15938-1-AP

antibody from Proteintech Group

Targeting: CNOT10 FLJ12890, FLJ13165

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

15938-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#15938-1-AP, RRID:AB_2229678

Product name

CNOT10 antibody

Antibody type

Polyclonal

Description

CNOT10 antibody (Cat. #15938-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation.

Yiu SPT, Zerbe C, Vanderwall D, Huttlin EL, Weekes MP, Gewurz BE
Molecular cell 2023 Jul 6;83(13):2367-2386.e15

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The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.

Mauxion F, Basquin J, Ozgur S, Rame M, Albrecht J, Schäfer I, Séraphin B, Conti E
Cell reports 2023 Jan 31;42(1):111902

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Control of immediate early gene expression by CPEB4-repressor complex-mediated mRNA degradation.

Poetz F, Lebedeva S, Schott J, Lindner D, Ohler U, Stoecklin G
Genome biology 2022 Sep 12;23(1):193

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ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.

Zhang T, Sun L, Hao Y, Suo C, Shen S, Wei H, Ma W, Zhang P, Wang T, Gu X, Li ST, Chen Z, Yan R, Zhang Y, Cai Y, Zhou R, Jia W, Huang F, Gao P, Zhang H
Nature cancer 2022 Jan;3(1):75-89

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RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation.

Poetz F, Corbo J, Levdansky Y, Spiegelhalter A, Lindner D, Magg V, Lebedeva S, Schweiggert J, Schott J, Valkov E, Stoecklin G
Nature communications 2021 Dec 9;12(1):7175

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Alternative splicing of CNOT7 diversifies CCR4-NOT functions.

Chapat C, Chettab K, Simonet P, Wang P, De La Grange P, Le Romancer M, Corbo L
Nucleic acids research 2017 Aug 21;45(14):8508-8523

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Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs.

Färber V, Erben E, Sharma S, Stoecklin G, Clayton C
Nucleic acids research 2013 Jan;41(2):1211-22

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C2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complex.

Mauxion F, Prève B, Séraphin B
RNA biology 2013 Feb;10(2):267-76

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

human brain tissue were subjected to SDS PAGE followed by western blot with 15938-1-AP(CNOT10 antibody) at dilution of 1:500

Sample type

tissue

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of HepG2 cells, using CNOT10 antibody 15938-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human colon cancer using 15938-1-AP(CNOT10 antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human colon cancer using 15938-1-AP(CNOT10 antibody) at dilution of 1:50 (under 40x lens)

Sample type

tissue