634501

PDCD6IP antibody from BioLegend
AIP1, Alix, Hp95
Western blot
Supportive data in Antibodypedia
Immunocytochemistry
Recommended by provider
Immunoprecipitation
Recommended by provider

Antibody data

Product number
634501
Provider
BioLegend
Proper citation
BioLegend Cat#634501, RRID:AB_2268110
Product name
Purified anti-Alix
Provider product page
BioLegend - 634501
Antibody type
Monoclonal
Antigen
Recombinant full-length human Alix protein
Description
Alix (ALG-2-interacting protein X) is an adaptor protein that was first described for its capacity to bind to the calcium-binding protein ALG-2, the expression of which seemed necessary for cell death. Predicted molecular weight approximately 96 kD. Alix contains an N-terminal Bro1 domain and a C-terminal proline-rich domain (PRD). The PRD contains multiple polyproline motifs, which are potential docking sites for proteins containing SH3 domains, interact with multiple cellular Alix-binding partners that are involved in apoptotic induction, endosomal sorting, and endocytosis. Bro1 domain interacts with CHMP4b which is also involved in endosomal sorting.
Reactivity
Human, Mouse, Zebrafish
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C.
Provider Type Product Number
- No reagents -