orb2635073

antibody from Biorbyt
Targeting: CNOT10 FLJ12890, FLJ13165
Provider product page for orb2635073
Western blot
ELISA
Immunocytochemistry
Flow cytometry

Antibody data

Product number
orb2635073 - Provider product page
Provider
Biorbyt
Product name
CNOT10 Antibody / CCR4-NOT transcription complex subunit 10
Antibody type
Monoclonal
Description
CNOT10 is a subunit of the CCR4-NOT complex which consists of at least five other CNOT subunit proteins and TAB182. The CCR4-NOT complex is an evolutionarily conserved, multi-component complex known to be involved in transcription, as well as in mRNA degradation. Various subunits (e.g. CNOT1, CNOT3) are uniquely involved in influencing nuclear hormone receptor activities. In effect, this complex has an important role as a transcription regulator and repressor of nuclear receptor signaling that is relevant to the molecular pathways involved in cancer. The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
PCRP-CNOT10-1D5
Vial size
20 ug
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
CNOT10 protein structure - orb2635073 shown in red.