Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 12134-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12134-2-AP, RRID:AB_2212191
- Product name
- UBE2C antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated UBE2C antibody (Cat. #12134-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The transcription factor NF-YA is crucial for neural progenitor maintenance during brain development.
Single-cell RNA profiling reveals classification and characteristics of mononuclear phagocytes in colorectal cancer.
Expression significance of Emi1, UBCH10 and CyclinB1 in esophageal squamous cell carcinoma.
Bioinformatics-based screening of key genes for transformation of tyrosine kinase inhibitor-resistant lung adenocarcinoma to small cell lung cancer.
UBE2C promotes malignancy of cutaneous squamous cell carcinoma.
Proteomic analysis reveals zinc-finger CCHC-type containing protein 3 as a factor inhibiting virus infection by promoting innate signaling.
Overexpression of Ubiquitin-Conjugating Enzyme E2C Is Associated with Worsened Prognosis in Prostate Cancer.
Identifying the Key Genes in Mouse Liver Regeneration After Partial Hepatectomy by Bioinformatics Analysis and in vitro/vivo Experiments.
Affinity-based protein profiling to reveal targets of puerarin involved in its protective effect on cardiomyocytes.
DNA primase subunit 1 deteriorated progression of hepatocellular carcinoma by activating AKT/mTOR signaling and UBE2C-mediated P53 ubiquitination.
SINAT E3 Ubiquitin Ligases Mediate FREE1 and VPS23A Degradation to Modulate Abscisic Acid Signaling.
Disturbed Flow Increases UBE2C (Ubiquitin E2 Ligase C) via Loss of miR-483-3p, Inducing Aortic Valve Calcification by the pVHL (von Hippel-Lindau Protein) and HIF-1α (Hypoxia-Inducible Factor-1α) Pathway in Endothelial Cells.
UBE2C functions as a potential oncogene by enhancing cell proliferation, migration, invasion, and drug resistance in hepatocellular carcinoma cells.
RIZ1 negatively regulates ubiquitin-conjugating enzyme E2C/UbcH10 via targeting c-Myc in meningioma.
Yamanaka T, Kurosawa M, Yoshida A, Shimogori T, Hiyama A, Maity SN, Hattori N, Matsui H, Nukina N
The Journal of biological chemistry 2024 Feb;300(2):105629
The Journal of biological chemistry 2024 Feb;300(2):105629
Single-cell RNA profiling reveals classification and characteristics of mononuclear phagocytes in colorectal cancer.
Ji T, Fu H, Wang L, Chen J, Tian S, Wang G, Wang L, Wang Z
PLoS genetics 2024 Feb;20(2):e1011176
PLoS genetics 2024 Feb;20(2):e1011176
Expression significance of Emi1, UBCH10 and CyclinB1 in esophageal squamous cell carcinoma.
Li H, Yang C, Chen K, Sun M
Pathology oncology research : POR 2023;29:1611081
Pathology oncology research : POR 2023;29:1611081
Bioinformatics-based screening of key genes for transformation of tyrosine kinase inhibitor-resistant lung adenocarcinoma to small cell lung cancer.
Zhang Y, Chen Q, Huang T, Zhu D, Lu Y
Frontiers in medicine 2023;10:1203461
Frontiers in medicine 2023;10:1203461
UBE2C promotes malignancy of cutaneous squamous cell carcinoma.
Luo R, Bai R, Guo J, Xian N, Zheng Y
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2023 Nov;29(11):e13526
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2023 Nov;29(11):e13526
Proteomic analysis reveals zinc-finger CCHC-type containing protein 3 as a factor inhibiting virus infection by promoting innate signaling.
Chen X, Li Z, Wang S, Tong G, Chen K, Zhao Y
Virus research 2022 Oct 2;319:198876
Virus research 2022 Oct 2;319:198876
Overexpression of Ubiquitin-Conjugating Enzyme E2C Is Associated with Worsened Prognosis in Prostate Cancer.
Wu X, Long X, Ma C, Cheuk YC, Hu M, Hu J, Jiang H
International journal of molecular sciences 2022 Nov 10;23(22)
International journal of molecular sciences 2022 Nov 10;23(22)
Identifying the Key Genes in Mouse Liver Regeneration After Partial Hepatectomy by Bioinformatics Analysis and in vitro/vivo Experiments.
Zhao J, Yu SZ, Cai Q, Ma D, Jiang L, Yang LP, Yu ZY
Frontiers in genetics 2021;12:670706
Frontiers in genetics 2021;12:670706
Affinity-based protein profiling to reveal targets of puerarin involved in its protective effect on cardiomyocytes.
Huang S, Wang FJ, Lin H, Liu T, Zhao CX, Chen LG
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111160
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111160
DNA primase subunit 1 deteriorated progression of hepatocellular carcinoma by activating AKT/mTOR signaling and UBE2C-mediated P53 ubiquitination.
Zhu M, Wu M, Bian S, Song Q, Xiao M, Huang H, You L, Zhang J, Zhang J, Cheng C, Ni W, Zheng W
Cell & bioscience 2021 Feb 23;11(1):42
Cell & bioscience 2021 Feb 23;11(1):42
SINAT E3 Ubiquitin Ligases Mediate FREE1 and VPS23A Degradation to Modulate Abscisic Acid Signaling.
Xia FN, Zeng B, Liu HS, Qi H, Xie LJ, Yu LJ, Chen QF, Li JF, Chen YQ, Jiang L, Xiao S
The Plant cell 2020 Oct;32(10):3290-3310
The Plant cell 2020 Oct;32(10):3290-3310
Disturbed Flow Increases UBE2C (Ubiquitin E2 Ligase C) via Loss of miR-483-3p, Inducing Aortic Valve Calcification by the pVHL (von Hippel-Lindau Protein) and HIF-1α (Hypoxia-Inducible Factor-1α) Pathway in Endothelial Cells.
Fernandez Esmerats J, Villa-Roel N, Kumar S, Gu L, Salim MT, Ohh M, Taylor WR, Nerem RM, Yoganathan AP, Jo H
Arteriosclerosis, thrombosis, and vascular biology 2019 Mar;39(3):467-481
Arteriosclerosis, thrombosis, and vascular biology 2019 Mar;39(3):467-481
UBE2C functions as a potential oncogene by enhancing cell proliferation, migration, invasion, and drug resistance in hepatocellular carcinoma cells.
Xiong Y, Lu J, Fang Q, Lu Y, Xie C, Wu H, Yin Z
Bioscience reports 2019 Apr 30;39(4)
Bioscience reports 2019 Apr 30;39(4)
RIZ1 negatively regulates ubiquitin-conjugating enzyme E2C/UbcH10 via targeting c-Myc in meningioma.
Cai Z, Zou Y, Hu H, Lu C, Sun W, Jiang L, Hu G
American journal of translational research 2017;9(5):2645-2655
American journal of translational research 2017;9(5):2645-2655
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 12134-2-AP(UBE2C antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The UBE2C antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human UBE2C. This antibody recognizes human,mouse,rat antigen. The UBE2C antibody has been validated for the following applications: ELISA, WB, IHC analysis.