Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- BS5857 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- PIP5KIÎÛ polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 346-391 of Human PIP5KIÎÛ.
- Description
- Phosphatidylinositol-4-phosphate-5-kinase (PIPK) synthesizes phosphatidylinositol-4,5-bisphosphate, which regulates various processes including cell proliferation, survival, membrane trafficking and cytoskeletal organization. The PIPK family is divided into type I, type II and type III. Each type of the PIPK family phosphorylates distinct substrates. They contain an activation loop, which determines their enzymatic specificity and subcellular targeting. The phosphatidylinositol-4-phosphate-5-kinase type I consists of three members, PIPK I Ï«, ÉÇ and ÎÛ, which are characterized by phosphorylating PI4P on the 5-hydroxyl. PIPK I Ï«, designated PIPK I ÉÇ in mouse, is expressed in brain tissue. PIPK I ÉÇ, designated PIPK I Ï« in mouse, is also called STM7. PIPK I ÎÛ has two variants produced by alternative splicing which are expressed in lung, brain and kidneys.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
No comments: Submit comment
Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of PIP5KI¦Ã pAb at 1:500 dilutionLane1:Hela cell lysateLane2:Raw264.7 cell lysateLane3:PC12 cell lysate