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- Antigen structure
- References [16]
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- Western blot [1]
- Immunoprecipitation [1]
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- Product number
- 11096-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11096-1-AP, RRID:AB_2158220
- Product name
- OSBP antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated OSBP antibody (Cat. #11096-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Multi-Omics after O-GlcNAc Alteration Identifies Cellular Processes Working Synergistically to Promote Aneuploidy.
Elucidation of OSW-1-Induced Stress Responses in Neuro2a Cells.
The CH24H metabolite, 24HC, blocks viral entry by disrupting intracellular cholesterol homeostasis.
A phosphoinositide signalling pathway mediates rapid lysosomal repair.
A Proximity biotinylation assay with a host protein bait reveals multiple factors modulating enterovirus replication.
A Small Molecule, 4-Phenylbutyric Acid, Suppresses HCV Replication via Epigenetically Induced Hepatic Hepcidin.
Nir2 Is an Effector of VAPs Necessary for Efficient Hepatitis C Virus Replication and Phosphatidylinositol 4-Phosphate Enrichment at the Viral Replication Organelle.
Molecular partners of hNOT/ALG3, the human counterpart of the Drosophila NOT and yeast ALG3 gene, suggest its involvement in distinct cellular processes relevant to congenital disorders of glycosylation, cancer, neurodegeneration and a variety of further pathologies.
Cadmium induced redistribution of cholesterol by upregulating ABCA1 and downregulating OSBP.
Modulation of the Host Lipid Landscape to Promote RNA Virus Replication: The Picornavirus Encephalomyocarditis Virus Converges on the Pathway Used by Hepatitis C Virus.
CARTS biogenesis requires VAP-lipid transfer protein complexes functioning at the endoplasmic reticulum-Golgi interface.
Oxysterol-binding protein is a phosphatidylinositol 4-kinase effector required for HCV replication membrane integrity and cholesterol trafficking.
The antiviral effector IFITM3 disrupts intracellular cholesterol homeostasis to block viral entry.
Oxysterol-binding protein (OSBP) enhances replication of intracellular Salmonella and binds the Salmonella SPI-2 effector SseL via its N-terminus.
STARD4 knockdown in HepG2 cells disrupts cholesterol trafficking associated with the plasma membrane, ER, and ERC.
Regulation of oxysterol-binding protein Golgi localization through protein kinase D-mediated phosphorylation.
Boyd SS, Robarts DR, Nguyen K, Villar M, Alghusen I, Kotulkar M, Denson A, Fedosyuk H, Whelan SA, Lee NCY, Hanover J, Dias WB, Tan EP, McGreal SR, Artigues A, Swerdlow RH, Thompson JA, Apte U, Slawson C
bioRxiv : the preprint server for biology 2024 Apr 16;
bioRxiv : the preprint server for biology 2024 Apr 16;
Elucidation of OSW-1-Induced Stress Responses in Neuro2a Cells.
Oh-Hashi K, Nakamura H, Ogawa H, Hirata Y, Sakurai K
International journal of molecular sciences 2023 Mar 17;24(6)
International journal of molecular sciences 2023 Mar 17;24(6)
The CH24H metabolite, 24HC, blocks viral entry by disrupting intracellular cholesterol homeostasis.
Yuan Y, Fang A, Wang Z, Wang Z, Sui B, Zhu Y, Zhang Y, Wang C, Zhang R, Zhou M, Chen H, Fu ZF, Zhao L
Redox biology 2023 Aug;64:102769
Redox biology 2023 Aug;64:102769
A phosphoinositide signalling pathway mediates rapid lysosomal repair.
Tan JX, Finkel T
Nature 2022 Sep;609(7928):815-821
Nature 2022 Sep;609(7928):815-821
A Proximity biotinylation assay with a host protein bait reveals multiple factors modulating enterovirus replication.
Moghimi S, Viktorova EG, Gabaglio S, Zimina A, Budnik B, Wynn BG, Sztul E, Belov GA
PLoS pathogens 2022 Oct;18(10):e1010906
PLoS pathogens 2022 Oct;18(10):e1010906
A Small Molecule, 4-Phenylbutyric Acid, Suppresses HCV Replication via Epigenetically Induced Hepatic Hepcidin.
Kim K, Lee YS, Jeong S, Kim D, Chon S, Pak YK, Kim S, Ha J, Kang I, Choe W
International journal of molecular sciences 2020 Aug 1;21(15)
International journal of molecular sciences 2020 Aug 1;21(15)
Nir2 Is an Effector of VAPs Necessary for Efficient Hepatitis C Virus Replication and Phosphatidylinositol 4-Phosphate Enrichment at the Viral Replication Organelle.
Wang H, Tai AW
Journal of virology 2019 Nov 15;93(22)
Journal of virology 2019 Nov 15;93(22)
Molecular partners of hNOT/ALG3, the human counterpart of the Drosophila NOT and yeast ALG3 gene, suggest its involvement in distinct cellular processes relevant to congenital disorders of glycosylation, cancer, neurodegeneration and a variety of further pathologies.
Hacker B, Schultheiß C, Döring M, Kurzik-Dumke U
Human molecular genetics 2018 Jun 1;27(11):1858-1878
Human molecular genetics 2018 Jun 1;27(11):1858-1878
Cadmium induced redistribution of cholesterol by upregulating ABCA1 and downregulating OSBP.
Wang Y, Ji X, Dai S, Liu H, Yan D, Zhou Y, Gu J, Shi H
Journal of inorganic biochemistry 2018 Dec;189:199-207
Journal of inorganic biochemistry 2018 Dec;189:199-207
Modulation of the Host Lipid Landscape to Promote RNA Virus Replication: The Picornavirus Encephalomyocarditis Virus Converges on the Pathway Used by Hepatitis C Virus.
Dorobantu CM, Albulescu L, Harak C, Feng Q, van Kampen M, Strating JR, Gorbalenya AE, Lohmann V, van der Schaar HM, van Kuppeveld FJ
PLoS pathogens 2015 Sep;11(9):e1005185
PLoS pathogens 2015 Sep;11(9):e1005185
CARTS biogenesis requires VAP-lipid transfer protein complexes functioning at the endoplasmic reticulum-Golgi interface.
Wakana Y, Kotake R, Oyama N, Murate M, Kobayashi T, Arasaki K, Inoue H, Tagaya M
Molecular biology of the cell 2015 Dec 15;26(25):4686-99
Molecular biology of the cell 2015 Dec 15;26(25):4686-99
Oxysterol-binding protein is a phosphatidylinositol 4-kinase effector required for HCV replication membrane integrity and cholesterol trafficking.
Wang H, Perry JW, Lauring AS, Neddermann P, De Francesco R, Tai AW
Gastroenterology 2014 May;146(5):1373-85.e1-11
Gastroenterology 2014 May;146(5):1373-85.e1-11
The antiviral effector IFITM3 disrupts intracellular cholesterol homeostasis to block viral entry.
Amini-Bavil-Olyaee S, Choi YJ, Lee JH, Shi M, Huang IC, Farzan M, Jung JU
Cell host & microbe 2013 Apr 17;13(4):452-64
Cell host & microbe 2013 Apr 17;13(4):452-64
Oxysterol-binding protein (OSBP) enhances replication of intracellular Salmonella and binds the Salmonella SPI-2 effector SseL via its N-terminus.
Auweter SD, Yu HB, Arena ET, Guttman JA, Finlay BB
Microbes and infection 2012 Feb;14(2):148-54
Microbes and infection 2012 Feb;14(2):148-54
STARD4 knockdown in HepG2 cells disrupts cholesterol trafficking associated with the plasma membrane, ER, and ERC.
Garbarino J, Pan M, Chin HF, Lund FW, Maxfield FR, Breslow JL
Journal of lipid research 2012 Dec;53(12):2716-25
Journal of lipid research 2012 Dec;53(12):2716-25
Regulation of oxysterol-binding protein Golgi localization through protein kinase D-mediated phosphorylation.
Nhek S, Ngo M, Yang X, Ng MM, Field SJ, Asara JM, Ridgway ND, Toker A
Molecular biology of the cell 2010 Jul 1;21(13):2327-37
Molecular biology of the cell 2010 Jul 1;21(13):2327-37
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 11096-1-AP(OSBP antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP result of anti-OSBP(11096-1-AP for IP and Detection).
- Sample type
- cell line
