Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [3]
- Flow cytometry [1]
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Validation data
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- Product number
- NBP2-47917-0.1mg - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal Moesin Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. Recognizes 78kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.
- Reactivity
- Human, Rat
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Moesin Antibody (MSN/493) - Azide and BSA Free [NBP2-47917] - Western Blot Analysis of human Jurkat cell lysate. Moesin Antibody (MSN/493).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Moesin Antibody (MSN/493) - Azide and BSA Free [NBP2-47917] - Human Testicular Carcinoma stained with Moesin Monoclonal Antibody (MSN/493)
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Moesin Antibody (MSN/493) - Azide and BSA Free [NBP2-47917] - Human Melanoma stained with Moesin Monoclonal Antibody (MSN/493)
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Moesin Antibody (MSN/493) - Azide and BSA Free [NBP2-47917] - Human Placenta stained with Moesin Monoclonal Antibody (MSN/493)
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: Moesin Antibody (MSN/493) - Azide and BSA Free [NBP2-47917] - Flow Cytometric Analysis of paraformaldehyde-fixed K562 cells. Moesin Antibody (MSN/493) followed by goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red)