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- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Immunocytochemistry [2]
- Immunohistochemistry [4]
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- Product number
- PA5-58474 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- FAM111B Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant protein fragment
- Description
- Immunogen sequence: SMKTEENKSF SAMEDDQRTR PEVSKDTVMK QTHADTPVDH CLSGIRKCSS TFKLKSEVNK HETALEMQNP NLNNKECCFT FTLNGNS Highest antigen sequence identity to the following orthologs: Mouse - 27%, Rat - 24%.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.4 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references FAM111B, a direct target of p53, promotes the malignant process of lung adenocarcinoma.
Sun H, Liu K, Huang J, Sun Q, Shao C, Luo J, Xu L, Shen Y, Ren B
OncoTargets and therapy 2019;12:2829-2842
OncoTargets and therapy 2019;12:2829-2842
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of FAM111B in human cell line U-2 OS shows positivity in nucleus & cytoplasm. Samples were probed using a FAM111B Polyclonal Antibody (Product # PA5-58474).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorecent analysis of FAM111B in human cell line U-2 OS using FAM111B Polyclonal Antibody (Product # PA5-58474). Staining shows localization to nucleus and cytosol.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of FAM111B in human rectum using FAM111B Polyclonal Antibody (Product # PA5-58474) shows moderate nuclear positivity in glandular cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of FAM111B in human skeletal muscle using FAM111B Polyclonal Antibody (Product # PA5-58474) shows no nuclear positivity in myocytes as expected.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of FAM111B in human tonsil using a FAM111B Polyclonal Antibody (Product # PA5-58474) shows moderate nuclear and cytoplasmic positivity in germinal and non-germinal center cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of FAM111B in human skin using FAM111B Polyclonal Antibody (Product # PA5-58474) shows weak to moderate nuclear positivity in the epithelial cells.
