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- Antigen structure
- References [15]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 11399-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11399-1-AP, RRID:AB_10699868
- Product name
- NMNAT1 antibody
- Antibody type
- Polyclonal
- Description
- NMNAT1 antibody (Cat. #11399-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, pig and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Porcine
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NMNAT1 Activates Autophagy to Delay D-Galactose-Induced Aging in Cochlear Hair Cells.
Prognostic and Immunological Significance of NMNAT1 in Colorectal and Pan-Cancer Contexts.
Nicotinamide metabolic dysregulation plays a key role in Benzo[a]pyrene-induced adverse birth outcomes: Evidence from multi-omics profiling, experimental and epidemiological validation.
Mitochondrial NAD(+) deficiency in vascular smooth muscle impairs collagen III turnover to trigger thoracic and abdominal aortic aneurysm.
A Novel FNDC1-NAMPT-NAD axis is Implicated in Small and Large-vessel Arterial Disease and Drives Vascular Calcification.
Quantitative dynamics of intracellular NMN by genetically encoded biosensor.
β-Nicotinamide mononucleotide alleviates Alcohol-Induced liver injury in a mouse model through activation of NAD(+)/SIRT1 signaling pathways.
β-Nicotinamide mononucleotide supplementation prolongs the lifespan of prematurely aged mice and protects colon function in ageing mice.
Nmnat1 Deficiency Causes Mitoribosome Excess in Diabetic Nephropathy Mediated by Transcriptional Repressor HIC1.
NAD(+) supplementation improves mitochondrial functions and normalizes glaucomatous trabecular meshwork features.
Control of NAD(+) homeostasis by autophagic flux modulates mitochondrial and cardiac function.
Nicotinamide mononucleotide ameliorates adriamycin-induced renal damage by epigenetically suppressing the NMN/NAD consumers mediated by Twist2.
Reduced Nicotinamide Mononucleotide (NMNH) Potently Enhances NAD(+) and Suppresses Glycolysis, the TCA Cycle, and Cell Growth.
Pre-emptive Short-term Nicotinamide Mononucleotide Treatment in a Mouse Model of Diabetic Nephropathy.
Hyperglycemia-reduced NAD(+) biosynthesis impairs corneal epithelial wound healing in diabetic mice.
Wei Y, Yang W, Wu H, Kong M, Fan D, Zhang Y, Cheng N, Du J, Guo L, Li Y, Zhang Y, Dai Q, Cao W, Yang J, Fang Q
Aging cell 2026 Feb;25(2):e70373
Aging cell 2026 Feb;25(2):e70373
Prognostic and Immunological Significance of NMNAT1 in Colorectal and Pan-Cancer Contexts.
Wen L, Wang P, Zhang G, Ma Y, Li J, Chen D, Liu L, Hu H, Huang C, Yao X
OncoTargets and therapy 2025;18:389-410
OncoTargets and therapy 2025;18:389-410
Nicotinamide metabolic dysregulation plays a key role in Benzo[a]pyrene-induced adverse birth outcomes: Evidence from multi-omics profiling, experimental and epidemiological validation.
Zhao N, Song W, Sun T, Wu W, Feng Y, Ma N, Wang S
Journal of hazardous materials 2025 Sep 28;498:140000
Journal of hazardous materials 2025 Sep 28;498:140000
Mitochondrial NAD(+) deficiency in vascular smooth muscle impairs collagen III turnover to trigger thoracic and abdominal aortic aneurysm.
Zhang J, Tang Y, Zhang S, Xie Z, Ma W, Liu S, Fang Y, Zheng S, Huang C, Yan G, Abudupataer M, Xin Y, Zhu J, Han W, Wang W, Shen F, Lai H, Liu Y, Ye D, Yu FX, Xu Y, Pan C, Wang C, Zhu K, Zhang W
Nature cardiovascular research 2025 Mar;4(3):275-292
Nature cardiovascular research 2025 Mar;4(3):275-292
A Novel FNDC1-NAMPT-NAD axis is Implicated in Small and Large-vessel Arterial Disease and Drives Vascular Calcification.
Lee S, Guo Y, Kajuluri LP, Roh K, Singh K, Jiang W, Moore E, Tattersfield H, Ostrom K, Birchenough C, Johnson AL, Krinsky S, Bouchouari H, Mohammedeh M, Lee LY, Wyant GA, Rich SS, Rotter JL, Taylor KD, Malik S, Gerszten R, Cruz D, Tracy RP, Wu H, Zhang H, Lu H, Kavousi M, Shanahan C, Duer M, Kramann R, Nazarian RM, Eagleton MJ, Chen Y, Miller CL, Nigwekar SU, Malhotra R
bioRxiv : the preprint server for biology 2025 Jul 10;
bioRxiv : the preprint server for biology 2025 Jul 10;
Quantitative dynamics of intracellular NMN by genetically encoded biosensor.
Chen L, Wang P, Huang G, Cheng W, Liu K, Yu Q
Biosensors & bioelectronics 2025 Jan 1;267:116842
Biosensors & bioelectronics 2025 Jan 1;267:116842
β-Nicotinamide mononucleotide alleviates Alcohol-Induced liver injury in a mouse model through activation of NAD(+)/SIRT1 signaling pathways.
Yang X, Zheng E, Lin Y, Sun H, Zhang J, Yu Y
Hereditas 2025 Aug 16;162(1):161
Hereditas 2025 Aug 16;162(1):161
β-Nicotinamide mononucleotide supplementation prolongs the lifespan of prematurely aged mice and protects colon function in ageing mice.
Gu Y, Gao L, He J, Luo M, Hu M, Lin Y, Li J, Hou T, Si J, Yu Y
Food & function 2024 Mar 18;15(6):3199-3213
Food & function 2024 Mar 18;15(6):3199-3213
Nmnat1 Deficiency Causes Mitoribosome Excess in Diabetic Nephropathy Mediated by Transcriptional Repressor HIC1.
Hasegawa K, Tamaki M, Sakamaki Y, Wakino S
International journal of molecular sciences 2024 Jun 9;25(12)
International journal of molecular sciences 2024 Jun 9;25(12)
NAD(+) supplementation improves mitochondrial functions and normalizes glaucomatous trabecular meshwork features.
Liu Y, Bu Q, Hu D, Chen C, Zhu J, Zhou Q, Li Z, Pan X
Experimental cell research 2024 Jul 1;440(1):114137
Experimental cell research 2024 Jul 1;440(1):114137
Control of NAD(+) homeostasis by autophagic flux modulates mitochondrial and cardiac function.
Zhang Q, Li Z, Li Q, Trammell SA, Schmidt MS, Pires KM, Cai J, Zhang Y, Kenny H, Boudina S, Brenner C, Abel ED
The EMBO journal 2024 Feb;43(3):362-390
The EMBO journal 2024 Feb;43(3):362-390
Nicotinamide mononucleotide ameliorates adriamycin-induced renal damage by epigenetically suppressing the NMN/NAD consumers mediated by Twist2.
Hasegawa K, Sakamaki Y, Tamaki M, Wakino S
Scientific reports 2022 Aug 12;12(1):13712
Scientific reports 2022 Aug 12;12(1):13712
Reduced Nicotinamide Mononucleotide (NMNH) Potently Enhances NAD(+) and Suppresses Glycolysis, the TCA Cycle, and Cell Growth.
Liu Y, Luo C, Li T, Zhang W, Zong Z, Liu X, Deng H
Journal of proteome research 2021 May 7;20(5):2596-2606
Journal of proteome research 2021 May 7;20(5):2596-2606
Pre-emptive Short-term Nicotinamide Mononucleotide Treatment in a Mouse Model of Diabetic Nephropathy.
Yasuda I, Hasegawa K, Sakamaki Y, Muraoka H, Kawaguchi T, Kusahana E, Ono T, Kanda T, Tokuyama H, Wakino S, Itoh H
Journal of the American Society of Nephrology : JASN 2021 Jun 1;32(6):1355-1370
Journal of the American Society of Nephrology : JASN 2021 Jun 1;32(6):1355-1370
Hyperglycemia-reduced NAD(+) biosynthesis impairs corneal epithelial wound healing in diabetic mice.
Li Y, Li J, Zhao C, Yang L, Qi X, Wang X, Zhou Q, Shi W
Metabolism: clinical and experimental 2021 Jan;114:154402
Metabolism: clinical and experimental 2021 Jan;114:154402
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human testis tissue were subjected to SDS PAGE followed by western blot with 11399-1-AP(NMNAT1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NMNAT1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NMNAT1. This antibody recognizes human antigen. The NMNAT1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
