Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
Reference
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- Product number
- 66087-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#66087-1-Ig, RRID:AB_11232220
- Product name
- UBE2C antibody
- Antibody type
- Monoclonal
- Description
- UBE2C antibody (Cat. #66087-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1C12H8
- Vial size
- 20ul, 150ul
Submitted references UBE2C orchestrates bone formation through stabilization of SMAD1/5.
Shared and distinct mechanisms of UBA1 inactivation across different diseases.
Distinctive multicellular immunosuppressive hubs confer different intervention strategies for left- and right-sided colon cancers.
Shared and Distinct Mechanisms of UBA1 Inactivation Across Different Diseases.
Ubiquitin-specific peptidase 14 maintains estrogen receptor α stability via its deubiquitination activity in endometrial cancer.
LINC01194 recruits NUMA1 to promote ubiquitination of RYR2 to enhance malignant progression in triple-negative breast cancer.
N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells.
PRPF6 promotes androgen receptor/androgen receptor-variant 7 actions in castration-resistant prostate cancer cells.
Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition.
Silencing ubiquitin-conjugating enzyme 2C inhibits proliferation and epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma.
Zhang H, Du Y, Lu D, Wang X, Li Y, Qing J, Zhang Y, Liu H, Lv L, Zhang X, Liu Y, Zhou Y, Zhang P
Bone 2024 Oct;187:117175
Bone 2024 Oct;187:117175
Shared and distinct mechanisms of UBA1 inactivation across different diseases.
Collins JC, Magaziner SJ, English M, Hassan B, Chen X, Balanda N, Anderson M, Lam A, Fernandez-Pol S, Kwong B, Greenberg PL, Terrier B, Likhite ME, Kosmider O, Wang Y, Samara NL, Walters KJ, Beck DB, Werner A
The EMBO journal 2024 May;43(10):1919-1946
The EMBO journal 2024 May;43(10):1919-1946
Distinctive multicellular immunosuppressive hubs confer different intervention strategies for left- and right-sided colon cancers.
Liu B, Li S, Cheng Y, Song P, Xu M, Li Z, Shao W, Xin J, Fu Z, Gu D, Du M, Zhang Z, Wang M
Cell reports. Medicine 2024 Jun 18;5(6):101589
Cell reports. Medicine 2024 Jun 18;5(6):101589
Shared and Distinct Mechanisms of UBA1 Inactivation Across Different Diseases.
Collins JC, Magaziner SJ, English M, Hassan B, Chen X, Balanda N, Anderson M, Lam A, Fernandez-Pol S, Kwong B, Greenberg PL, Terrier B, Likhite ME, Kosmider O, Wang Y, Samara NL, Walters KJ, Beck DB, Werner A
bioRxiv : the preprint server for biology 2023 Oct 10;
bioRxiv : the preprint server for biology 2023 Oct 10;
Ubiquitin-specific peptidase 14 maintains estrogen receptor α stability via its deubiquitination activity in endometrial cancer.
Su Y, Zeng K, Liu S, Wu Y, Wang C, Wang S, Lin L, Zou R, Sun G, Luan R, Zhou B, Bai Y, Niu J, Zhang Y, Zhao Y
The Journal of biological chemistry 2023 Jan;299(1):102734
The Journal of biological chemistry 2023 Jan;299(1):102734
LINC01194 recruits NUMA1 to promote ubiquitination of RYR2 to enhance malignant progression in triple-negative breast cancer.
Zhai D, Zhang M, Li Y, Bi J, Kuang X, Shan Z, Shao N, Lin Y
Cancer letters 2022 Sep 28;544:215797
Cancer letters 2022 Sep 28;544:215797
N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells.
Wang R, Wen P, Yang G, Feng Y, Mi Y, Wang X, Zhu S, Chen YQ
Cell death & disease 2022 Jul 19;13(7):626
Cell death & disease 2022 Jul 19;13(7):626
PRPF6 promotes androgen receptor/androgen receptor-variant 7 actions in castration-resistant prostate cancer cells.
Liu W, Wang C, Wang S, Zeng K, Wei S, Sun N, Sun G, Wang M, Zou R, Liu W, Lin L, Song H, Jin Z, Zhao Y
International journal of biological sciences 2021;17(1):188-203
International journal of biological sciences 2021;17(1):188-203
Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition.
Hong AL, Tseng YY, Wala JA, Kim WJ, Kynnap BD, Doshi MB, Kugener G, Sandoval GJ, Howard TP, Li J, Yang X, Tillgren M, Ghandi M, Sayeed A, Deasy R, Ward A, McSteen B, Labella KM, Keskula P, Tracy A, Connor C, Clinton CM, Church AJ, Crompton BD, Janeway KA, Van Hare B, Sandak D, Gjoerup O, Bandopadhayay P, Clemons PA, Schreiber SL, Root DE, Gokhale PC, Chi SN, Mullen EA, Roberts CW, Kadoch C, Beroukhim R, Ligon KL, Boehm JS, Hahn WC
eLife 2019 Mar 12;8
eLife 2019 Mar 12;8
Silencing ubiquitin-conjugating enzyme 2C inhibits proliferation and epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma.
Wang X, Yin L, Yang L, Zheng Y, Liu S, Yang J, Cui H, Wang H
The FEBS journal 2019 Dec;286(24):4889-4909
The FEBS journal 2019 Dec;286(24):4889-4909
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 66087-1-Ig( UBE2C Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using UBE2C antibody 66087-1-lg at 1:25 dilution and Rhodamine-labeled goat anti-mouse IgG (red).
- Sample type
- cell line