11808-1-AP

antibody from Proteintech Group

Targeting: RAB10

Provider product page for 11808-1-AP

Western blot

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [30]
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Validations
Western blot [1]
Immunohistochemistry [1]

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Product number: 11808-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#11808-1-AP, RRID:AB_2173442
Product name: RAB10 antibody
Antibody type: Polyclonal
Description: KD/KO validated RAB10 antibody (Cat. #11808-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, Canine and has been validated for the following applications: IHC, WB,ELISA.
Reactivity: Human, Mouse, Rat, Canine
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

RAB10 protein structure - 11808-1-AP shown in red.

Submitted references Dihydroartemisinin requires NR1D1 mediated Rab7 ubiquitination to regulate hepatic stellate cells lipophagy in liver fibrosis.

Bao Z, Xu M, Kan Y, Guo X, Li M, Wang J, Zhou Y, Zhang Z, Shao J, Zhang F, Chen L, Zheng S, Xuan J
International journal of biological macromolecules 2025 May;305(Pt 1):141055

Identification of a novel FOXO3‑associated prognostic model in hepatocellular carcinoma.

Guan S, Lin Q, Huang P, Lin K, Duan S
Oncology letters 2025 May;29(5):230

Rab10 plays a protective role in the development of pathological cardiac hypertrophy.

Xu F, Wu M, Wang Y, Luo H, Gao X, Lai S, Lu C
Journal of molecular and cellular cardiology plus 2025 Dec;14:100494

Rab10 regulates neuropeptide release by maintaining Ca(2+) homeostasis and protein synthesis.

Dong J, Chen M, van Weering JRT, Domínguez N, Li KW, Smit AB, Toonen RF, Verhage M
eLife 2025 Apr 2;13

Quantitative proteomic analysis using a mouse model of Lewy body dementia induced by α-synuclein preformed fibrils injection.

Akkentli F, Jang IK, Choi Y, Min Y, Park J, Jo H, Kim L, Mendpara A, Bains B, Yoo D, Xu J, Na CH, Kang SU
Frontiers in dementia 2024;3:1477986

Role of Rab10 in cocaine-induced behavioral effects is associated with GABAB receptor membrane expression in the nucleus accumbens.

Yu Z, Fu Q, Qiu T, Yang C, Lu M, Peng Q, Yang J, Hu Z
Frontiers in pharmacology 2024;15:1496657

Upregulation of Amy1 in the salivary glands of mice exposed to a lunar gravity environment using the multiple artificial gravity research system.

Ouchi T, Kono K, Satou R, Kurashima R, Yamaguchi K, Kimura M, Shibukawa Y
Frontiers in physiology 2024;15:1417719

A guide to selecting high-performing antibodies for Rab10 (UniProt ID: P61026) for use in western blot, immunoprecipitation, and immunofluorescence.

Ruíz Moleón V, Alende C, Fotouhi M, Southern K, Ayoubi R, Laflamme C, NeuroSGC/YCharOS/EDDU collaborative group, ABIF consortium
F1000Research 2024;13:1061

Stretch triggers microtubule stabilization and MARCKS-dependent membrane incorporation in the shaft of embryonic axons.

Sousa SC, Aroso M, Bessa R, Veríssimo E, Ferreira da Silva T, Lopes CDF, Brites P, Vieira J, Vieira CP, Aguiar PC, Sousa MM
Current biology : CB 2024 Oct 7;34(19):4577-4588.e8

RABIF promotes hepatocellular carcinoma progression through regulation of mitophagy and glycolysis.

Feng N, Zhang R, Wen X, Wang W, Zhang N, Zheng J, Zhang L, Liu N
Communications biology 2024 Oct 16;7(1):1333

Manganese disrupts the maturation and degradation of axonal autophagosome leading to hippocampal synaptic toxicity in mice via the activation of LRRK2 on phosphorylation of Rab10.

Ma Z, Liu K, Zhang RF, Xie ZX, Liu W, Xu B
The Science of the total environment 2024 Mar 10;915:170021

LncRNA136131 suppresses apoptosis of renal tubular epithelial cells in acute kidney injury by targeting the miR-378a-3p/Rab10 axis.

Wu Z, Pan J, Yang J, Zhang D
Aging 2022 Apr 28;14(8):3666-3686

Hsa_circ_001659 serves as a novel diagnostic and prognostic biomarker for colorectal cancer.

He B, Chao W, Huang Z, Zeng J, Yang J, Luo D, Huang S, Pan H, Hao Y
Biochemical and biophysical research communications 2021 Apr 30;551:100-106

LRRK2 Inhibition Ameliorates Dexamethasone-Induced Glucose Intolerance via Prevents Impairment in GLUT4 Membrane Translocation in Adipocytes.

Imai M, Kawakami F, Kubo M, Kanzaki M, Maruyama H, Kawashima R, Maekawa T, Kurosaki Y, Kojima F, Ichikawa T
Biological & pharmaceutical bulletin 2020;43(11):1660-1668

A novel rare variant of LRRK2 associated with familial Parkinson's disease: p.R1501W.

Masuzugawa S, Nishioka K, Imai Y, Ogata J, Shojima Y, Li Y, Yoshino H, Hattori N
Parkinsonism & related disorders 2020 Jul;76:46-48

Golgi-resident TRIO regulates membrane trafficking during neurite outgrowth.

Tao T, Sun J, Peng Y, Li Y, Wang P, Chen X, Zhao W, Zheng YY, Wei L, Wang W, Zhou Y, Liu J, Shi YS, Zhu MS
The Journal of biological chemistry 2019 Jul 12;294(28):10954-10968

Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway.

Lian Y, Xiong F, Yang L, Bo H, Gong Z, Wang Y, Wei F, Tang Y, Li X, Liao Q, Wang H, Zhou M, Xiang B, Wu X, Li Y, Li X, Chen X, Li G, Guo C, Zeng Z, Xiong W
Journal of experimental & clinical cancer research : CR 2018 Oct 16;37(1):253

MARCKS is Necessary for Oligodendrocyte Precursor Cell Maturation.

Zhang ZH, Ma FF, Zhang H, Xu XH
Neurochemical research 2017 Oct;42(10):2933-2939

Rab10 Disruption Results in Delayed OPC Maturation.

Zhang ZH, Zhao WQ, Ma FF, Zhang H, Xu XH
Cellular and molecular neurobiology 2017 Oct;37(7):1303-1310

Quantitative proteome analysis of colorectal cancer-related differential proteins.

Zhang Y, Liu Y, Ye Y, Shen D, Zhang H, Huang H, Li S, Wang S, Ren J
Journal of cancer research and clinical oncology 2017 Feb;143(2):233-241

AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis.

Zeng Z, Bo H, Gong Z, Lian Y, Li X, Li X, Zhang W, Deng H, Zhou M, Peng S, Li G, Xiong W
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):729-37

Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.

Bo H, Gong Z, Zhang W, Li X, Zeng Y, Liao Q, Chen P, Shi L, Lian Y, Jing Y, Tang K, Li Z, Zhou Y, Zhou M, Xiang B, Li X, Yang J, Xiong W, Li G, Zeng Z
Oncotarget 2015 Aug 21;6(24):20404-18

MARCKS regulates membrane targeting of Rab10 vesicles to promote axon development.

Xu XH, Deng CY, Liu Y, He M, Peng J, Wang T, Yuan L, Zheng ZS, Blackshear PJ, Luo ZG
Cell research 2014 May;24(5):576-94

JIP1 mediates anterograde transport of Rab10 cargos during neuronal polarization.

Deng CY, Lei WL, Xu XH, Ju XC, Liu Y, Luo ZG
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Jan 29;34(5):1710-23

Semaphorin 3A activates the guanosine triphosphatase Rab5 to promote growth cone collapse and organize callosal axon projections.

Wu KY, He M, Hou QQ, Sheng AL, Yuan L, Liu F, Liu WW, Li G, Jiang XY, Luo ZG
Science signaling 2014 Aug 26;7(340):ra81

Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon development.

Liu Y, Xu XH, Chen Q, Wang T, Deng CY, Song BL, Du JL, Luo ZG
Nature communications 2013;4:2005

Adaptor protein complex 2-mediated, clathrin-dependent endocytosis, and related gene activities, are a prominent feature during maturation stage amelogenesis.

Lacruz RS, Brookes SJ, Wen X, Jimenez JM, Vikman S, Hu P, White SN, Lyngstadaas SP, Okamoto CT, Smith CE, Paine ML
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Mar;28(3):672-87

Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis.

Pavlos NJ, Grønborg M, Riedel D, Chua JJ, Boyken J, Kloepper TH, Urlaub H, Rizzoli SO, Jahn R
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Oct 6;30(40):13441-53

Identification of transgelin-2 as a biomarker of colorectal cancer by laser capture microdissection and quantitative proteome analysis.

Zhang Y, Ye Y, Shen D, Jiang K, Zhang H, Sun W, Zhang J, Xu F, Cui Z, Wang S
Cancer science 2010 Feb;101(2):523-9

Wang D, Lou J, Ouyang C, Chen W, Liu Y, Liu X, Cao X, Wang J, Lu L
Proceedings of the National Academy of Sciences of the United States of America 2010 Aug 3;107(31):13806-11

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: human brain tissue were subjected to SDS PAGE followed by western blot with 11808-1-AP(RAB10 antibody) at dilution of 1:400
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The RAB10 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RAB10. This antibody recognizes human,mouse,rat antigen. The RAB10 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Appendix: 11808-1-AP.pdf

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