780
RSC advances 2024 Aug 5;14(34):24765-24780
Healthy Plasma Exosomes Exert Potential Neuroprotective Effects against Methylmalonic Acid-Induced Hippocampal Neuron Injury.
Zhou W, Li H, Song J, Suo F, Gu M, Qi S
ACS chemical neuroscience 2024 Aug 21;15(16):3022-3033
ACS chemical neuroscience 2024 Aug 21;15(16):3022-3033
Hepatocyte-derived exosomes deliver the lncRNA CYTOR to hepatic stellate cells and promote liver fibrosis.
Xu W, Mo W, Han D, Dai W, Xu X, Li J, Xu X
Journal of cellular and molecular medicine 2024 Apr;28(8):e18234
Journal of cellular and molecular medicine 2024 Apr;28(8):e18234
Enhancing Skin Injury Repair: Combined Application of PF-127 Hydrogel and hADSC-Exos Containing miR-148a-3p.
Zhang Q, Su P, Zhao F, Ren H, He C, Wu Q, Wang Z, Ma J, Huang X, Wang Z
ACS biomaterials science & engineering 2024 Apr 8;10(4):2235-2250
ACS biomaterials science & engineering 2024 Apr 8;10(4):2235-2250
Tumor-derived extracellular vesicles as a biomarker for breast cancer diagnosis and metastasis monitoring.
Xu F, Wang K, Zhu C, Fan L, Zhu Y, Wang JF, Li X, Liu Y, Zhao Y, Zhu C, Zhang W, Yang F, Xu J, Li Z, Guan X
iScience 2024 Apr 19;27(4):109506
iScience 2024 Apr 19;27(4):109506
Knockdown of AK142426 suppresses M2 macrophage polarization and inflammation in peritoneal fibrosis via binding to c-Jun.
Shao Q, Jiang C, Zhang Q, Liu J, Jin B, Zhao M, Xia Y
The journal of gene medicine 2023 Sep;25(9):e3524
The journal of gene medicine 2023 Sep;25(9):e3524
Low-temperature 3D-printed collagen/chitosan scaffolds loaded with exosomes derived from neural stem cells pretreated with insulin growth factor-1 enhance neural regeneration after traumatic brain injury.
Liu XY, Feng YH, Feng QB, Zhang JY, Zhong L, Liu P, Wang S, Huang YR, Chen XY, Zhou LX
Neural regeneration research 2023 Sep;18(9):1990-1998
Neural regeneration research 2023 Sep;18(9):1990-1998
Exo-miR-1290-induced by COX-2 overexpression promotes cancer-associated fibroblasts activation and tumor progression by CUL3-Nrf2 pathway in lung adenocarcinoma.
Bai X, Shao J, Duan T, Liu X, Wang M, Li X, You Q, Zhang Z, Pan J
Cell communication and signaling : CCS 2023 Sep 18;21(1):242
Cell communication and signaling : CCS 2023 Sep 18;21(1):242
CircNCOA4 knockdown attenuates OGD-induced neuron injury through miR-338-5p/PDE4B axis.
Wang D, Xiao S, Li X, Qi W
Experimental brain research 2023 Oct;241(10):2561-2574
Experimental brain research 2023 Oct;241(10):2561-2574
LDHA-regulated tumor-macrophage symbiosis promotes glioblastoma progression.
Khan F, Lin Y, Ali H, Pang L, Dunterman M, Hsu WH, Frenis K, Rowe RG, Wainwright D, McCortney K, Billingham L, Miska J, Horbinski C, Lesniak M, Chen P
Research square 2023 Oct 5;
Research square 2023 Oct 5;
Urinary exosome proteins PAK6 and EGFR as noninvasive diagnostic biomarkers of diabetic nephropathy.
Li T, Liu TC, Liu N, Li MJ, Zhang M
BMC nephrology 2023 Oct 3;24(1):291
BMC nephrology 2023 Oct 3;24(1):291
Dysregulation of MicroRNAs Derived from Plasma Extracellular Vesicles in Schizoaffective Disorder.
Chen R, Shi J, Yang H, Zhang M, Chen Q, He Q
Molecular neurobiology 2023 Nov;60(11):6373-6382
Molecular neurobiology 2023 Nov;60(11):6373-6382
Bone Marrow Stromal Cell-Secreted Extracellular Vesicles Containing miR-34c-5p Alleviate Lung Injury and Inflammation in Bronchopulmonary Dysplasia Through Promotion of PTEN Degradation by Targeting OTUD3.
He X, Kuang J, Wang Y, Lan G, Shi X
Immunological investigations 2023 Nov;52(6):681-702
Immunological investigations 2023 Nov;52(6):681-702
M2 macrophage exosomal LINC01001 promotes non-small cell lung cancer development by affecting METTL3 and glycolysis pathway.
Xu L, Li K, Li J, Xu F, Liang S, Kong Y, Chen B
Cancer gene therapy 2023 Nov;30(11):1569-1580
Cancer gene therapy 2023 Nov;30(11):1569-1580
Exosomal ZEB1 Derived from Neural Stem Cells Reduces Inflammation Injury in OGD/R-Treated Microglia via the GPR30-TLR4-NF-κB Axis.
Peng J, Yu Z, Xiao R, Hu X, Xia Y
Neurochemical research 2023 Jun;48(6):1811-1821
Neurochemical research 2023 Jun;48(6):1811-1821
Exosomal ERBB2IP contributes to tumor growth via elevating PSAT1 expression in non-small cell lung carcinoma.
Peng X, Zhao L, Yao L, Dong J, Wu W, Luo T
Thoracic cancer 2023 Jul;14(19):1812-1823
Thoracic cancer 2023 Jul;14(19):1812-1823
Exosomal miR-543 derived from umbilical cord mesenchymal stem cells ameliorates endometrial fibrosis in intrauterine adhesion via downregulating N-cadherin.
Yuan D, Guo T, Qian H, Jin C, Ge H, Zhao Y, Zhu D, Lin M, Wang H, Yu H
Placenta 2023 Jan;131:75-81
Placenta 2023 Jan;131:75-81
A method for extraction of exosomes from breast tumour cells and characterisation by transmission electron microscopy.
Liu Z, Xue H, Chen Q, Yang G
Journal of microscopy 2023 Dec;292(3):117-122
Journal of microscopy 2023 Dec;292(3):117-122
LincRNA01703 Facilitates CD81(+) Exosome Secretion to Inhibit Lung Adenocarcinoma Metastasis via the Rab27a/SYTL1/CD81 Complex.
Huang Y, Guo S, Lin Y, Huo L, Yan H, Lin Z, Chen Z, Cai J, Wu J, Yuan J, Guan H, Wu G, Wu W, Tao T
Cancers 2023 Dec 9;15(24)
Cancers 2023 Dec 9;15(24)
MicroRNAs in Small Extracellular Vesicles from Amniotic Fluid and Maternal Plasma Associated with Fetal Palate Development in Mice.
Zhao X, Peng X, Wang Z, Zheng X, Wang X, Wang Y, Chen J, Yuan D, Liu Y, Du J
International journal of molecular sciences 2023 Dec 6;24(24)
International journal of molecular sciences 2023 Dec 6;24(24)
Hedgehog-Gli1-derived exosomal circ-0011536 mediates peripheral neural remodeling in pancreatic cancer by modulating the miR-451a/VGF axis.
Dai W, Wu X, Li J, Tang W, Wang Y, Xu W, Han D, Xu X, Xu X
Journal of experimental & clinical cancer research : CR 2023 Dec 2;42(1):329
Journal of experimental & clinical cancer research : CR 2023 Dec 2;42(1):329
MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer.
Huang J, Ding M, Lu Y, Xu L, Zhang Y, Han S, Zhu X, Li Y, Chen P
Cell death & disease 2023 Dec 1;14(12):789
Cell death & disease 2023 Dec 1;14(12):789
Enhanced therapeutic effects of mesenchymal stem cell-derived extracellular vesicles within chitosan hydrogel in the treatment of diabetic foot ulcers.
Yang S, Chen S, Zhang C, Han J, Lin C, Zhao X, Guo H, Tan Y
Journal of materials science. Materials in medicine 2023 Aug 28;34(9):43
Journal of materials science. Materials in medicine 2023 Aug 28;34(9):43
Circulating Exosomal miR-181b-5p Promoted Cell Senescence and Inhibited Angiogenesis to Impair Diabetic Foot Ulcer via the Nuclear Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Pathway.
Wang S, Shi M, Zhou J, Wang W, Zhang Y, Li Y
Frontiers in cardiovascular medicine 2022;9:844047
Frontiers in cardiovascular medicine 2022;9:844047
Adipose-Derived Stem Cell Exosomes Inhibit Hypertrophic Scaring Formation by Regulating Th17/Treg Cell Balance.
Wang H, Li Y, Yue Z, Liu Y, Chen Q, Hu D, Han J
BioMed research international 2022;2022:9899135
BioMed research international 2022;2022:9899135
Exosomes Derived from microRNA-27a-3p Overexpressing Mesenchymal Stem Cells Inhibit the Progression of Liver Cancer through Suppression of Golgi Membrane Protein 1.
Bongolo CC, Thokerunga E, Yan Q, Yacouba MBM, Wang C
Stem cells international 2022;2022:9748714
Stem cells international 2022;2022:9748714
Adipose-Derived Circulating Exosomes Promote Protection of the Pulmonary Endothelial Barrier by Inhibiting EndMT and Oxidative Stress through Down-Regulation of the TGF-β Pathway: A Potential Explanation for the Obesity Paradox in ARDS.
Qi D, Deng W, Chen X, Fan S, Peng J, Tang X, Wang D, Yu Q
Oxidative medicine and cellular longevity 2022;2022:5475832
Oxidative medicine and cellular longevity 2022;2022:5475832
Long Noncoding RNA SBF2-AS1 Promotes Abdominal Aortic Aneurysm Formation through the miRNA-520f-3p/SMARCD1 Axis.
Han B, Yang M, Liu Q, Wang G, Hou J
Disease markers 2022;2022:4782361
Disease markers 2022;2022:4782361
Keloid Patient Plasma-Derived Exosomal hsa_circ_0020792 Promotes Normal Skin Fibroblasts Proliferation, Migration, and Fibrogenesis via Modulating miR-193a-5p and Activating TGF-β1/Smad2/3 Signaling.
Hu H, Mao G, Zheng J, Guo F
Drug design, development and therapy 2022;16:4223-4234
Drug design, development and therapy 2022;16:4223-4234
Loss of exosomal micro-RNA-200b-3p from hypoxia cancer-associated fibroblasts reduces sensitivity to 5-flourouracil in colorectal cancer through targeting high-mobility group box 3.
Yuan H, Chen B, Chai R, Gong W, Wan Z, Zheng B, Hu X, Guo Y, Gao S, Dai Q, Yu P, Tu S
Frontiers in oncology 2022;12:920131
Frontiers in oncology 2022;12:920131
Designer Exosomes for Targeted Delivery of a Novel Therapeutic Cargo to Enhance Sorafenib-Mediated Ferroptosis in Hepatocellular Carcinoma.
Li X, Yu Q, Zhao R, Guo X, Liu C, Zhang K, Zhang W, Liu J, Yu J, Wang S, Hao Q, Li W, Zhang W, Li M, Zhang Y, Zhang C, Gao Y
Frontiers in oncology 2022;12:898156
Frontiers in oncology 2022;12:898156
Downregulation of exosomal miR-7-5p promotes breast cancer migration and invasion by targeting RYK and participating in the atypical WNT signalling pathway.
Liang Z, Liu L, Gao R, Che C, Yang G
Cellular & molecular biology letters 2022 Oct 9;27(1):88
Cellular & molecular biology letters 2022 Oct 9;27(1):88
Exosomal circRNA Scm-like with four malignant brain tumor domains 2 (circ-SFMBT2) enhances the docetaxel resistance of prostate cancer via the microRNA-136-5p/tribbles homolog 1 pathway.
Tan X, Song X, Fan B, Li M, Zhang A, Pei L
Anti-cancer drugs 2022 Oct 1;33(9):871-882
Anti-cancer drugs 2022 Oct 1;33(9):871-882
Cancer-associated fibroblast-secreted miR-421 promotes pancreatic cancer by regulating the SIRT3/H3K9Ac/HIF-1α axis.
Zhou B, Lei JH, Wang Q, Qu TF, Cha LC, Zhan HX, Liu SL, Hu X, Sun CD, Guo WD, Qiu FB, Cao JY
The Kaohsiung journal of medical sciences 2022 Nov;38(11):1080-1092
The Kaohsiung journal of medical sciences 2022 Nov;38(11):1080-1092
Differential expression of exosomal microRNAs in fresh and senescent apheresis platelet concentrates.
Mi Z, Gong L, Kong Y, Zhao P, Yin Y, Xu H, Tian L, Liu Z
Platelets 2022 Nov 17;33(8):1260-1269
Platelets 2022 Nov 17;33(8):1260-1269
αvβ3-targeted sEVs for efficient intracellular delivery of proteins using MFG-E8.
Mai J, Wang K, Liu C, Xiong S, Xie Q
BMC biotechnology 2022 May 21;22(1):15
BMC biotechnology 2022 May 21;22(1):15
Reassessment of the Proteomic Composition and Function of Extracellular Vesicles in the Seminal Plasma.
Wang H, Zhu Y, Tang C, Zhou Z, Wang Z, Li Z, Zheng X, Chen S, Zhou Y, Liang A, Li Y, Lin Y, Sun F
Endocrinology 2022 Jan 1;163(1)
Endocrinology 2022 Jan 1;163(1)
Two Small Extracellular Vesicle sRNAs Derived From Mycobacterium tuberculosis Serve as Diagnostic Biomarkers for Active Pulmonary Tuberculosis.
Lu G, Jiang X, Wu A, Zhou J, Liu H, He F, Zhang Q, Zen K, Gu S, Wang J
Frontiers in microbiology 2021;12:642559
Frontiers in microbiology 2021;12:642559
Macrophage exosomes transfer angiotensin II type 1 receptor to lung fibroblasts mediating bleomycin-induced pulmonary fibrosis.
Sun NN, Zhang Y, Huang WH, Zheng BJ, Jin SY, Li X, Meng Y
Chinese medical journal 2021 Sep 2;134(18):2175-2185
Chinese medical journal 2021 Sep 2;134(18):2175-2185
Comparison of MicroRNA Profiles in Extracellular Vesicles from Small and Large Goat Follicular Fluid.
Ding Q, Jin M, Kalds P, Meng C, Wang H, Zhong J, Wang X, Chen Y
Animals : an open access journal from MDPI 2021 Nov 8;11(11)
Animals : an open access journal from MDPI 2021 Nov 8;11(11)
Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis.
Li Y, Zhang J, Shi J, Liu K, Wang X, Jia Y, He T, Shen K, Wang Y, Liu J, Zhang W, Wang H, Zheng Z, Hu D
Stem cell research & therapy 2021 Mar 31;12(1):221
Stem cell research & therapy 2021 Mar 31;12(1):221
A novel strategy to identify candidate diagnostic and prognostic biomarkers for gastric cancer.
Liu L, Pang H, He Q, Pan B, Sun X, Shan J, Wu L, Wu K, Yao X, Guo Y
Cancer cell international 2021 Jul 2;21(1):335
Cancer cell international 2021 Jul 2;21(1):335
Exosomes derived from thymic stromal lymphopoietin-treated dendritic cells regulate T helper 17/regulatory T cell differentiation via miR-21/Smad7 axis.
Ji Q, Liu J, Dong Y, Wang L, Dong K, Setiz B, Szentmáry N, Qu B, Shi L
Experimental cell research 2021 Jan 1;398(1):112393
Experimental cell research 2021 Jan 1;398(1):112393
Endothelial cell-derived exosomal circHIPK3 promotes the proliferation of vascular smooth muscle cells induced by high glucose via the miR-106a-5p/Foxo1/Vcam1 pathway.
Wang S, Shi M, Li J, Zhang Y, Wang W, Xu P, Li Y
Aging 2021 Dec 10;13(23):25241-25255
Aging 2021 Dec 10;13(23):25241-25255
Exosomal circRNAs contribute to intestinal development via the VEGF signalling pathway in human term and preterm colostrum.
Zhou Y, Yu Z, Wang X, Chen W, Liu Y, Zhang Y, Yin J, Han S
Aging 2021 Apr 4;13(8):11218-11233
Aging 2021 Apr 4;13(8):11218-11233
MSC-derived exosomes promote recovery from traumatic brain injury via microglia/macrophages in rat.
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