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Learn55290-1-AP
antibody from Proteintech Group
Targeting: FBXW7
AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 55290-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- FBXW7 antibody
- Antibody type
- Polyclonal
- Description
- FBXW7 antibody (Cat. #55290-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CircNCX1 modulates cardiomyocyte proliferation through promoting ubiquitination of BRG1.
FBXO8 is a novel prognostic biomarker in different molecular subtypes of breast cancer and suppresses breast cancer progression by targeting c-MYC.
The interface targeting hnRNPA2B1 regulates the repression of transthyretin against human retinal microvascular endothelial cells in high-glucose environment.
RUNX3 inactivates oncogenic MYC through disruption of MYC/MAX complex and subsequent recruitment of GSK3β-FBXW7 cascade.
Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal.
Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication.
Demethylzeylasteral inhibits proliferation, migration, and invasion through FBXW7/c-Myc axis in gastric cancer.
The deubiquitinase USP38 promotes cell proliferation through stabilizing c-Myc.
E3 ligase Fbw7 participates in oxidative stress‑induced myocardial cell injury via interacting with Mcl‑1.
Inhibition of the prolyl isomerase Pin1 enhances the ability of sorafenib to induce cell death and inhibit tumor growth in hepatocellular carcinoma.
Sensitivity of non-small cell lung cancer to erlotinib is regulated by the Notch/miR-223/FBXW7 pathway.
Rictor Regulates Spermatogenesis by Controlling Sertoli Cell Cytoskeletal Organization and Cell Polarity in the Mouse Testis.
Yijian L, Weihan S, Lin Y, Heng Z, Yu W, Lin S, Shuo M, Mengyang L, Jianxun W
Cellular signalling 2024 Aug;120:111193
Cellular signalling 2024 Aug;120:111193
FBXO8 is a novel prognostic biomarker in different molecular subtypes of breast cancer and suppresses breast cancer progression by targeting c-MYC.
Khan AJ, Man S, Abbas M, Liu S, Zhang F
Biochimica et biophysica acta. General subjects 2024 Apr;1868(4):130577
Biochimica et biophysica acta. General subjects 2024 Apr;1868(4):130577
The interface targeting hnRNPA2B1 regulates the repression of transthyretin against human retinal microvascular endothelial cells in high-glucose environment.
Tian Y, Ye L, Shao J, Xin Y
Diabetic medicine : a journal of the British Diabetic Association 2023 Sep;40(9):e15125
Diabetic medicine : a journal of the British Diabetic Association 2023 Sep;40(9):e15125
RUNX3 inactivates oncogenic MYC through disruption of MYC/MAX complex and subsequent recruitment of GSK3β-FBXW7 cascade.
Oei V, Chuang LSH, Matsuo J, Srivastava S, Teh M, Ito Y
Communications biology 2023 Jul 3;6(1):689
Communications biology 2023 Jul 3;6(1):689
Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal.
Yeh DW, Liu C, Hernandez JC, Tahara SM, Tsukamoto H, Machida K
iScience 2023 Jul 21;26(7):107035
iScience 2023 Jul 21;26(7):107035
Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication.
Zeng J, Hills SA, Ozono E, Diffley JFX
Cell 2023 Feb 2;186(3):528-542.e14
Cell 2023 Feb 2;186(3):528-542.e14
Demethylzeylasteral inhibits proliferation, migration, and invasion through FBXW7/c-Myc axis in gastric cancer.
Li Y, Su Y, Zhao Y, Hu X, Zhao G, He J, Wan S, Lü M, Cui H
MedComm 2021 Sep;2(3):467-480
MedComm 2021 Sep;2(3):467-480
The deubiquitinase USP38 promotes cell proliferation through stabilizing c-Myc.
Xu Z, Hu H, Fang D, Wang J, Zhao K
The international journal of biochemistry & cell biology 2021 Aug;137:106023
The international journal of biochemistry & cell biology 2021 Aug;137:106023
E3 ligase Fbw7 participates in oxidative stress‑induced myocardial cell injury via interacting with Mcl‑1.
Li X, Zhang N, Zhang Y, Jia P, Guo Y, Tian Y, You S, Wu S, Sun Y
Molecular medicine reports 2019 Aug;20(2):1561-1568
Molecular medicine reports 2019 Aug;20(2):1561-1568
Inhibition of the prolyl isomerase Pin1 enhances the ability of sorafenib to induce cell death and inhibit tumor growth in hepatocellular carcinoma.
Zheng M, Xu H, Liao XH, Chen CP, Zhang AL, Lu W, Wang L, Yang D, Wang J, Liu H, Zhou XZ, Lu KP
Oncotarget 2017 May 2;8(18):29771-29784
Oncotarget 2017 May 2;8(18):29771-29784
Sensitivity of non-small cell lung cancer to erlotinib is regulated by the Notch/miR-223/FBXW7 pathway.
Zhang H, Chen F, He Y, Yi L, Ge C, Shi X, Tang C, Wang D, Wu Y, Nian W
Bioscience reports 2017 Jun 30;37(3)
Bioscience reports 2017 Jun 30;37(3)
Rictor Regulates Spermatogenesis by Controlling Sertoli Cell Cytoskeletal Organization and Cell Polarity in the Mouse Testis.
Dong H, Chen Z, Wang C, Xiong Z, Zhao W, Jia C, Lin J, Lin Y, Yuan W, Zhao AZ, Bai X
Endocrinology 2015 Nov;156(11):4244-56
Endocrinology 2015 Nov;156(11):4244-56
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 55290-1-AP(FBXW7 antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FBXW7 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human FBXW7. This antibody recognizes human, mouse antigen. The FBXW7 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
