PA5-63290

antibody from Invitrogen Antibodies

Targeting: CYP11B1 CPN1, CYP11B, FHI, P450C11

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

PA5-63290

Provider

Invitrogen Antibodies

Product name

CYP11B1 Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Recombinant full-length protein

Description

Immunogen sequence: RFLPMVDAVA RDFSQALKKK VLQNARGSLT LDVQPSIFHY TIEASNLALF GERLGLVGHS PSSASLNFLH ALEVMFKSTV QLMFMPR Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 72%.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100 µL

Concentration

0.10 mg/mL

Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

References

Submitted references

Mass spectrometry-based steroid profiling in primary bilateral macronodular adrenocortical hyperplasia.

Hannah-Shmouni F, Berthon A, Faucz FR, Briceno JM, Maria AG, Demidowich A, Peitzsch M, Masjkur J, Bonnet-Serrano F, Vaczlavik A, Bertherat J, Reincke M, Eisenhofer G, Stratakis CA
Endocrine-related cancer 2020 Jul;27(7):403-413

---

High expression of adrenal P450 aromatase (CYP19A1) in association with ARMC5-primary bilateral macronodular adrenocortical hyperplasia.

Berthon A, Hannah-Shmouni F, Maria AG, Faucz FR, Stratakis CA
The Journal of steroid biochemistry and molecular biology 2019 Jul;191:105316

---

The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion.

Scortegagna M, Berthon A, Settas N, Giannakou A, Garcia G, Li JL, James B, Liddington RC, Vilches-Moure JG, Stratakis CA, Ronai ZA
JCI insight 2017 Dec 7;2(23)