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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Immunocytochemistry [1]
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- Product number
- HPA038637 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA038637, RRID:AB_10672522
- Product name
- Anti-FAM111B
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human FAM111B, Gene description: family with sequence similarity 111, member B, Alternative Gene Names: CANP, Validated applications: ICC, IHC, WB, Uniprot ID: Q6SJ93, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.4 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Adenovirus E1B-55K controls SUMO-dependent degradation of antiviral cellular restriction factors
Loss of FAM111B protease mutated in hereditary fibrosing poikiloderma negatively regulates telomere length
Differential Regulation of Cellular FAM111B by Human Adenovirus C Type 5 E1 Oncogenes
FAM111 protease activity undermines cellular fitness and is amplified by gain‐of‐function mutations in human disease
FAM111B enhances proliferation of KRAS‐driven lung adenocarcinoma by degrading p16
Ip W, Tatham M, Krohne S, Gruhne J, Melling M, Meyer T, Gornott B, Bertzbach L, Hay R, Rodriguez E, Dobner T, Banks L
Journal of Virology 2023;97(11)
Journal of Virology 2023;97(11)
Loss of FAM111B protease mutated in hereditary fibrosing poikiloderma negatively regulates telomere length
Kliszczak M, Moralli D, Jankowska J, Bryjka P, Subha Meem L, Goncalves T, Hester S, Fischer R, Clynes D, Green C
Frontiers in Cell and Developmental Biology 2023;11
Frontiers in Cell and Developmental Biology 2023;11
Differential Regulation of Cellular FAM111B by Human Adenovirus C Type 5 E1 Oncogenes
Ip W, Wilkens B, Solomatina A, Martin J, Melling M, Hidalgo P, Bertzbach L, Speiseder T, Dobner T
Viruses 2021;13(6):1015
Viruses 2021;13(6):1015
FAM111 protease activity undermines cellular fitness and is amplified by gain‐of‐function mutations in human disease
Hoffmann S, Pentakota S, Mund A, Haahr P, Coscia F, Gallo M, Mann M, Taylor N, Mailand N
EMBO reports 2020;21(10)
EMBO reports 2020;21(10)
FAM111B enhances proliferation of KRAS‐driven lung adenocarcinoma by degrading p16
Kawasaki K, Nojima S, Hijiki S, Tahara S, Ohshima K, Matsui T, Hori Y, Kurashige M, Umeda D, Kiyokawa H, Kido K, Okuzaki D, Morii E
Cancer Science 2020;111(7):2635-2646
Cancer Science 2020;111(7):2635-2646
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line U-2 OS shows localization to nucleus & cytosol.
- Sample type
- Human
